282 research outputs found
Cyber Space Odyssey: A Competitive, Team-Oriented Serious Game in Computer Networking
Cyber Space Odyssey (CSO) is a novel serious game supporting computer networking education by engaging students in a race to successfully perform various cybersecurity tasks in order to collect clues and solve a puzzle in virtual near-Earth 3D space. Each team interacts with the game server through a dedicated client presenting a multimodal interface, using a game controller for navigation and various desktop computer networking tools of the trade for cybersecurity tasks on the game\u27s physical network. Specifically, teams connect to wireless access points, use packet monitors to intercept network traffic, decrypt and reverse engineer that traffic, craft well-formed and meaningful responses, and transmit those responses. Successful completion of these physical network actions to solve a sequence of increasingly complex problems is necessary to progress through the virtual, story-driven adventure. Use of the networking tools reinforces networking theory and offers hands-on practical training requisite for today\u27s cyberoperators. This paper presents the learning outcomes targeted by a classroom intervention based on CSO, the design and implementation of the game, a pedagogical overview of the overall intervention, and four years of quantitative and qualitative data assessing its effectiveness
Data analysis of gravitational-wave signals from spinning neutron stars. III. Detection statistics and computational requirements
We develop the analytic and numerical tools for data analysis of the
gravitational-wave signals from spinning neutron stars for ground-based laser
interferometric detectors. We study in detail the statistical properties of the
optimum functional that need to be calculated in order to detect the
gravitational-wave signal from a spinning neutron star and estimate its
parameters. We derive formulae for false alarm and detection probabilities both
for the optimal and the suboptimal filters. We assess the computational
requirements needed to do the signal search. We compare a number of criteria to
build sufficiently accurate templates for our data analysis scheme. We verify
the validity of our concepts and formulae by means of the Monte Carlo
simulations. We present algorithms by which one can estimate the parameters of
the continuous signals accurately.Comment: LaTeX, 45 pages, 13 figures, submitted to Phys. Rev.
Reflections on Teaching and Learning in Field Education: A Teacher-Scholar Model
The purpose of this brief article is to report an innovative attempt to promote high quality field education utilizing Specialized Field Education Units (SFEUs) while overcoming both the internal and external barriers noted above. This approach, an integrated field unit using a teacher-scholar model, has been implemented for the past five years by the joint field education programs of the North Carolina Agricultural and Technical State University and the University of North Carolina at Greensboro BSW and MSW programs. The results have been a higher level of full-time engagement in field education by full-time tenure-track faculty members, high student success as measured by achievement of CSWE competencies, and higher rates of faculty publication and funding for research programs
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Novel failure analysis techniques using photon probing with a scanning optical microscope
Three new failure analysis techniques for integrated circuits (ICs) have been developed using localized photon probing with a scanning optical microscope (SOM). The first two are light-induced voltage alteration (LIVA) imaging techniques that (1) localize open-circuited and damaged junctions and (2) image transistor logic states. The third technique uses the SOM to control logic states optically from the IC backside. LIVA images are produced by monitoring the voltage fluctuations of a constant current power supply as a laser beam is scanned over the IC. High selectivity for localizing defects has been demonstrated using the LIVA approach. Logic state mapping results, similar to previous work using biased optical beam induced current (OBIC) and laser probing approaches have also been produced using LIVA. Application of the two LIVA based techniques to backside failure analysis has been demonstrated using an infrared laser source. Optical logic state control is based upon earlier work examining transistor response to photon injection. The physics of each method and their applications for failure analysis are described
Nanohertz Frequency Determination for the Gravity Probe B HF SQUID Signal
In this paper, we present a method to measure the frequency and the frequency
change rate of a digital signal. This method consists of three consecutive
algorithms: frequency interpolation, phase differencing, and a third algorithm
specifically designed and tested by the authors. The succession of these three
algorithms allowed a 5 parts in 10^10 resolution in frequency determination.
The algorithm developed by the authors can be applied to a sampled scalar
signal such that a model linking the harmonics of its main frequency to the
underlying physical phenomenon is available. This method was developed in the
framework of the Gravity Probe B (GP-B) mission. It was applied to the High
Frequency (HF) component of GP-B's Superconducting QUantum Interference Device
(SQUID) signal, whose main frequency fz is close to the spin frequency of the
gyroscopes used in the experiment. A 30 nHz resolution in signal frequency and
a 0.1 pHz/sec resolution in its decay rate were achieved out of a succession of
1.86 second-long stretches of signal sampled at 2200 Hz. This paper describes
the underlying theory of the frequency measurement method as well as its
application to GP-B's HF science signal.Comment: The following article has been submitted to Review of Scientific
Instruments. After it is published, it will be found at (http://rsi.aip.org/
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
The crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 Å using the semi-automated high-throughput pipeline of the Joint Center for Structural Genomics (JCSG) as part of the NIGMS Protein Structure Initiative (PSI). This protein structure is the first representative of the PF04016 (DUF364) Pfam family and reveals a novel combination of two well known domains (an enolase N-terminal-like fold followed by a Rossmann-like domain). Structural and bioinformatic analyses reveal partial similarities to Rossmann-like methyltransferases, with residues from the enolase-like fold combining to form a unique active site that is likely to be involved in the condensation or hydrolysis of molecules implicated in the synthesis of flavins, pterins or other siderophores. The genome context of Dhaf4260 and homologs additionally supports a role in heavy-metal chelation
The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.
Proteins that contain the DUF2874 domain constitute a new Pfam family PF11396. Members of this family have predominantly been identified in microbes found in the human gut and oral cavity. The crystal structure of one member of this family, BVU2987 from Bacteroides vulgatus, has been determined, revealing a β-lactamase inhibitor protein-like structure with a tandem repeat of domains. Sequence analysis and structural comparisons reveal that BVU2987 and other DUF2874 proteins are related to β-lactamase inhibitor protein, PepSY and SmpA_OmlA proteins and hence are likely to function as inhibitory proteins
Optical Magnetometry
Some of the most sensitive methods of measuring magnetic fields utilize
interactions of resonant light with atomic vapor. Recent developments in this
vibrant field are improving magnetometers in many traditional areas such as
measurement of geomagnetic anomalies and magnetic fields in space, and are
opening the door to new ones, including, dynamical measurements of bio-magnetic
fields, detection of nuclear magnetic resonance (NMR), magnetic-resonance
imaging (MRI), inertial-rotation sensing, magnetic microscopy with cold atoms,
and tests of fundamental symmetries of Nature.Comment: 11 pages; 4 figures; submitted to Nature Physic
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
The crystal structure of a putative NTPase, YP_001813558.1 from Exiguobacterium sibiricum 255-15 (PF09934, DUF2166) was determined to 1.78 Å resolution. YP_001813558.1 and its homologs (dimeric dUTPases, MazG proteins and HisE-encoded phosphoribosyl ATP pyrophosphohydrolases) form a superfamily of all-α-helical NTP pyrophosphatases. In dimeric dUTPase-like proteins, a central four-helix bundle forms the active site. However, in YP_001813558.1, an unexpected intertwined swapping of two of the helices that compose the conserved helix bundle results in a `linked dimer' that has not previously been observed for this family. Interestingly, despite this novel mode of dimerization, the metal-binding site for divalent cations, such as magnesium, that are essential for NTPase activity is still conserved. Furthermore, the active-site residues that are involved in sugar binding of the NTPs are also conserved when compared with other α-helical NTPases, but those that recognize the nucleotide bases are not conserved, suggesting a different substrate specificity
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