267 research outputs found
Nickel Mixing in the Outer Layers of SN 1987A
Supernova 1987A remains the most well-observed and well-studied supernova to
date. Observations produced excellent broad-band photometric and spectroscopic
coverage over a wide wavelength range at all epochs. Here, we focus on the very
early spectroscopic observations. Only recently have numerical models been of
sufficient detail to accurately explain the observed spectra. In SN 1987A, good
agreement has been found between observed and synthetic spectra for day one,
but by day four, the predicted Balmer lines become much weaker than the
observed lines. We present the results of work based on a
radiation-hydrodynamic model by Blinnikov and collaborators. Synthetic non-LTE
spectra generated from this model by the general radiation transfer code
PHOENIX strongly support the theory that significant mixing of nickel into the
outer envelope is required to maintain strong Balmer lines. Preliminary results
suggest a lower limit to the average nickel mass of 1.0 \times 10^{-5} solar
masses is required above 5000 \kmps by day four. PHOENIX models thus have the
potential to be a sensitive probe for nickel mixing in the outer layers of a
supernova.Comment: 16 pages, 7 figures, ApJ, v556 2001 (in press
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Final LDRD Report for the Project Entitled: Biosensors Based on the Electrical Impedance of Tethered Lipid Bilayers on Planar Electrodes
Impedance based, planar chemical microsensors are the easiest sensors to integrate with electronics. The goal of this work is a several order of magnitude increase in the sensitivity of this sensor type. The basic idea is to mimic biological chemical sensors that rely on changes in ion transport across very thin organic membranes (supported Bilayer Membranes: sBLMs) for the sensing. To improve the durability of bilayers we show how they can be supported on planar metal electrodes. The large increase in sensitivity over polyelectrolytes will come from molecular recognition elements like antibodies that bind the analyte molecule. The molecular recognition sites can be tied to the lipid bilayer capacitor membrane and a number of mechanisms can be used to modulate the impedance of the lipid bilayers. These include coupled ion channels, pore modification and double layer capacitance modification by the analyte molecule. The planar geometry of our electrodes allows us to create arrays of sensors on the same chip, which we are calling the ''Lipid Chip''
Optical Spectra of the Type Ia Supernova 1998aq
We present 29 optical spectra of the normal Type Ia SN 1998aq, ranging from 9
days before to 241 days after the time of maximum brightness. This
spectroscopic data set, together with photometric data presented elsewhere,
makes SN 1998aq one of the best observed Type Ia supernova at optical
wavelengths. We use the parameterized supernova synthetic-spectrum code SYNOW
to study line identifications in the early photospheric-phase spectra. The
results include evidence for lines of singly ionized carbon, at ejection
velocities as low as 11,000 km/sec. Implications for explosion models are
discussed.Comment: 40 pages including 20 figures and 4 tables. Accepted by A
Using Line Profiles to Test the Fraternity of Type Ia Supernovae at High and Low Redshifts
Using archival data of low-redshift (z < 0.01) Type Ia supernovae (SN Ia) and
recent observations of high-redshift (0.16 < z <0.64; Matheson et al. 2005) SN
Ia, we study the "uniformity'' of the spectroscopic properties of nearby and
distant SN Ia. We find no difference in the measures we describe here. In this
paper, we base our analysis solely on line-profile morphology, focusing on
measurements of the velocity location of maximum absorption (vabs) and peak
emission (vpeak). We find that the evolution of vabs and vpeak for our sample
lines (Ca II 3945, Si II 6355, and S II 5454, 5640) is similar for both the
low- and high-redshift samples. We find that vabs for the weak S II 5454, 5640
lines, and vpeak for S II 5454, can be used to identify fast-declining [dm15 >
1.7] SN Ia, which are also subluminous. In addition, we give the first direct
evidence in two high-z SN Ia spectra of a double-absorption feature in Ca II
3945, an event also observed, though infrequently, in low-redshift SN Ia
spectra (6/22 SN Ia in our local sample). We report for the first time the
unambiguous and systematic intrinsic blueshift of peak emission of optical
P-Cygni line profiles in Type Ia spectra, by as much as 8000 km/s. All the
high-z SN Ia analyzed in this paper were discovered and followed up by the
ESSENCE collaboration, and are now publicly available.Comment: 28 pages (emulateapj), 15 figures; accepted for publication in A
A Study of Carbon Features in Type Ia Supernova Spectra
One of the major differences between various explosion scenarios of Type Ia
supernovae (SNe Ia) is the remaining amount of unburned (C+O) material and its
velocity distribution within the expanding ejecta. While oxygen absorption
features are not uncommon in the spectra of SNe Ia before maximum light, the
presence of strong carbon absorption has been reported only in a minority of
objects, typically during the pre-maximum phase. The reported low frequency of
carbon detections may be due to low signal-to-noise data, low abundance of
unburned material, line blending between C II 6580 and Si II 6355, ejecta
temperature differences, asymmetrical distribution effects, or a combination of
these. However, a survey of published pre-maximum spectra reveals that more SNe
Ia than previously thought may exhibit C II 6580 absorption features and relics
of line blending near 6300 Angstroms. Here we present new SN Ia observations
where spectroscopic signatures of C II 6580 are detected, and investigate the
presence of C II 6580 in the optical spectra of 19 SNe Ia using the
parameterized spectrum synthesis code, SYNOW. Most of the objects in our sample
that exhibit C II 6580 absorption features are of the low-velocity gradient
subtype. Our study indicates that the morphology of carbon-rich regions is
consistent with either a spherical distribution or a hemispheric asymmetry,
supporting the recent idea that SN Ia diversity may be a result of off-center
ignition coupled with observer line-of-sight effects.Comment: 10 papges, 9 figures, 3 table
Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in murine models of inherited blindness. However, humans depend more upon cone photoreceptors that are required for daylight, color, and high-acuity vision. Indeed, macular retinopathies involving loss of cones are leading causes of blindness. An essential step for developing stem cell-based therapies for maculopathies is the ability to generate transplantable human cones from renewable sources. Here, we report a modified 2D/3D protocol for generating hPSC-derived neural retinal vesicles with well-formed ONL-like structures containing cones and rods bearing inner segments and connecting cilia, nascent outer segments, and presynaptic structures. This differentiation system recapitulates human photoreceptor development, allowing the isolation and transplantation of a pure population of stage-matched cones. Purified human long/medium cones survive and become incorporated within the adult mouse retina, supporting the potential of photoreceptor transplantation for treating retinal degeneration
Assessment of rotatory laxity in anterior cruciate ligament-deficient knees using magnetic resonance imaging with Porto-knee testing device
Purpose Objective evaluation of both antero-posterior
translation and rotatory laxity of the knee remains a target
to be accomplished. This is true for both preoperative
planning and postoperative assessment of different ACL
reconstruction emerging techniques. The ideal measurement tool should be simple, accurate and reproducible,
while enabling to assess both ‘‘anatomy’’ and ‘‘function’’
during the same examination. The purpose of this study is
to evaluate the clinical effectiveness of a new in-housedeveloped testing device, the so-called Porto-knee testing
device (PKTD). The PKTD is aimed to be used on the
evaluation of both antero-posterior and rotatory laxity of
the knee during MRI exams.
Methods Between 2008 and 2010, 33 patients with ACLdeficient knees were enrolled for the purpose of this study.
All patients were evaluated in the office and under
anesthesia with Lachman test, lateral pivot-shift test and
anterior drawer test. All cases were studied preoperatively
with KT-1000 and MRI with PKTD, and examinations
performed by independent observers blinded for clinical
evaluation. During MRI, we have used a PKTD that applies
antero-posterior translation and permits free tibial rotation
through a standardized pressure (46.7 kPa) in the proximal
posterior region of the leg. Measurements were taken for
both knees and comparing side-to-side. Five patients with
partial ruptures were excluded from the group of 33.
Results For the 28 remaining patients, 3 women and 25
men, with mean age of 33.4 ± 9.4 years, 13 left and 15 right
knees were tested. No significant correlation was noticed for
Lachman test and PKTD results (n.s.). Pivot-shift had a
strong positive correlation with the difference in anterior
translation registered in lateral and medial tibia plateaus of
injured knees (cor. coefficient = 0.80; p\0.05), and with
the difference in this parameter as compared to side-to-side
(cor. coefficient = 0.83; p\0.05).
Considering the KT-1000 difference between injured and
healthy knees, a very strong positive correlation was found
for side-to-side difference in medial (cor. coeffi-
cient = 0.73; p\0.05) and lateral (cor. coefficient = 0.5;
p\0.05) tibial plateau displacement using PKTD.
Conclusion The PKTD proved to be a reliable tool in
assessment of antero-posterior translation (comparing with
KT-1000) and rotatory laxity (compared with lateral pivotshift under anesthesia) of the ACL-deficient knee during
MRI examinatio
ACL injuries identifiable for pre-participation imagiological analysis: Risk factors
Identification of pre-participation risk factors for noncontact anterior cruciate ligament (ACL) injuries has been attracting a great deal of interest in the sports medicine and traumatology communities. Appropriate methods that enable predicting which patients could benefit from pre- ventive strategies are most welcome. This would enable athlete-specific training and conditioning or tailored equipment in order to develop appropriate strategies to reduce incidence of injury. In order to accomplish these goals, the ideal system should be able to assess both anatomic and functional features. Complementarily, the screening method must be cost-effective and suited for widespread application. Anatomic study protocol requiring only standard X rays could answer some of such demands. Dynamic MRI/CT evaluation and electronically assisted pivot-shift evaluation can be powerful tools providing complementary information. These upcoming insights, when validated and properly combined, envision changing pre-participation knee examination in the near future. Herein different methods (validated or under research) aiming to improve the capacity to identify persons/athletes with higher risk for ACL injury are overviewed.
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