17,048 research outputs found

    Effect of pretreatment of the state and reactivity of alumina-supported platinum-iridium catalysts

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    A systematic review of reported reassortant viral lineages of influenza A

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    BACKGROUND: Most previous evolutionary studies of influenza A have focussed on genetic drift, or reassortment of specific gene segments, hosts or subtypes. We conducted a systematic literature review to identify reported claimed reassortant influenza A lineages with genomic data available in GenBank, to obtain 646 unique first-report isolates out of a possible 20,781 open-access genomes. RESULTS: After adjusting for correlations, only: swine as host, China, Europe, Japan and years between 1997 and 2002; remained as significant risk factors for the reporting of reassortant viral lineages. For swine H1, more reassortants were observed in the North American H1 clade compared with the Eurasian avian-like H1N1 clade. Conversely, for avian H5 isolates, a higher number of reported reassortants were observed in the European H5N2/H3N2 clade compared with the H5N2 North American clade. CONCLUSIONS: Despite unavoidable biases (publication, database choice and upload propensity) these results synthesize a large majority of the current literature on novel reported influenza A reassortants and are a potentially useful prerequisite to inform further algorithmic studies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12879-015-1298-9) contains supplementary material, which is available to authorized users

    ‘But by blood no wolf am I’: Language and Agency, Instinct and Essence – Transcending Antinomies in Maggie Stiefvater’s Shiver trilogy

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    Young Adult dark romance is often more questioning than its adult counterpart; different, less constraining commercial imperatives are perhaps at work, or readers’ expectations less fixed. This chapter will show how, woven into a sensitive coming-of-age narrative of first love and familial problems, Maggie Stiefvater’s Shiver trilogy performs a far more sophisticated interrogation of the boundaries of animality and humanity than other such fictions, highlighting the centrality of language and its relationship to agency. The hero, Sam’s, struggle with his lupine nature becomes an existentialist refusal to be defined by nature; other characters are tempted instead to yield to a fatalistic surrender of will. The books are tantalisingly ambivalent about the appeal of the instinctual and the borderline between an embodied humanity and the animal, particularly as manifested in the love affair of the teenage protagonists. For Marcuse, the surplus-repression of the proximity senses (smell, taste) enforces the isolation of individuals in civilisation. Stiefvater continually emphasises the sense of smell both as a trigger to sexual attraction and as an aspect of the pack sociality and sense of belonging of the wolves. Through such devices, she concretely renders the nearness of Grace and Sam (her young lovers) to wolfhood. This is contrasted with her exploration of human subjectivity through language, particularly in the perceptive depiction of silences and miscommunications and her hero’s absorption in books and poetry

    Antimicrobial Susceptibilities of Aerobic Isolates from Respiratory Samples of Young New Zealand Horses

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    3rd Annual IEEE Energy Conversion Congress and Exposition, ECCE 2011, Phoenix, AZ, 17-22 September 2011This paper presents a method of mitigating the transient overshoots of DC-DC converters operating with large load disturbances. The method involves a small auxiliary power circuit with a complementary control scheme that provides a smooth absorption and release of excess energy from and to the main DC-DC converter in the events of large load changes. This control mechanism interactively mitigates the large transient overshoots which would otherwise appear at the converter output. Since the control scheme involves an adjustable-energy-storage feature, the proposed solution is effective for any level of step-load change within a pre-specified range.Department of Electronic and Information EngineeringRefereed conference pape

    The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model

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    Background. Nosocomial transmission of tuberculosis remains an important public health problem. We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and to evaluate environmental control measures. Methods. An animal facility was built above a mechanically ventilated HIV‐tuberculosis ward in Lima, Peru. A mean of 92 guinea pigs were continuously exposed to all ward exhaust air for 16 months. Animals had tuberculin skin tests performed at monthly intervals, and those with positive reactions were removed for autopsy and culture for tuberculosis. Results. Over 505 consecutive days, there were 118 ward admissions by 97 patients with pulmonary tuberculosis, with a median duration of hospitalization of 11 days. All patients were infected with HIV and constituted a heterogeneous group with both new and existing diagnoses of tuberculosis. There was a wide variation in monthly rates of guinea pigs developing positive tuberculin test results (0%–53%). Of 292 animals exposed to ward air, 159 developed positive tuberculin skin test results, of which 129 had laboratory confirmation of tuberculosis. The HIV‐positive patients with pulmonary tuberculosis produced a mean of 8.2 infectious quanta per hour, compared with 1.25 for HIV‐negative patients with tuberculosis in similar studies from the 1950s. The mean monthly patient infectiousness varied greatly, from production of 0–44 infectious quanta per hour, as did the theoretical risk for a health care worker to acquire tuberculosis by breathing ward air. Conclusions. HIV‐positive patients with tuberculosis varied greatly in their infectiousness, and some were highly infectious. Use of environmental control strategies for nosocomial tuberculosis is therefore a priority, especially in areas with a high prevalence of both tuberculosis and HIV infection

    Redundant Arrays of IDE Drives

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    The next generation of high-energy physics experiments is expected to gather prodigious amounts of data. New methods must be developed to handle this data and make analysis at universities possible. We examine some techniques that use recent developments in commodity hardware. We test redundant arrays of integrated drive electronics (IDE) disk drives for use in offline high-energy physics data analysis. IDE redundant array of inexpensive disks (RAID) prices now equal the cost per terabyte of million-dollar tape robots! The arrays can be scaled to sizes affordable to institutions without robots and used when fast random access at low cost is important. We also explore three methods of moving data between sites; internet transfers, hot pluggable IDE disks in FireWire cases, and writable digital video disks (DVD-R).Comment: Submitted to IEEE Transactions On Nuclear Science, for the 2001 IEEE Nuclear Science Symposium and Medical Imaging Conference, 8 pages, 1 figure, uses IEEEtran.cls. Revised March 19, 2002 and published August 200
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