183 research outputs found

    Systems training and development of personnel at the oil and gas companies

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    Training is a process of development of specific skills through special training methods. Staff training ensures professional knowledge and skills of modern production requirements. Modern business is growing, the competition grows, and as a result, organizations need to make more efforts to develop rapidly and be successful. This fact began to realize by progressive Russian oil and gas companies, which are increasingly focused on the creation of professional personnel management system. Training systems currently used by most major oil and gas companies. This allows enterprises to successfully exist in a competitive environment. The article describes the system of training and staff development. Obtained system of training in the workplace and outside it. Presents the advantages and disadvantages of systems

    Design White label IPTV application for Apple TV platform

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    Analysis of IPTV/OTT system of β€œTelebreeze Corporation” company was done and general structure of this system was reviewed. β€œWhite label” application for Apple TV was designed and his place in the β€œTelebreeze Corporation” system was described

    B cell activation and proliferation increase intracellular zinc levels

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    Zinc ions serve as second messengers in major cellular pathways, including the regulation pathways of proliferation and their proper regulation is necessary for homeostasis and a healthy organism. Accordingly, expression of zinc transporters can be altered in various cancer cell lines and is often involved in producing elevated intracellular zinc levels. In this study, human B cells were infected with Epstein–Barr virus (EBV) to generate immortalized cells, which revealed traits of tumor cells, such as high proliferation rates and an extended lifespan. These cells showed differentially altered zinc transporter expression with ZIP7 RNA and protein expression being especially increased as well as a corresponding increased phosphorylation of ZIP7 in EBV-transformed B cells. Accordingly, free zinc levels were elevated within these cells. To prove whether the observed changes resulted from immortalization or rather high proliferation, free zinc levels in in vitro activated B cells and in freshly isolated B cells expressing the activation marker CD69 were determined. Here, comparatively increased zinc levels were found, suggesting that activation and proliferation, but not immortalization, act as crucial factors for the elevation of intracellular free zinc

    О Ρ‡Π΅ΠΌ ΠΏΠΎΠ²Π΅Π΄Π°Π» Π°Ρ€Ρ…ΠΈΠ² ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΡƒΡ‡Π΅Π½ΠΎΠ³ΠΎ-политСхника…

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    Bir tΓΆvbekar

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    Ahmet Mithat'Δ±n TercΓΌman-Δ± Hakikat'te tefrika edilen Bir TΓΆvbekar adlΔ± roman

    ΠžΠΏΡ‚ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΡ условий экстрагирования ΠΌΠ΅Π»Π°Π½ΠΈΠ½ΠΎΠ² ΠΈΠ· Π»ΡƒΠ·Π³ΠΈ подсолнСчника

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    ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΎΠΏΡ‚ΠΈΠΌΠ°Π»ΡŒΠ½Ρ‹Π΅ значСния ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€ΠΎΠ² экстрагирования ΠΌΠ΅Π»Π°Π½ΠΈΠ½ΠΎΠ² ΠΈΠ· Π»ΡƒΠ·Π³ΠΈ подсолнСчника: частота Π²ΠΈΠ±Ρ€Π°Ρ†ΠΈΠΉ 24 Π“Ρ†, концСнтрация раствора гидроксида натрия 0,36 М, 3 ступСни экстрагирования, ΠΏΡ€ΠΎΠ΄ΠΎΠ»ΠΆΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ экстрагирования Π½Π° ΠΊΠ°ΠΆΠ΄ΠΎΠΉ ступСни 20 ΠΌΠΈΠ½ΡƒΡ‚. Π’Ρ‹Ρ…ΠΎΠ΄ ΠΌΠ΅Π»Π°Π½ΠΈΠ½ΠΎΠ² ΠΏΡ€ΠΈ Π΄Π°Π½Π½Ρ‹Ρ… условиях составил 13,09%. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Π΄Π°Π½Π½Ρ‹Π΅ ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Π½Ρ‹ ΠΏΡ€ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ получСния ΠΌΠ΅Π»Π°Π½ΠΈΠ½Π° ΠΈΠ· Π°Π»ΡŒΡ‚Π΅Ρ€Π½Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΡ‹Ρ€ΡŒΡ - Π»ΡƒΠ·Π³ΠΈ подсолнСчника.Defined are the optimal values of the parameters extraction of melanin from the husks of sunflower: the vibration frequency 24 Hz, the concentration of sodium hydroxide solution 0,36 M, 3 stages of extraction, duration of extraction at each stage in 20 minutes. The degree of extraction of melanin under these conditions were 13,09%. The results obtained determine the possibility of development of technology for production melanines from alternative raw materials - sunflower husk

    ΠšΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½Ρ‹Π΅ гСофизичСскиС исслСдования с Ρ†Π΅Π»ΡŒΡŽ ΠΎΡ†Π΅Π½ΠΊΠΈ тСхничСского состояния скваТин Π½Π° Бамотлорском Π½Π΅Ρ„Ρ‚Π΅Π³Π°Π·ΠΎΠ²ΠΎΠΌ мСстороТдСнии (Π₯Π°Π½Ρ‚Ρ‹-Мансийский Π°Π²Ρ‚ΠΎΠ½ΠΎΠΌΠ½Ρ‹ΠΉ ΠΎΠΊΡ€ΡƒΠ³)

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    ΠŸΡ€ΠΎΠ΅ΠΊΡ‚ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ комплСкса промыслово-гСофизичСских исслСдований Π½Π° Бамотлорсокм мСстороТдСнии для скваТины, которая находится послС Ρ€Π΅ΠΌΠΎΠ½Ρ‚Π°. Π—Π°ΠΏΡ€ΠΎΠ΅ΠΊΡ‚ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹ΠΉ комплСкс Ρ€Π΅ΡˆΠ°Π΅Ρ‚ Π·Π°Π΄Π°Ρ‡Ρƒ, ΠΏΡ€ΠΎΠ²Π΅Ρ€ΠΊΠ° тСхничСского состояния ΠΊΠΎΠ½Π΄ΡƒΠΊΡ‚ΠΎΡ€Π° Π² ΠΈΠ½Ρ‚Π΅Ρ€Π²Π°Π»Π΅ 100-250 ΠΌΠ΅Ρ‚Ρ€ΠΎΠ².Design of a complex of trade geophysical surveys on Samotlorsokm the field for the well which is after repair. The designed complex has to solve a problem, check of technical condition of the conductor in the range of 100-250 meters

    Π—ΠΠ‘Π’ΠžΠ‘Π£Π’ΠΠΠΠ― Π’ Π‘Π₯Π•ΠœΠΠ₯ ЗБАГАЧЕННЯ Π’ΠžΠΠšΠžΠŸΠžΠ”Π Π†Π‘ΠΠ•ΠΠžΠ‡ Π‘Π˜Π ΠžΠ’Π˜ΠΠ˜ Π£Π”ΠžΠ‘ΠšΠžΠΠΠ›Π•ΠΠžΠ“Πž ΠœΠΠ“ΠΠ†Π’ΠΠžΠ“Πž Π“Π†Π”Π ΠžΠ¦Π˜ΠšΠ›ΠžΠΠ£

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    ΠŸΡ€ΠΎΠ±Π»Π΅ΠΌΠ° Ρ‚Π° Ρ—Ρ— Π·Π²'язок Π· Π½Π°ΡƒΠΊΠΎΠ²ΠΈΠΌΠΈ Ρ– ΠΏΡ€Π°ΠΊΡ‚ΠΈΡ‡Π½ΠΈΠΌΠΈ Π·Π°Π΄Π°Ρ‡Π°ΠΌΠΈ. НСобхідна ΡΡ‚ΡƒΠΏΡ–Π½ΡŒ подрібнСння Ρ€ΡƒΠ΄ΠΈ ΠΏΠ΅Ρ€Π΅Π΄ Ρ—Ρ— пСрСроблСнням Π²ΠΈΠ·Π½Π°Ρ‡Π°Ρ”Ρ‚ΡŒΡΡ Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΎΠΌ вкраплСння Ρ€ΡƒΠ΄Π½ΠΈΡ… ΠΌΡ–Π½Π΅Ρ€Π°Π»Ρ–Π², використанням Ρ€Ρ–Π·Π½ΠΈΡ… ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ–Π² збагачСння сиро-Π²ΠΈΠ½ΠΈ, Π²ΠΈΠΌΠΎΠ³Π°ΠΌΠΈ Π΄ΠΎ якості ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ‚Ρ–Π², ΠΏΠΎΡΠ»Ρ–Π΄ΠΎΠ²Π½Ρ–ΡΡ‚ΡŽ Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½ΠΈΡ… процСсів, Ρ‰ΠΎ Π·Π°ΡΡ‚ΠΎΡΠΎΠ²ΡƒΡŽΡ‚ΡŒΡΡ Ρƒ схСмах ΠΏΠ΅Ρ€Π΅Ρ€ΠΎΠ±ΠΊΠΈ корисних ΠΊΠΎΠΏΠ°Π»ΠΈΠ½. Π§ΠΈΠΌ Ρ‚ΠΎΠ½ΡˆΠ΅ ΠΊΡ–Π½Ρ†Π΅Π²Π° ΠΊΡ€ΡƒΠΏΠ½Ρ–ΡΡ‚ΡŒ подрібнСння Ρ€ΡƒΠ΄ΠΈ, Ρ‚ΠΈΠΌ мСншС Π·Π°Π»ΠΈΡˆΠ°Ρ”Ρ‚ΡŒΡΡ ΠΌΡ–Π½Π΅Ρ€Π°Π»ΡŒΠ½ΠΈΡ… зростків Ρ– Ρ‚ΠΈΠΌ Π±Ρ–Π»ΡŒΡˆΠ΅ Π²Ρ–Ρ€ΠΎΠ³Ρ–Π΄Π½Ρ–ΡΡ‚ΡŒ отримання якісних ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ‚Ρ–Π²

    ИсслСдованиС каталитичСской активности мСталличСских ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ², ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… элСктроимпусными ΠΌΠ΅Ρ‚ΠΎΠ΄Π°ΠΌΠΈ, Π² синтСзС Π€ΠΈΡˆΠ΅Ρ€Π° Π’Ρ€ΠΎΠΏΡˆΠ°

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    Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдования каталитичСской активности мСталличСских ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ² Π’Πš6 ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΠ΅ΠΌΡ‹Ρ… Π² Ρ€ΠΎΠ»ΠΈ ΠΊΠ°Ρ‚Π°Π»ΠΈΠ·Π°Ρ‚ΠΎΡ€Π° Π² синтСзС Π€ΠΈΡˆΠ΅Ρ€Π°-Π’Ρ€ΠΎΠΏΡˆΠ°. Π˜ΡΠΏΡ‹Ρ‚Π°Π½ΠΈΡ Π±Ρ‹Π»ΠΈ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Ρ‹ Π½Π° Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½ΠΎΠΉ установкС, Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Π½Π½ΠΎΠΉ ΠΈ ΠΈΠ·Π³ΠΎΡ‚ΠΎΠ²Π»Π΅Π½Π½ΠΎΠΉ Π—ΠΠž Β«ΠšΠ°Ρ‚Π°ΠΊΠΎΠ½Β», Π³.Новосибирск. Для получСния тонкодиспСрсных ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ² использовался ΠΌΠ΅Ρ‚ΠΎΠ΄ элСктроискрового диспСргирования Π² ΠΆΠΈΠ΄ΠΊΠΎΠΉ срСдС. Для изучСния Ρ„ΠΈΠ·ΠΈΠΊΠΎ-химичСских свойств ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ² использовались: ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Ρ‹ ΡƒΠ΄Π΅Π»ΡŒΠ½ΠΎΠΉ повСрхности частиц ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ² ΠΏΠΎ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρƒ Π‘Π­Π’, ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ растровой ΠΈ ΡΠΊΠ°Π½ΠΈΡ€ΡƒΡŽΡ‰Π΅ΠΉ элСктронной микроскопии, Π° Ρ‚Π°ΠΊΠΆΠ΅ Ρ€Π΅Π½Ρ‚Π³Π΅Π½ΠΎΡ„Π°Π·ΠΎΠ²ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°.The research effort presents the results of a studing catalytic activity of metal powders VK6 used as catalyst in the synthesis of Fischer-Tropsch. Tests were conducted on a laboratory installation, which was designed and manufactured by CJSC "Caticon", Novosibirsk. The method of electrospark dispersion in liquid medium was applied during obtaining a fine powder. To study the physico-chemical properties of the obtained powders were used for determination of the specific surface of particles of powders by BET method, methods of raster and scanning electron microscopy, and X-ray phase analysis

    S-thioallylation of proteins by the garlic defence substance allicin and its biological effects

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    A single clove of edible garlic (Allium sativum L.) of about 10β€―g produces up to 5β€―mg of allicin (diallylthiosulfinate), a thiol-reactive sulfur-containing defence substance that gives injured garlic tissue its characteristic smell. Allicin induces apoptosis or necrosis in a dose-dependent manner but biocompatible doses influence cellular metabolism and signalling cascades. Oxidation of protein thiols and depletion of the glutathione pool are thought to be responsible for allicin's physiological effects. Here, we studied the effect of allicin on post-translational thiol-modification in human Jurkat T-cells using shotgun LC-MS/MS analyses. We identified 332 proteins that were modified by S-thioallylation in the Jurkat cell proteome which causes a mass shift of 72β€―Da on cysteines. Many S-thioallylated proteins are highly abundant proteins, including cytoskeletal proteins tubulin, actin, cofilin, filamin and plastin-2, the heat shock chaperones HSP90 and HSPA4, the glycolytic enzymes GAPDH, ALDOA, PKM as well the protein translation factor EEF2. Allicin disrupted the actin cytoskeleton in murine L929 fibroblasts. Allicin stimulated the immune response by causing Zn2+ release from proteins and increasing the Zn2+-dependent IL-1-triggered production of IL-2 in murine EL-4 T-cells. Furthermore, allicin caused inhibition of enolase activity, an enzyme considered a cancer therapy target. In conclusion, our study revealed the widespread extent of S-thioallylation in the human Jurkat cell proteome and showed effects of allicin exposure on essential cellular functions of selected targets, many of which are targets for cancer therapy
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