12,672 research outputs found
Innovative Opportunities for Elementary and Middle School Teachers to Maintain Currency in Mathematics and Science: A Community College-School System Partnership
Since 1992 the Manassas Campus of Northern Virginia Community College – in response to requests from local school systems – has developed four innovative methods of assisting elementary, secondary and middle school teachers to enhance their content knowledge in science and mathematics, as well as integrate curriculum units for classroom presentation. These methods are based on the assumptions that: - While teachers at this level have fundamental understanding of math and science, if they wish to incorporate new concepts or technologies from these fields, graduate level content courses are generally beyond their background level. - Community College faculty can often provide a bridge that connects advanced content in science and mathematics with the applications that can be adapted to elementary/middle school curriculum. - Presenting content to a mixed audience of teachers from K-8 allows teachers to see how content can be adapted to grade levels above and below. - Content delivery methods must be interactive and must be responsive to the multiple demands on these teachers’ time. This requires flexibility in scheduling and course requirements
The occurrence of cadmium in seawater and in marine organisms and sediments
Methods have been developed for determining cadmium in seawater, marine organisms, and marine sediments. The procedure, based on the dithizone extraction method of Saltzman, is capable of detecting less than 10 mµg of the element and can be used for determining cadmium in silicate rocks; only thallium interferes. To confirm the presence of cadmium and to ensure freedom from contamination, the dithizone extracts were examined spectrographically
Multilayered printed circuit boards inspected by X-ray laminography
Technique produces high resolution cross-sectional radiographs with close interplane spacing for inspecting multilayer boards to be used in providing circuitry routing and module structural support
Correction: Molecular epidemiology of clostridium difficile infection in a large teaching hospital in Thailand
The third author’s name is spelled incorrectly. The correct name is: Papanin Putsathit. The correct citation is: Ngamskulrungroj P, Sanmee S, Putsathit P, Piewngam P, Elliott B, Riley TV, et al. (2015) Molecular Epidemiology of Clostridium difficile Infection in a Large Teaching Hospital in Thailand. PLoS ONE 10(5): e0127026. doi:10.1371/journal.pone.012702
Molecular epidemiology of Clostridium difficile infection in a large teaching hospital in Thailand
Clostridium difficile infection (CDI) is a leading cause of healthcare-associated morbidity and mortality worldwide. In Thailand, CDI exhibits low recurrence and mortality and its molecular epidemiology is unknown. CDI surveillance was conducted in a tertiary facility (Siriraj Hospital, Bangkok). A total of 53 toxigenic C. difficile strains from Thai patients were analyzed by multi-locus sequence typing (MLST), PCR ribotyping, and pulse-field gel electrophoresis (PFGE). The mean age of the cohort was 64 years and 62.3% were female; 37.7% of patients were exposed to > two antibiotics prior to a diagnosis of CDI, with beta-lactams the most commonly used drug (56.3%). Metronidazole was used most commonly (77.5%; success rate 83.9%), and non-responders were treated with vancomycin (success rate 100%). None of the isolates carried binary toxin genes. Most isolates (98.2-100%) were susceptible to metronidazole, vancomycin, tigecycline and daptomycin. There were 11 sequence types (STs), 13 ribotypes (RTs) and four PFGE types. Six previously identified STs (ST12, ST13, ST14, ST33, ST41 and ST45) and five novel STs unique to Thailand (ST66, ST67, ST68, ST69 and ST70) were identified. PCR RTs UK 017 (ST45) (45.3%) and UK 014/020 (ST33) (24.5%) were the most common. High concordance was observed between the MLST and ribotyping results (p<0.001). C. difficile isolates from Thai patients were highly susceptible to standard antimicrobial agents. In conclusion, the five STs indicate the high genetic diversity and unique polymorphisms in Thailand. Moreover, the emergence of antimicrobial resistance to vancomycin warranted continuous surveillance to prevent further spread of the toxigenic C. difficile isolates
Continuity equation and local gauge invariance for the N3LO nuclear Energy Density Functionals
Background: The next-to-next-to-next-to-leading order (N3LO) nuclear energy
density functional extends the standard Skyrme functional with new terms
depending on higher-order derivatives of densities, introduced to gain better
precision in the nuclear many-body calculations. A thorough study of the
transformation properties of the functional with respect to different
symmetries is required, as a step preliminary to the adjustment of the coupling
constants. Purpose: Determine to which extent the presence of higher-order
derivatives in the functional can be compatible with the continuity equation.
In particular, to study the relations between the validity of the continuity
equation and invariance of the functional under gauge transformations. Methods:
Derive conditions for the validity of the continuity equation in the framework
of time-dependent density functional theory. The conditions apply separately to
the four spin-isospin channels of the one-body density matrix. Results: We
obtained four sets of constraints on the coupling constants of the N3LO energy
density functional that guarantee the validity of the continuity equation in
all spin-isospin channels. In particular, for the scalar-isoscalar channel, the
constraints are the same as those resulting from imposing the standard U(1)
local-gauge-invariance conditions. Conclusions: Validity of the continuity
equation in the four spin-isospin channels is equivalent to the local-gauge
invariance of the energy density functional. For vector and isovector channels,
such validity requires the invariance of the functional under local rotations
in the spin and isospin spaces.Comment: 12 Latex pages, submitted to Physical Review
Kinetic theory model predictions compared with low-thrust axisymmetric nozzle plume data
A system of nonlinear integral equations equivalent to the steady-state Krook kinetic equation was used to model the flow from a low-thrust axisymmetric nozzle. The mathematical model was used to numerically calculate the number density, temperature, and velocity of a simple gas as it expands into a near vacuum. With these quantities the gas pressure and flow directions of the gas near the exit plane were calculated and compared with experimental values for a low-thrust nozzle of the same geometry and mass flow rate
The Whole Heliosphere Interval in the Context of a Long and Structured Solar Minimum: An Overview from Sun to Earth
Throughout months of extremely low solar activity during the recent extended solar-cycle minimum, structural evolution continued to be observed from the Sun through the solar wind and to the Earth. In 2008, the presence of long-lived and large low-latitude coronal holes meant that geospace was periodically impacted by high-speed streams, even though solar irradiance, activity, and interplanetary magnetic fields had reached levels as low as, or lower than, observed in past minima. This time period, which includes the first Whole Heliosphere Interval (WHI 1: Carrington Rotation (CR) 2068), illustrates the effects of fast solar-wind streams on the Earth in an otherwise quiet heliosphere. By the end of 2008, sunspots and solar irradiance had reached their lowest levels for this minimum (e.g., WHI 2: CR 2078), and continued solar magnetic-flux evolution had led to a flattening of the heliospheric current sheet and the decay of the low-latitude coronal holes and associated Earth-intersecting high-speed solar-wind streams. As the new solar cycle slowly began, solar-wind and geospace observables stayed low or continued to decline, reaching very low levels by June – July 2009. At this point (e.g., WHI 3: CR 2085) the Sun–Earth system, taken as a whole, was at its quietest. In this article we present an overview of observations that span the period 2008 – 2009, with highlighted discussion of CRs 2068, 2078, and 2085. We show side-by-side observables from the Sun’s interior through its surface and atmosphere, through the solar wind and heliosphere and to the Earth’s space environment and upper atmosphere, and reference detailed studies of these various regimes within this topical issue and elsewhere
Clostridium difficile ribotype 017 – characterization, evolution and epidemiology of the dominant strain in Asia
Clostridium difficile ribotype (RT) 017 is an important toxigenic C. difficile RT which, due to a deletion in the repetitive region of the tcdA gene, only produces functional toxin B. Strains belonging to this RT were initially dismissed as nonpathogenic and circulated largely undetected for almost two decades until they rose to prominence following a series of outbreaks in the early 2000s. Despite lacking a functional toxin A, C. difficile RT 017 strains have been shown subsequently to be capable of causing disease as severe as that caused by strains producing both toxins A and B. While C. difficile RT 017 strains can be found in almost every continent today, epidemiological studies suggest that the RT is endemic in Asia and that the global spread of this MLST clade 4 lineage member is a relatively recent event. C. difficile RT 017 transmission appears to be mostly from human to human with only a handful of reports of isolations from animals. An important feature of C. difficile RT 017 strains is their resistance to several antimicrobials and this has been documented as a possible factor driving multiple outbreaks in different parts of the world. This review summarizes what is currently known regarding the emergence and evolution of strains belonging to C. difficile RT 017 as well as features that have allowed it to become an RT of global importance
Comparative Recruitment Dynamics of Alewife and Bloater in Lakes Michigan and Huron
The predictive power of recruitment models often relies on the identification and quantification of external variables, in addition to stock size. In theory, the identification of climatic, biotic, or demographic influences on reproductive success assists fisheries management by identifying factors that have a direct and reproducible influence on the population dynamics of a target species. More often, models are constructed as one‐time studies of a single population whose results are not revisited when further data become available. Here, we present results from stock recruitment models for Alewife Alosa pseudoharengus and Bloater Coregonus hoyi in Lakes Michigan and Huron. The factors that explain variation in Bloater recruitment were remarkably consistent across populations and with previous studies that found Bloater recruitment to be linked to population demographic patterns in Lake Michigan. Conversely, our models were poor predictors of Alewife recruitment in Lake Huron but did show some agreement with previously published models from Lake Michigan. Overall, our results suggest that external predictors of fish recruitment are difficult to discern using traditional fisheries models, and reproducing the results from previous studies may be difficult particularly at low population sizes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141414/1/tafs0294.pd
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