Synthesis, characterization and crystal structure of N'-[(E)-furan-2-ylmethylidene]furan-2-carbohydrazide

A new compound, N'-[(E)-furan-2-ylmethylidene]furan-2-carbohydrazide was synthesized. Elemental analysis, IR spectrum, 1H NMR and X-ray crystal structure studies were carried out to determine the compositions and molecular structure of the compound. It crystallizes in the orthorhombic space group Pbca with unit cell parameters a = 11.3142(4) Å, b = 7.5526(2) Å and c = 22.9030(9) Å. The crystal structure studies reveal intermolecular N-H···O hydrogen bonding interactions in the solid state

Synthesis, characterization and antimicrobial studies of novel schiff bases and their complexes

Novel Schiff bases, Furan-2-carboxylic acid pyridin-4-ylmethyleneamide (L1), and Thiophene-2-carboxylic acid 1H-indol-2-ylmethyleneamide (L­2) and their mononuclear Ni(II) and Cu(II) complexes have been synthesized and characterized by elemental analysis, molar conductance, UV-Vis, FT-IR, 1H NMR and EPR spectroscopy. The complexes are non-electrolytes. The ligands and their complexes have been tested for their antimicrobial activity against one Gram positive bacteria, Bacillus subtilis, one Gram negative bacteria, Escherichia coli and fungi Candida albicans. It was found that metal complexes exhibited more activity than the free ligand

Synthesis, characterization and antimicrobial studies of novel Schiff bases and their complexes

538-544Novel Schiff bases, Furan-2-carboxylic acid pyridin-4-ylmethyleneamide , and Thiophene-2-carboxylic acid 1H-indol-2-ylmethyleneamide and their mononuclear Ni(II) and Cu(II) complexes have been synthesized and characterized by elemental analysis, molar conductance, UV-visible, FT-IR, 1H NMR and EPR spectroscopy. The complexes are non-electrolytes as evidenced from the molar conductance vaules. The ligands and their complexes have been tested for their antimicrobial activity against one gram positive bacteria, Bacillus subtilis, gram negative bacteria, Escherichia coli and fungi Candida albicans. It is found that metal complexes exhibited more activity than the free ligand

Biologically Important Schiff Bases and Their Transition Metal Complexes

Transition metal complexes with different ligand systems have been developed. Majority of them are derived from heteroaromatic cycles and Schiff bases of variety of aromatic aldehydes, diketones with amino acids, polyamines, N-aromatic cycles and ethylenediamines. Metal complexes of Schiff bases are used as polymers, dyes and in various biological systems. They show antimicrobial activity and can be used as suitable drug to treat bacterial and fungal infections. Most of the Cu, Ni and Co complexes are also capable of binding and cleaving DNA

A Design of Digital Microfluidic Biochip along with Structural and Behavioural Features in Triangular Electrode Based Array

AbstractDigital microfluidic based biochip manoeuvres on the theory of microfluidic technology, having a broad variety of applications in chemistry, biology, environmental monitoring, military etc. Being concerned about the technological advancement in this domain, we have focused on equilateral triangular electrodes based DMFB systems. Accepting the associated design issues, here, we have addressed many facets of such electrodes regarding their structural and behavioural issues in comparison to the existing square electrodes. As the requisite voltage reduction is a key challenging design issues, to implement all the tasks using triangular electrodes that are possible in square electrode arrays as well, is a tedious job. Furthermore, to deal with this new design deploying triangular electrodes, we have analyzed all the necessary decisive factors including fluidic constraints to ensure safe droplet movements and other modular operations together with mixing and routing. Moreover, an algorithm has been developed to find a route for a given source and destination pair in this newly designed DMFB. Finally, we have included a comparative study between this new design and the existing one while encountering the above mentioned issues

Synthesis, X-ray structure and catalytic properties of a copper(II) Schiff base complex modeling the activity of the Cu-B site of dopamine beta-hydroxylase

The copper(II) complex [Cu(salgly) (bpy)] . 4H(2)O (1), where salgly is a tridentate glycinatosalicylaldimine Schiffbase Ligand, is prepared and structurally characterized. The complex is found to be catalytically active in the oxidation of ascorbic acid by dioxygen and the process is also effective in the presence of benzylamine giving benzaldehyde as a product, thus modeling the activity of the Cu-B site of dopamine beta-hydroxylase. (C) 2000 Elsevier Science S.A. All rights reserved

N′-[(E)-Furan-2-ylmethylidene]-4-hydroxybenzohydrazide

The title compound, C12H10N2O3, exists in the E conformation. The five-membered ring and the phenyl rings form dihedral angles of 36.73 (10) and 12.22 (10)°, respectively, with the central C(=O)N2C unit. The crystal packing is dominated by strong N—H...O and O—H...N hydrogen bonds. Together with weaker C—H...O interactions, these establish a three-dimensional supramolecular network

4-{(E)-[2-(Pyridin-3-ylcarbonyl)hydrazinylidene]methyl}phenyl acetate

The title compound, C15H13N3O3, exists in the E conformation with respect to the azomethane C=N double bond. The pyridyl and phenyl rings form dihedral angles of 35.67 (8) and 36.65 (7)°, respectively with the central C(=O)N2C unit. In the crystal, N—H...O and C—H...O hydrogen bonds connect the molecules into chains along the b axis. Another C—H...O interaction connects molecules along the c-axis direction, forming layers

Crystal structure of 4-{(E)-[2-(pyridin-4-ylcarbonyl)hydrazin-1-ylidene]methyl}phenyl acetate monohydrate

The asymmetric unit of the title compound, C15H13N3O3·H2O, comprises a 4-{(E)-[2-(pyridin-4-ylcarbonyl)hydrazinylidene]methyl}phenyl acetate molecule and a solvent water molecule linked by O—H...O and O—H...N hydrogen bonds from the water molecule and a C—H...O contact from the organic molecule. The compound adopts an E conformation with respect to the azomethine bond and the dihedral angle between the pyridine and benzene rings is 21.90 (7)°. The azomethine bond [1.275 (2) Å] distance is very close to the formal C=N bond length, which confirms the azomethine bond formation. An extensive set of O—H...O, O—H...N, N—H...O and C—H...O hydrogen bonds builds a two-dimensional network progressing along the c axis