166 research outputs found

    CaracterĂ­sticas fĂ­sicas, quĂ­micas e anatĂŽmicas da madeira de Hovenia dulcis.

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    bitstream/CNPF-2009-09/30408/1/com_tec66.pd

    A proteomic evaluation of urinary changes associated with cardiopulmonary bypass

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    Additional file 4: Table S4. Correlation filtered 2D DDA/IDA and SWATH protein difference values

    Urinary, Plasma, and Serum Biomarkers’ Utility for Predicting Acute Kidney Injury Associated With Cardiac Surgery in Adults: A Meta-analysis

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    BackgroundEarly accurate detection of acute kidney injury (AKI) occurring after cardiac surgery may improve morbidity and mortality. Although several novel biomarkers have been developed for the early detection of AKI, their clinical utility in the critical intraoperative and immediate postoperative period remains unclear.Study DesignSystematic review and meta-analysis.Setting & PopulationAdult patients having cardiac surgery.Selection Criteria for StudiesEMBASE, CINAHL, Cochrane Library, Scopus, and PubMed from January 1990 until January 2015 were systematically searched for cohort studies reporting the utility of novel biomarkers for the early diagnosis of AKI after adult cardiac surgery. Reviewers extracted data for study design, population, timing of biomarker measurement and AKI occurrence, biomarker performance (area under the receiver operating characteristic curve [AUROC]), and risk of bias.Index TestsNovel urine, plasma, and serum AKI biomarkers, measured intraoperatively and in the early postoperative period (<24 hours).Reference TestsAKI was defined according to the RIFLE, AKIN, or 2012 KDIGO criteria.ResultsWe found 28 studies reporting intraoperative and/or early postoperative measurement of urine (n=23 studies) or plasma or serum (n=12 studies) biomarkers. Only 4 of these studies measured biomarkers intraoperatively. Overall, intraoperative discrimination by the urine biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury marker 1 (KIM-1) demonstrated AUROCs<0.70, whereas N-acetyl-ÎČ-d-glucosaminidase (NAG) and cystatin C had AUROCs<0.75. In the immediate 24-hour postoperative period, the urine biomarkers NGAL (16 studies), KIM-1 (6 studies), and liver-type fatty acid binding protein (6 studies) exhibited composite AUROCs of 0.69 to 0.72. The composite AUROCs for postoperative urine cystatin C, NAG, and interleukin 18 were ≀0.70. Similarly, the composite AUROCs for postoperative plasma NGAL (6 studies) and cystatin-C (5 studies) were <0.70.LimitationsHeterogeneous AKI definitions.ConclusionsIn adults, known urinary, plasma, and serum biomarkers of AKI possess modest discrimination at best when measured within 24 hours of cardiac surgery

    EVALUATION OF QUALITY OF PHENOLIC PLYWOOD MANUFACTURED FROM Eucalyptus grandis

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    A intensidade de dorm\ueancia e o requerimento em frio do vimeiro (Salix x rubens Shrank) foram avaliados pelo m\ue9todo de estacas de gema isolada. As observa\ue7\uf5es foram realizadas em ramos coletados em Lages, SC, a intervalos regulares de 21 dias, de 29/03/2004 a 2/08/2004. A brota\ue7\ue3o de gemas dos segmentos basal, mediano e distal de ramos do ano foi avaliada na aus\ueancia ou ap\uf3s suplementa\ue7\ue3o de frio (500 ou de 1000 horas a 5 \ub1 3\ub0C). A brota\ue7\ue3o de gemas foi avaliada nos est\ue1dios: a) gemas inchadas; b) in\uedcio da abertura das gemas; c) broto alongado e; d) broto alongado com folha aberta. A intensidade de dorm\ueancia das gemas foi crescente da base para a ponta dos ramos e foi m\ue1xima em 10 de maio, para todas as regi\uf5es do ramo. O tratamento com 500 horas de frio foi efetivo em reduzir o tempo para a brota\ue7\ue3o, em todas as \ue9pocas e posi\ue7\uf5es das gemas no ramo. A avalia\ue7\ue3o at\ue9 o aparecimento de folhas abertas foi importante para identificar a real capacidade de brota\ue7\ue3o das gemas.The dormancy intensity and chilling requirement of willow (Salix x rubens Shrank) were investigated in excised single node shoots. Observations were made from branches collected in Lages, Santa Catarina State, Brazil, at 21 days interval from March, 29th to August 2and, 2004. Budburst of buds from bottom, middle, and top segments of branches under natural chilled or completed with artificially chill by 500, and 1000 hours at 5\ub13\ub0C was evaluated. The sprouted were evaluated at wetting bud, expose bud; steam larded and opened leaf station. The most intensive dormancy occurred on May 10th and it was improved from the basal to top part of the branches. The chill treatment with 500 hours at 5\ub13\ub0C was effective in reducing the time to budburst. The real ability of bud development can be assessed only if observations are carried out until appearance of opened leaves

    Risk factors of post renal transplant anaemia among Sudanese patients, a study in three renal transplant centres

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    <p>Abstract</p> <p>Background</p> <p>There is a relative lack of recent information about late post kidney transplantation anaemia (PTA), especially in the developing countries; data are scarce about the prevalence and risk factors of PTA. Sudan was a leading country in Africa and Arab world in kidney transplantation. The first kidney transplantation in Sudan was in 1973.</p> <p>Methods</p> <p>This is a cross-sectional hospital analytic study enrolling all kidney transplanted recipients following in the transplant referral clinics at Ahmed Gassim, Selma and Ibn Sina Hospitals, Khartoum/Sudan, in the period from 1/8/2010 to 1/9/2010, clinical and laboratory data were obtained from 114 patients, anaemia was defined as Hb levels of < 13 g/dl for male patients and < 12 g/dl for female patients, exclusion criteria were pregnancy, below 18 years old patients, multiple organ transplantation, and patients with less than one year from the transplantation.</p> <p>Results</p> <p>The study showed that 39.5% of the patients were anaemic. Univariate analysis showed that late PTA is significantly associated with not using Erythropoietin (EPO) in the pre-transplant period (p = < 0.001), history of rejection (p = 0.003), longer time from transplantation (p = 0.015), and eGFR (p < 0.0001). Multivariate analysis showed that eGFR (p = < 0.001) and not use of EPO in the pre transplant period (p < 0.001) are strong predictors of PTA. The use of Angiotensin converting enzyme inhibitors/Angiotensin receptors blockers (ACEI/ARB), immunosuppressive treatments, presence or absence of co-morbidities, donor type and donor age are not significantly associated with late PTA.</p> <p>Conclusion</p> <p>The study concluded that late PTA is common and under recognized. Risk factors for late PTA include renal dysfunction, history of rejection, longer duration of transplantation and not using EPO in the pre-transplant period. Renal dysfunction and not using EPO in the pre-transplant period are major predictors of late PTA.</p
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