Altitude Cooling Investigation of the R-2800-21 Engine in the P-47G Airplane. IV - Engine Cooling-Air Pressure Distribution

A study of the data obtained in a flight investigation of an R-2800-21 engine in a P-47G airplane was made to determine the effect of the flight variables on the engine cooling-air pressure distribution. The investigation consisted of level flights at altitudes from 5000 to 35,000 feet for the normal range of engine and airplane operation. The data showed that the average engine front pressures ranged from 0.73 to 0.82 of the impact pressure (velocity head). The average engine rear pressures ranged from 0.50 to 0.55 of the impact pressure for closed cowl flaps and from 0.10 to 0.20 for full-open cowl flaps. In general, the highest front pressures were obtained at the bottom of the engine. The rear pressures for the rear-row cylinders were .lower and the pressure drops correspondingly higher than for the front-row cylinders. The rear-pressure distribution was materially affected by cowl-flap position in that the differences between the rear pressures of the front-row and rear-row cylinders markedly increased as the cowl flaps were opened. For full-open cowl flaps, the pressure drops across the rear-row cylinders were in the order of 0.2 of the impact pressure greater than across the front-row cylinders. Propeller speed and altitude had little effect on the -coolingair pressure distribution, Increase in angle of inclination of the thrust axis decreased the front ?pressures for the cylinders at the top of the engine and increased them for the cylinders at the bottom of the engine. As more auxiliary air was taken from the engine cowling, the front pressures and, to a lesser extent, the rear pressures for the cylinders at the bottom of the engine decreased. No correlation existed between the cooling-air pressure-drop distribution and the cylinder-temperature distribution

A New Algorithm for Retrieving Aerosol Properties Over Land from MODIS Spectral Reflectance

Since first light in early 2000, operational global quantitative retrievals of aerosol properties over land have been made from MODIS observed spectral reflectance. These products have been continuously evaluated and validated, and opportunities for improvements have been noted. We have replaced the original algorithm by improving surface reflectance assumptions, the aerosol model optical properties and the radiative transfer code used to create the lookup tables. The new algorithm (known as Version 5.2 or V5.2) performs a simultaneous inversion of two visible (0.47 and 0.66 micron) and one shortwave-IR (2.12 micron) channel, making use of the coarse aerosol information content contained in the 2.12 micron channel. Inversion of the three channels yields three nearly independent parameters, the aerosol optical depth (tau) at 0.55 micron, the non-dust or fine weighting (eta) and the surface reflectance at 2.12 micron. Finally, retrievals of small magnitude negative tau values (down to -0.05) are considered valid, thus normalizing the statistics of tau in near zero tau conditions. On a 'test bed' of 6300 granules from Terra and Aqua, the products from V5.2 show marked improvement over those from the previous versions, including much improved retrievals of tau, where the MODIS/AERONET tau (at 0.55 micron) regression has an equation of: y = 1.01+0.03, R = 0.90. Mean tau for the test bed is reduced from 0.28 to 0.21

Health-Related Quality of Life in Adults From 17 Family Practice Clinics in North Carolina

Introduction: We examined health-related quality of life (HRQOL) in white and African American patients based on their own and their community's socioeconomic status. Methods: Participants were 4,565 adults recruited from 17 family physician practices in urban and rural areas of North Carolina. Education was used as a proxy for individual socioeconomic status, and the census block-group poverty level was used as a proxy for community socioeconomic status. HRQOL measures were the 12-Item Short Form Survey Instrument, physical component summary (PCS) and mental component summary (MCS), and 3 Centers for Disease Control and Prevention HRQOL healthy days measures. Multilevel analyses examined independent associations of individual and community poverty level with HRQOL, adjusting for demographics and clustering by family practice. Analyses were stratified by race and were conducted on subgroups of arthritis and cardiovascular disease patients. Results: Among whites, all 5 HRQOL measures were significantly associated with the lowest individual socioeconomic status, and 4 HRQOL measures were associated with the lowest community socioeconomic status (MCS being the exception). Among African Americans, 4 HRQOL measures were significantly associated with the lowest individual socioeconomic status and the lowest community socioeconomic status (PCS being the exception). Arthritis and cardiovascular disease subgroup analyses showed generally analogous findings. Conclusion: Better HRQOL measures generally were associated with low levels of community poverty and high levels of education, emphasizing the need for further exploration of factors that influence health

Spitzer IRS Observations of the Galactic Center: Shocked Gas in the Radio Arc Bubble

We present Spitzer IRS spectra (R ~600, 10 - 38 micron) of 38 positions in the Galactic Center (GC), all at the same Galactic longitude and spanning plus/minus 0.3 degrees in latitude. Our positions include the Arches Cluster, the Arched Filaments, regions near the Quintuplet Cluster, the ``Bubble'' lying along the same line-of-sight as the molecular cloud G0.11-0.11, and the diffuse interstellar gas along the line-of-sight at higher Galactic latitudes. From measurements of the [O IV], [Ne II], [Ne III], [Si II], [S III], [S IV], [Fe II], [Fe III], and H_2 S(0), S(1), and S(2) lines we determine the gas excitation and ionic abundance ratios. The Ne/H and S/H abundance ratios are ~ 1.6 times that of the Orion Nebula. The main source of excitation is photoionization, with the Arches Cluster ionizing the Arched Filaments and the Quintuplet Cluster ionizing the gas nearby and at lower Galactic latitudes including the far side of the Bubble. In addition, strong shocks ionize gas to O^{+3} and destroy dust grains, releasing iron into the gas phase (Fe/H ~ 1.3 times 10^{-6} in the Arched Filaments and Fe/H ~ 8.8 times 10^{-6} in the Bubble). The shock effects are particularly noticeable in the center of the Bubble, but O$^{+3}$ is present in all positions. We suggest that the shocks are due to the winds from the Quintuplet Cluster Wolf-Rayet stars. On the other hand, the H_2 line ratios can be explained with multi-component models of warm molecular gas in photodissociation regions without the need for H_2 production in shocks.Comment: 51 pages, 17 figures To be published in the Astrophysical Journa

Forum: Parental education and child mortality

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Calibration and performance of the Galileo solid-state imaging system in Jupiter orbit

The solid-state imaging subsystem (SSI) on the National Aeronautics and Space Administration’s (NASA’s) Galileo Jupiter orbiter spacecraft has successfully completed its 2-yr primary mission exploring the Jovian system. The SSI has remained in remarkably stable calibration during the 8-yr flight, and the quality of the returned images is exceptional. Absolute spectral radiometric calibration has been determined to 4 to 6% across its eight spectral filters. Software and calibration files are available to enable radiometric, geometric, modulation transfer function (MTF), and scattered light image calibration. The charge-coupled device (CCD) detector endured the harsh radiation environment at Jupiter without significant damage and exhibited transient image noise effects at about the expected levels. A lossy integer cosine transform (ICT) data compressor proved essential to achieving the SSI science objectives given the low data transmission rate available from Jupiter due to a communication antenna failure. The ICT compressor does introduce certain artifacts in the images that must be controlled to acceptable levels by judicious choice of compression control parameter settings. The SSI team’s expertise in using the compressor improved throughout the orbital operations phase and, coupled with a strategy using multiple playback passes of the spacecraft tape recorder, resulted in the successful return of 1645 unique images of Jupiter and its satellites

ISO--LWS observations of the two nearby spiral galaxies: NGC6946 and NGC1313

(Abridged) We present the analysis of the main FIR fine structure lines emission in NGC1313 and NGC6946. We calculate that a component probably associated with the diffuse disks contributes <~40% in N6946 and ~30 % in N1313 to the total [CII] emission. The main PDR physical parameters responsible for the neutral atomic gas emission in N1313 and N6946 do not significantly differ from what Malhotra etal (2001) found by modelling the integrated emission of a sample of 60 normal galaxies,although there are evidences for a beam averaged contribution of a less active component inside NGC6946 higher than its contribution in the integrated emission of normal galaxies. CO and [CII] in N6946 are well correlated with a mean [CII]/CO ratio similar to that of the normal galaxies sample. In N1313 the [CII]/CO seems to systematically increase from the North to the south, along the S-shaped spiral arm, indicating much more inhomogeneous conditions than in N6946. HI and [CII] in N6946 are completely de-correlated, probably because they arise from different gas components. In N1313 we successfully detect two distinct gas components: a cirrus-like component where HI and [CII] are weakly correlated as observed in our Galaxy, and a component associated with dense PDRs completely de-correlated from HI as observed in N6946.Finally, we find that the HI residing in dense PDRs and presumably recently photo-dissociated, constitutes a few % of the total HI. In turn, this dense gas component produces most of the [CII] emission emitted by the atomic neutral medium.Comment: Latex, 100 pages, 11 Figures, 11 Tables. Accepted for publication in A

Safety Findings in Pediatric Patients During Long-Term Treatment With Teduglutide for Short-Bowel Syndrome-Associated Intestinal Failure : Pooled Analysis of 4 Clinical Studies

Background This analysis assessed combined safety data from 4 clinical studies of teduglutide in pediatric patients with short-bowel syndrome-associated intestinal failure (SBS-IF). Methods Safety data from teduglutide-treated patients in 4 clinical trials were pooled. The completed 12-week and 24-week phase 3 core studies (NCT01952080/EudraCT 2013-004588-30 and NCT02682381/EudraCT 2015-002252-27) enrolled children aged 1-17 years with SBS-IF. Patients could elect to enroll in ongoing open-label extensions (NCT02949362/EudraCT 2016-000863-17 and NCT02954458/EudraCT 2016-000849-30). Interim data from ongoing studies were included. Results Safety data are reported for 89 pediatric patients treated with teduglutide for a median (range) of 51.7 (5.0-94.7) weeks. Adverse events (AEs) were reported in all patients; the most common were vomiting (51.7%), pyrexia (43.8%), upper respiratory tract infection (41.6%), and cough (33.7%). Thirty-five patients (39.3%) had AEs considered related to teduglutide treatment; abdominal pain and vomiting were most frequent (5.6% each). Three serious AEs in 3 patients (3.4%) were considered related to teduglutide treatment: ileus, d-lactic acidosis, and gastrointestinal obstruction due to hard stools. All 3 events resolved. One cecal polyp was detected, which was not biopsied or found on repeat colonoscopy. No cases of neoplasia occurred. Conclusion Based on integrated data from 4 clinical studies, including long-term follow-up forPeer reviewe

Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome : A 24-Week, Phase III Study

Background This study evaluated the safety and efficacy of teduglutide in pediatric patients with short bowel syndrome-associated intestinal failure (SBS-IF). Methods A 24-week, phase III trial with 2 randomized, double-blind teduglutide dose groups and a nonblinded standard of care (SOC) arm was used; patients received 0.025 mg/kg or 0.05 mg/kg teduglutide once daily. Safety end points included treatment-emergent adverse events (TEAEs) and growth parameters. The primary efficacy/pharmacodynamic end point was the number of patients who achieved a >= 20% reduction in parenteral support (PS) from baseline at week 24. Results All 59 enrolled patients completed the study (0.025 mg/kg, n = 24; 0.05 mg/kg, n = 26; SOC, n = 9). Baseline demographics and disease characteristics were comparable among groups. TEAEs were reported by 98% and 100% of patients in the teduglutide and SOC groups, respectively. The most common TEAEs in the teduglutide-treated groups were pyrexia and vomiting. The primary end point was achieved by 13 (54.2%), 18 (69.2%), and 1 (11.1%) patients who received 0.025 mg/kg teduglutide, 0.05 mg/kg teduglutide, and SOC, respectively (P <0.05 vs SOC). Both 0.025-mg/kg and 0.05-mg/kg teduglutide groups showed clinically significant reductions in PS volume (P <0.05 vs SOC), PS calories, days per week and hours per day of PS infusions, and increases in enteral nutrition and plasma citrulline at week 24 compared with baseline. Two (8.3%, 0.025 mg/kg teduglutide) and 3 patients (11.5%, 0.05 mg/kg teduglutide) achieved enteral autonomy. Conclusion The safety profile of teduglutide was similar to that reported previously in children and adults. Treatment with teduglutide was associated with significant reductions in PS for pediatric patients with SBS-IF over 24 weeks.Peer reviewe

Quantum dynamics in ultra-cold atomic physics

We review recent developments in the theory of quantum dynamics in ultra-cold atomic physics, including exact techniques, but focusing on methods based on phase-space mappings that are appli- cable when the complexity becomes exponentially large. These phase-space representations include the truncated Wigner, positive-P and general Gaussian operator representations which can treat both bosons and fermions. These phase-space methods include both traditional approaches using a phase-space of classical dimension, and more recent methods that use a non-classical phase-space of increased dimensionality. Examples used include quantum EPR entanglement of a four-mode BEC, time-reversal tests of dephasing in single-mode traps, BEC quantum collisions with up to 106 modes and 105 interacting particles, quantum interferometry in a multi-mode trap with nonlinear absorp- tion, and the theory of quantum entropy in phase-space. We also treat the approach of variational optimization of the sampling error, giving an elementary example of a nonlinear oscillator