4,944 research outputs found
Black Rings, Boosted Strings and Gregory-Laflamme
We investigate the Gregory-Laflamme instability for black strings carrying
KK-momentum along the internal direction. We demonstrate a simple kinematical
relation between the thresholds of the classical instability for the boosted
and static black strings. We also find that Sorkin's critical dimension depends
on the internal velocity and in fact disappears for sufficiently large boosts.
Our analysis implies the existence of an analogous instability for the
five-dimensional black ring of Emparan and Reall. We also use our results for
boosted black strings to construct a simple model of the black ring and argue
that such rings exist in any number of space-time dimensions.Comment: 26 pages, 6 figure
New rock magnetic and paleomagnetic results for the 1.64 Ga Suomenniemi dyke swarm, SE Finland
Peer reviewe
Algebraic Solutions of the Lam\'e Equation, Revisited
A minor error in the necessary conditions for the algebraic form of the
Lam\'e equation to have a finite projective monodromy group, and hence for it
to have only algebraic solutions, is pointed out. [See F. Baldassarri, "On
algebraic solutions of Lam\'e's differential equation", J. Differential
Equations 41 (1981), 44-58.] It is shown that if the group is the octahedral
group S_4, then the degree parameter of the equation may differ by +1/6 or -1/6
from an integer; this possibility was missed. The omission affects a recent
result on the monodromy of the Weierstrass form of the Lam\'e equation. [See R.
C. Churchill, "Two-generator subgroups of SL(2,C) and the hypergeometric,
Riemann, and Lam\'e equations", J. Symbolic Computation 28 (1999), 521-545.]
The Weierstrass form, which is a differential equation on an elliptic curve,
may have, after all, an octahedral projective monodromy group.Comment: 20 pages, elsart document class, no figure
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Neuropsychological Functioning in Active Duty Soldiers with Physical and/or Psychological Trauma
This quasi-experimental study investigates neuropsychological functioning differences between 63 active duty soldiers who were placed into three groups (MTBI, PTSD, control) to provide better information for differentiating PTSD and MTBI. The ANAM and MicroCog were utilized to measure psychomotor speed, memory, and attention. Participants with PTSD performed worse on most measures of psychomotor speed and attention, and endorsed more symptoms of depression and anxiety when compared to MTBI and control participants. Further, attention appears to be the best cognitive domain for differentiating PTSD from MTBI, whereas memory variables did not differentiate these groups. Clinical and research implications of these findings are discussed
Sub-Alfvenic Non-Ideal MHD Turbulence Simulations with Ambipolar Diffusion: I. Turbulence Statistics
Most numerical investigations on the role of magnetic fields in turbulent
molecular clouds (MCs) are based on ideal magneto-hydrodynamics (MHD). However,
MCs are weakly ionized, so that the time scale required for the magnetic field
to diffuse through the neutral component of the plasma by ambipolar diffusion
(AD) can be comparable to the dynamical time scale. We have performed a series
of 256^3 and 512^3 simulations on supersonic but sub-Alfvenic turbulent systems
with AD using the Heavy-Ion Approximation developed in Li, McKee, & Klein
(2006). Our calculations are based on the assumption that the number of ions is
conserved, but we show that these results approximately apply to the case of
time-dependent ionization in molecular clouds as well. Convergence studies
allow us to determine the optimal value of the ionization mass fraction when
using the heavy-ion approximation for low Mach number, sub-Alfvenic turbulent
systems. We find that ambipolar diffusion steepens the velocity and magnetic
power spectra compared to the ideal MHD case. Changes in the density PDF, total
magnetic energy, and ionization fraction are determined as a function of the AD
Reynolds number. The power spectra for the neutral gas properties of a strongly
magnetized medium with a low AD Reynolds number are similar to those for a
weakly magnetized medium; in particular, the power spectrum of the neutral
velocity is close to that for Burgers turbulence.Comment: 37 pages, 11 figures, 4 table
Sex and Gender in Medical Education, and proceedings from the 2015 Sex and Gender Education Summit
The Sex and Gender Medical Education Summit: a roadmap for curricular innovation was a collaborative initiative of the American Medical Women\u27s Association, Laura W. Bush Institute for Women’s Health, Mayo Clinic, and Society for Women\u27s Health Research (www.sgbmeducationsummit.com). It was held on October 18–19, 2015 to provide a unique venue for collaboration among nationally and internationally renowned experts in developing a roadmap for the incorporation of sex and gender based concepts into medical education curricula. The Summit engaged 148 in-person attendees for the 1 1/2-day program. Pre- and post-Summit surveys assessed the impact of the Summit, and workshop discussions provided a framework for informal consensus building. Sixty-one percent of attendees indicated that the Summit had increased their awareness of the importance of sex and gender specific medicine. Other comments indicate that the Summit had a significant impact for motivating a call to action among attendees and provided resources to initiate change in curricula within their home institutions. These educational efforts will help to ensure a sex and gender basis for delivery of health care in the future
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival.
Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking. The nuclear receptor LRH-1 (NR5A2) is expressed in intestinal epithelium and thought to contribute to epithelial renewal. Here we show that LRH-1 maintains intestinal epithelial health and protects against inflammatory damage. Knocking out LRH-1 in murine intestinal organoids reduces Notch signaling, increases crypt cell death, distorts the cellular composition of the epithelium, and weakens the epithelial barrier. Human LRH-1 (hLRH-1) rescues epithelial integrity and when overexpressed, mitigates inflammatory damage in murine and human intestinal organoids, including those derived from IBD patients. Finally, hLRH-1 greatly reduces disease severity in T-cell-mediated murine colitis. Together with the failure of a ligand-incompetent hLRH-1 mutant to protect against TNFα-damage, these findings provide compelling evidence that hLRH-1 mediates epithelial homeostasis and is an attractive target for intestinal disease
Classical Stabilization of Homogeneous Extra Dimensions
If spacetime possesses extra dimensions of size and curvature radii much
larger than the Planck or string scales, the dynamics of these extra dimensions
should be governed by classical general relativity. We argue that in general
relativity, it is highly nontrivial to obtain solutions where the extra
dimensions are static and are dynamically stable to small perturbations. We
also illustrate that intuition on equilibrium and stability built up from
non-gravitational physics can be highly misleading. For all static, homogeneous
solutions satisfying the null energy condition, we show that the Ricci
curvature of space must be nonnegative in all directions. Much of our analysis
focuses on a class of spacetime models where space consists of a product of
homogeneous and isotropic geometries. A dimensional reduction of these models
is performed, and their stability to perturbations that preserve the spatial
symmetries is analyzed. We conclude that the only physically realistic examples
of classically stabilized large extra dimensions are those in which the
extra-dimensional manifold is positively curved.Comment: 25 pages; minor changes, improved reference
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