12 research outputs found
Exfoliated malignant cells at the anastomosis site in colon cancer surgery: the impact of surgical bowel occlusion and intraluminal cleaning
Safety of fondaparinux to prevent venous thromboembolism in Japanese patients undergoing colorectal cancer surgery: a multicenter study
Recommended from our members
The effect of donor-specific transfusion and cyclosporin A on small bowel transplantation in the rat
Detection of Anorectal Cancer among Patients with Crohn's Disease Undergoing Surveillance with Various Biopsy Methods
Human papillomavirus infection is involved in the development of colonic squamous cell dysplasia in ulcerative colitis-associated carcinogenesis
Survival outcomes of appendiceal mucinous neoplasms by histological type and stage: Analysis of 266 cases in a multicenter collaborative retrospective clinical study
Abstract Aim Appendiceal mucinous neoplasms are rare, and thus the literature is sparse with regard to histological types, staging, and prognosis. In particular, it is unclear how longâterm outcome may differ between mucinous adenocarcinomas and other adenocarcinomas. In the present study, we aimed to investigate the histological types and stages of appendiceal neoplasms, and to evaluate the prognostic impacts of these factors in patients with mucinous adenocarcinomas and nonâmucinous adenocarcinomas. Methods Patients with appendiceal tumors diagnosed between 2007 and 2016 were retrospectively identified from the databases of 19 institutions in the Clinical Study Group of Osaka University, Colorectal Group. Results A total of 266 patients with appendiceal tumors were identified, of whom 130 had pathologically diagnosed adenocarcinomas, including 57 with mucinous adenocarcinomas and 73 with nonâmucinous adenocarcinomas. Fiveâyear overall survival (OS) rates were 64.5% for mucinous adenocarcinomas, and 49.0% for nonâmucinous adenocarcinomas. OS was significantly shorter among patients with nonâmucinous adenocarcinomas compared to mucinous adenocarcinomas. Among patients with mucinous adenocarcinomas, 5âyear OS rates were 53.6% for stage 0/I, 82.6% for II/III, and 48.4% for IV. Among patients with nonâmucinous adenocarcinomas, 5âyear OS rates were 90.9% for stage 0/I, 68.8% for II/III, and 7.1% for IV. Analysis of patients with stage IV disease revealed significantly shorter OS among patients with nonâmucinous adenocarcinomas compared to mucinous adenocarcinomas. Conclusion Our present findings showed a better prognosis in patients with mucinous adenocarcinomas compared to nonâmucinous adenocarcinomas. In this setting, Union for International Cancer Control staging was associated with prognosis for nonâmucinous adenocarcinomas, but not for mucinous adenocarcinomas