Optimization of Digital Overcurrent Protection Settings in DC Urban Light Railway Systems

DC urban light railway systems are used for public transportation in many towns worldwide. In these systems, short circuit currents are often similar, both in steady state magnitude and in rate-of-rise, to normal operation currents. In order to properly set the protection relays, to obtain short circuit discrimination and to avoid nuisance trippings, it is important to analyze short circuit and normal operation current patterns. It is also important to highlight that normal operation current patterns are not only those related to rolling stock acceleration, but also to zone commutation. This paper presents the results of several measurement campaigns, performed for this purpose, on the tram network of Turin, Italy. The measurements results are then used to propose optimized settings for the installed overcurrent protections

Impact of MV Ground Fault Current Distribution on Global Earthing Systems

Global earthing systems (GESs), created by the interconnection of local earthing systems, should guarantee the absence of dangerous touch voltages. One of the reasons for this safety characteristic of GESs is the fault current distribution between grounding electrodes and medium-voltage (MV) cable sheaths: Only a small portion of the fault current is injected into the ground by the ground grid of the faulty substation. In systems with isolated neutral or with resonant earthing, this effect may be sufficient to provide safety from electric shock. In this paper, a model describing the behavior of the MV distribution system with interconnected grounding electrodes during a ground fault is built. It is then used to analyze the impact of different factors on the fault current distribution. A sensitivity analysis is performed, varying the main parameters, and the results are used to draw some conclusions on the current distribution influence on GESs

Reflexões críticas sobre a declaração de inconstitucionalidade de ofício

Este artigo pretende expor os diferentes argumentos e posições quanto à possibilidade da declaração de inconstitucionalidade ex officio. Procuraremos demonstrar que a questão esconde complexidades que não podem ser ignoradas quando do tratamento do tema. Propomos, nesse sentido, que é possível cogitar a criação de um modelo que considere as diversas implicações de se proibir ou obrigar o controle de constitucionalidade de ofício. O trabalho utiliza a metodologia analítica, pois, através de estudos da doutrina e da jurisprudência, nacional e estrangeira, desenvolve os argumentos que hoje se colocam, estabelecendo (i) um panorama para a criação de um modelo capaz de absorver as diversas implicações da questão e (ii) uma base para uma crítica construtiva dos modelos que hoje se impõem. Ao final, concluímos que, de fato, o tema merece ser repensado no âmbito da doutrina e da jurisprudência brasileiras, pois se trata de problemática de alta relevância e complexidade, cujas implicações se observam na separação e equilíbrio entre os poderes

Global Earthing System: Can Buried Metallic Structures Significantly Modify the Ground Potential Profile?

Global earthing systems (GESs), which are created by the interconnection of local earthing systems, should guarantee the absence of dangerous touch voltages. According to international standards, one of the reasons for this safety characteristic of GESs is that medium-voltage and low-voltage grounding systems form a quasi-equipotential area. Typical examples of GESs are in city centers due to the high number of interconnected grounding systems in the area. For this reason, in addition to ground grids, other metallic parts with different primary functions shall be also considered, e.g., water and gas pipes, tramway tracks, and building foundations can modify the electric potential distribution in the area. In this paper, a model based on the Maxwell's subareas method (MaSM) is used to evaluate how buried metallic parts, which are not intentionally connected to ground grids, modify the electric potential on the soil surface. First, the MaSM model is validated with experimental measurements on a simple electrode configuration. The measured voltages are compared with the MaSM results and with the results obtained with a finite-element method model simulated with COMSOL Multiphysics. Then, the simulations are carried out on a realistic urban test case

Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems

The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum. We investigated whether the growth factor combination transforming growth factor beta 1/fibroblast growth factor 2/platelet-derived growth factor BB (TFP), recently shown to enhance the proliferation capacity of human articular chondrocytes (HACs), allows the efficiency of chondrocyte use to be increased at different seeding densities and percentages of human serum (HS). HACs were seeded at 1,000, 5,000, and 10,000 celIS/cm(2) in medium containing 10 bovine serum or 10,000 cells/cm(2) with 1 chondrogenic capacity of post-expanded HACs was then assessed in pellet cultures. Expansion with TFP allowed a sufficient number of HACs to be obtained in one passage even at the lowest seeding density and HS percentage and variability in cartilage-forming capacity of HACs expanded under the different conditions to be reduced. Instead, larger variations and insufficient yields were found in the absence of TFP. By allowing large numbers of cells to be obtained, starting from a wide range of initial seeding densities and HS percentages, the use of TFP may represent a viable solution for the efficient expansion of HACs and addresses constraints of automated clinical bioreactor systems

Exploring the Distinct Effect of Age at Onset and Caudate Denervation on Cognitive Deficits in Early Parkinson's Disease

Older age at onset and baseline caudate dopaminergic denervation are recognized risk factors for cognitive impairment in Parkinson's disease (PD), posing challenges in identifying their relative contribution to cognitive outcomes. The objective of this study was to assess the distinct contribution of age at onset and baseline caudate dopaminergic binding to the early cognitive deficits in PD patients. We examined the relationship between baseline dopaminergic striatal dysfunction (measured using [ 123 I]-FP-CIT SPECT), age at disease onset and neuropsychological performance in 128 drug-naive PD patients, utilizing putaminal and caudate binding values of 77 healthy controls (HC) for a comparative exploration of age-dependent loss of DAT availability. Additionally, we investigated whether age at onset and DAT binding value of the caudate could independently predict cognitive changes over a median of 7-year follow-up. [ 123 I]-FP-CIT-SPECT binding values had a significant negative correlation with age in both PD and HC, but in PD, aging was linked with a steeper slope for the caudate than the putamen. Older age at onset and lower caudate uptake were associated with worse global cognitive function and performance in specific neuropsychological tests at baseline and demonstrated to be significant independent predictors of cognitive dysfunction at follow-up. Our findings confirm a differential age effect on [ 123 I]-FP-CIT binding in the striatal subregions of de novo PD patients. Notably, we found less age-related attrition of dopaminergic binding in the putamen than in the caudate, reflecting likely the superimposition of putaminal compensatory mechanisms and an increased predisposition of old onset PD patients to develop cognitive disturbances

Prevalence of Klebsiella pneumoniae strains producing carbapenemases and increase of resistance to colistin in an Italian teaching hospital from January 2012 To December 2014

The aim of this study was to characterize the spread of carbapenemase-producing Klebsiella pneumoniae (CPKP) in a tertiary level hospital using ongoing active surveillance with rectal swab cultures. Furthermore, this study analyzed the presence of CPKP in the clinical samples (CS) of a single patient as well as the evolution of Colistin-sensitive strains (CoS) to Colistin-resistant strains (CoR)

Influence of LV Neutral Grounding on Global Earthing Systems

International Standards define a Global Earthing System as an earthing net created interconnecting local Earthing Systems (generally through the shield of MV cables and/or bare buried conductors). In Italy, the regulatory authority for electricity and gas requires distributors to guarantee the electrical continuity of LV neutral conductor. This requirement has led to the standard practice of realizing “reinforcement groundings” along the LV neutral conductor path and at users' delivery cabinet. Moreover, in urban high-load scenarios (prime candidates to be part of a Global Earthing System), it is common that LV distribution scheme creates, through neutral conductors, an effective connection between grounding systems of MV/LV substations, modifying Global Earthing System consistency. The aim of this paper is to evaluate the effect, in terms of electrical safety, of the aforementioned LV neutral distribution scheme when an MV-side fault to ground occurs. For this purpose, simulations are carried out on a realistic urban test case and suitable evaluation indexes are proposed