577 research outputs found

    Simulation of Unsteady Flows Using an Unstructured Navier-Stokes Solver on Moving and Stationary Grids

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    We apply an unsteady Reynolds-averaged Navier-Stokes (URANS) solver for unstructured grids to unsteady flows on moving and stationary grids. Example problems considered are relevant to active flow control and stability and control. Computational results are presented using the Spalart-Allmaras turbulence model and are compared to experimental data. The effect of grid and time-step refinement are examined

    Factors Associated With Unplanned Hospitalizations Among Patients With Nonmetastatic Colorectal Cancers Intended for Treatment in the Ambulatory Setting

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    Chemotherapy administration and supportive management for solid tumors is intended to take place in the ambulatory setting, but little is known about why some patients experience treatment-related, adverse events so severe as to require acute inpatient care

    Next Generation Community Leaders Initiative: Collaborating With Youth to Develop Leaders and Healthier Communities

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    Central to addressing the social determinants of health and challenges to health equity in the United States is the growing acknowledgement among solution seekers of the importance of cross-sector collaborators and partners. Youth are an underutilized and overlooked partner, especially in vulnerable urban communities, who bring diverse perspectives on their communities. Provided the opportunity and resources (e.g., coaching, compensation, and connections), youth can add value as partners to solve problems and achieve goals to benefit their communities. In this paper we review and discuss the Next Generation Community Leaders initiative (NGCL) a $2.8 million initiative funded by New Jersey Health Initiatives, the statewide grantmaking program of the Robert Wood Johnson Foundation. We also describe findings from an independent evaluation of NGCL that explored how investments in youth through youth-serving organizations benefitted the youth who participated and increased health equity in their communities. Finally, we share 5 principles of youth engagement that we identified through our work as practitioners and scholars

    Long-Term Use of Nonsteroidal Anti-inflammatory Drugs Decreases the Risk of Cutaneous Melanoma: Results of a United States Case–Control Study

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    Experimental and observational studies continue to demonstrate conflicting results regarding the role of several commonly used drugs as melanoma chemopreventive agents. This case–control study was designed to assess the associations between cutaneous melanoma (CM) and exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) and statins in current users. A total of 400 CM and 600 eligible age- and gender-matched community-based controls were prospectively recruited and interviewed. We assessed participants’ demographic characteristics, CM risk factors, and current and previous use of medications. Multivariable conditional logistic regression models were used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for associations between NSAIDs and/or aspirin (ASA), statin exposure, and CM risk. Half of the subjects were men (mean age 60 years). After adjusting for confounders, use of any type of NSAIDs for more than 5 years significantly reduced the risk of melanoma development compared with the low-exposure group (adjusted OR=0.57; 95% CI=0.43–0.77). Subgroup analyses showed that the observed risk reduction was primarily driven by continuous ASA use (>5 years adjusted OR=0.51, 95% CI=0.35–0.75). No significant protective effect was observed with statin exposure (OR=0.97, 95% CI=0.73–1.29). Long-term use of NSAIDs, especially ASA, is associated with a significantly decreased risk of CM development. Clinical intervention studies are warranted to further investigate the potential role of ASA and other NSAIDs as chemopreventive agents for CM.JID JOURNAL CLUB ARTICLE: For questions, answers, and open discussion about this article, please go to http://www.nature.com/jid/journalclu

    Estimating Effect of Antiviral Drug Use during Pandemic (H1N1) 2009 Outbreak, United States

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    From April 2009 through March 2010, during the pandemic (H1N1) 2009 outbreak, ≈8.2 million prescriptions for influenza neuraminidase-inhibiting antiviral drugs were filled in the United States. We estimated the number of hospitalizations likely averted due to use of these antiviral medications. After adjusting for prescriptions that were used for prophylaxis and personal stockpiles, as well as for patients who did not complete their drug regimen, we estimated the filled prescriptions prevented ≈8,400–12,600 hospitalizations (on the basis of median values). Approximately 60% of these prevented hospitalizations were among adults 18–64 years of age, with the remainder almost equally divided between children 0–17 years of age and adults >65 years of age. Public health officials should consider these estimates an indication of success of treating patients during the 2009 pandemic and a warning of the need for renewed planning to cope with the next pandemic

    Lower Bounds and Series for the Ground State Entropy of the Potts Antiferromagnet on Archimedean Lattices and their Duals

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    We prove a general rigorous lower bound for W(Λ,q)=exp(S0(Λ,q)/kB)W(\Lambda,q)=\exp(S_0(\Lambda,q)/k_B), the exponent of the ground state entropy of the qq-state Potts antiferromagnet, on an arbitrary Archimedean lattice Λ\Lambda. We calculate large-qq series expansions for the exact Wr(Λ,q)=q1W(Λ,q)W_r(\Lambda,q)=q^{-1}W(\Lambda,q) and compare these with our lower bounds on this function on the various Archimedean lattices. It is shown that the lower bounds coincide with a number of terms in the large-qq expansions and hence serve not just as bounds but also as very good approximations to the respective exact functions Wr(Λ,q)W_r(\Lambda,q) for large qq on the various lattices Λ\Lambda. Plots of Wr(Λ,q)W_r(\Lambda,q) are given, and the general dependence on lattice coordination number is noted. Lower bounds and series are also presented for the duals of Archimedean lattices. As part of the study, the chromatic number is determined for all Archimedean lattices and their duals. Finally, we report calculations of chromatic zeros for several lattices; these provide further support for our earlier conjecture that a sufficient condition for Wr(Λ,q)W_r(\Lambda,q) to be analytic at 1/q=01/q=0 is that Λ\Lambda is a regular lattice.Comment: 39 pages, Revtex, 9 encapsulated postscript figures, to appear in Phys. Rev.

    The Grizzly, February 25, 1983

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    USGA Plans Communication Revision • Foley, D\u27Alesio First Place Winners at Talent Show • College Union Holds Tenth Anniversary • Ritter Production Opens: Skin of Our Teeth • Mass is Popular: Newman Society Links U.C. • Small Heads Alcohol Committee • SPC Seeks Editors • Union Calendar • Grizzly Looks For New Business Manager • Winterfest 1983: International Desserts Festival Tonight • Winterfest Schedule • Letters to the Editor: Admissions Dean Corrects Errors; Hoop Club President Responds; Student Reacts Negatively • Social Life at Ursinus Should be Improved • In the Gates • Registrar Announces Pre-Registration • President\u27s Corner • Roving Reporter: Do You Think the New Alcohol Policy Proposed by the Administration was the Correct Way to Handle the Situations That Occurred on Campus? • Bears Drown Monarchs • Women\u27s Swimming Ends 10-1 • MAC Competition: Wrestlers Take Seventh • Gymnasts Move up a Rank • Lady Hoopsters Finish With Victoryhttps://digitalcommons.ursinus.edu/grizzlynews/1095/thumbnail.jp

    The Erotic and the Vulgar: Visual Culture and Organized Labor's Critique of U.S. Hegemony in Occupied Japan

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    This essay engages the colonial legacy of postwar Japan by arguing that the political cartoons produced as part of the postwar Japanese labor movement’s critique of U.S. cultural hegemony illustrate how gendered discourses underpinned, and sometimes undermined, the ideologies formally represented by visual artists and the organizations that funded them. A significant component of organized labor’s propaganda rested on a corpus of visual media that depicted women as icons of Japanese national culture. Japan’s most militant labor unions were propagating anti-imperialist discourses that invoked an engendered/endangered nation that accentuated the importance of union roles for men by subordinating, then eliminating, union roles for women
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