Parity violation in low energy neutron deuteron scattering

Parity violating effects for low energy elastic neutron deuteron scattering are calculated for DDH and EFT-type of weak potentials in a Distorted Wave Born Approximation, using realistic hadronic strong interaction wave functions, obtained by solving three-body Faddeev equations in configuration space. The results of relation between physical observables and low energy constants can be used to fix low energy constants from experiments. Potential model dependencies of parity violating effects are discussed.Comment: version accepted for publication in Phys. Rev.

Can realistic nuclear interactions tolerate a resonant tetraneutron ?

The possible existence of four-neutron resonances close to the physical energy region is explored. Faddeev-Yakubovsky equations have been solved in configuration space using realistic nucleon-nucleon interaction models. Complex Scaling and Analytical Continuation in the Coupling Constant methods were used to follow the resonance pole trajectories, which emerge out of artificially bound tetraneutron states. The final pole positions for four-neutron states lie in the third energy quadrant with negative real energy parts and should thus not be physically observable.Comment: 10 pages, 6 figs, 2 tables. To be published in Phys. Rev.

Time Reversal Invariance Violation in Neutron Deuteron Scattering

Time reversal invariance violating (TRIV) effects for low energy elastic neutron deuteron scattering are calculated for meson exchange and EFT-type of TRIV potentials in a Distorted Wave Born Approximation, using realistic hadronic strong interaction wave functions, obtained by solving three-body Faddeev equations in configuration space. The relation between TRIV and parity violating observables are discussed

Three-neutron resonance trajectories for realistic interaction models

Three-neutron resonances are investigated using realistic nucleon-nucleon interaction models. The resonance pole trajectories are explored by first adding an additional interaction to artificially bind the three-neutron system and then gradually removing it. The pole positions for the three-neutron states up to J=5/2 are localized in the third energy quadrant-Im (E)<=0, Re (E)<=0-well before the additional interaction is removed. Our study shows that realistic nucleon-nucleon interaction models exclude any possible experimental signature of three-neutron resonances.Comment: 13 pages ; 8 figs ; 5 table

Time Reversal Invariance Violating and Parity Conserving effects in Neutron Deuteron Scattering

Time reversal invariance violating parity conserving effects for low energy elastic neutron deuteron scattering are calculated for meson exchange and EFT-type of potentials in a Distorted Wave Born Approximation, using realistic hadronic wave functions, obtained by solving three-body Faddeev equations in configuration space.Comment: There was a technical mistake in calculations due to singular behavior of Yukawa functions at short range. We corrected the integration algorithm. There were some typos which are corrected. arXiv admin note: text overlap with arXiv:1104.305

Description of 4^{4}He tetramer bound and scattering states

Faddeev-Yakubovski equations are solved numerically for 4He tetramer and trimer states using realistic helium-helium interaction models. We describe the properties of ground and excited states, and we discuss with a special emphasis the 4He-4He3 low energy scattering

Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome

Mutations in potassium and calcium channel genes have been associated with cardiac arrhythmias. Here, Jensen et al. show that an anion transporter chloride-bicarbonate exchanger AE3 is also responsible for the genetically-induced mechanism of cardiac arrhythmia, suggesting new therapeutic targets for this diseas

The ζ Toxin Induces a Set of Protective Responses and Dormancy

The ζε module consists of a labile antitoxin protein, ε, which in dimer form (ε2) interferes with the action of the long-living monomeric ζ phosphotransferase toxin through protein complex formation. Toxin ζ, which inhibits cell wall biosynthesis and may be bactericide in nature, at or near physiological concentrations induces reversible cessation of Bacillus subtilis proliferation (protective dormancy) by targeting essential metabolic functions followed by propidium iodide (PI) staining in a fraction (20–30%) of the population and selects a subpopulation of cells that exhibit non-inheritable tolerance (1–5×10−5). Early after induction ζ toxin alters the expression of ∼78 genes, with the up-regulation of relA among them. RelA contributes to enforce toxin-induced dormancy. At later times, free active ζ decreases synthesis of macromolecules and releases intracellular K+. We propose that ζ toxin induces reversible protective dormancy and permeation to PI, and expression of ε2 antitoxin reverses these effects. At later times, toxin expression is followed by death of a small fraction (∼10%) of PI stained cells that exited earlier or did not enter into the dormant state. Recovery from stress leads to de novo synthesis of ε2 antitoxin, which blocks ATP binding by ζ toxin, thereby inhibiting its phosphotransferase activity

17th Century Variola Virus Reveals the Recent History of Smallpox

Smallpox holds a unique position in the history of medicine. It was the first disease for which a vaccine was developed and remains the only human disease eradicated by vaccination. Although there have been claims of smallpox in Egypt, India, and China dating back millennia [1-4], the timescale of emergence of the causative agent, variola virus (VARV), and how it evolved in the context of increasingly widespread immunization, have proven controversial [4-9]. In particular, some molecular-clock-based studies have suggested that key events in VARV evolution only occurred during the last two centuries [4-6] and hence in apparent conflict with anecdotal historical reports, although it is difficult to distinguish smallpox from other pustular rashes by description alone. To address these issues, we captured, sequenced, and reconstructed a draft genome of an ancient strain of VARV, sampled from a Lithuanian child mummy dating between 1643 and 1665 and close to the time of several documented European epidemics [1, 2, 10]. When compared to vaccinia virus, this archival strain contained the same pattern of gene degradation as 20th century VARVs, indicating that such loss of gene function had occurred before ca. 1650. Strikingly, the mummy sequence fell basal to all currently sequenced strains of VARV on phylogenetic trees. Molecular-clock analyses revealed a strong clock-like structure and that the timescale of smallpox evolution is more recent than often supposed, with the diversification of major viral lineages only occurring within the 18th and 19th centuries, concomitant with the development of modern vaccination.Peer reviewe