The Elementary and Secondary Education Act, as Amended by the No Child Left Behind Act: A Primer

[Excerpt] The primary source of federal aid to K-12 education is the Elementary and Secondary Education Act (ESEA), particularly its Title I, Part A program of Education for the Disadvantaged. The ESEA was initially enacted in 1965 (P.L. 89- 10), and was most recently amended and reauthorized by the No Child Left Behind Act of 2001 (NCLBA, P.L. 107-110). Virtually all ESEA programs are authorized through FY2008. During the current 110th Congress, congressional hearings are being conducted in anticipation of subsequent consideration of legislation to amend and extend the ESEA

Reorientation of the human body by means of arm motions

Arm motion effects on orientation of human body during free fall, and FORTRAN 4 program for solving equation

Synoptic observations of Jupiter's radio emissions: Average Statistical properties observed by Voyager

Observations of Jupiter's low frequency radio emissions collected over one month intervals before and after each Voyager encounter were analyzed. Compilations of occurrence probability, average power flux density and average sense of circular polarization are presented as a function of central meridian longitude, phase of Io, and frequency. The results are compared with ground based observations. The necessary geometrical conditions are preferred polarization sense for Io-related decametric emission observed by Voyager from above both the dayside and nightside hemispheres are found to be essentially the same as are observed in Earth based studies. On the other hand, there is a clear local time dependence in the Io-independent decametric emission. Io appears to have an influence on average flux density of the emission down to below 2 MHz. The average power flux density spectrum of Jupiter's emission has a broad peak near 9MHz. Integration of the average spectrum over all frequencies gives a total radiated power for an isotropic source of 4 x 10 to the 11th power W

Tropospheric gravity waves observed by three closely spaced ST radars

Clear-air radar experiments were carried out on the southern coast of France during the (ALPEX) Alpine experiment program vertically directed stratosphere-troposphere-radars were set up with spacings of about 5 to 6 km. The temporal and spectral characteristics of the vertical velocity fluctuations were examined. The horizontal and vertical properties of gravity waves in the lower atmosphere were analyzed. The techniques used and the first results from this wave study are described

Winter climate variability and snowpack in the West

Snowpack is an important source of water supply in the western United States. This study examines the seasonal variability of an extensive history of snow observations over the western United States and Canada. It links variations in snowpack to variations in atmospheric circulation, surface temperature, and precipitation

CLUSTERING A SERIES OF REPLICATED POLYPLOID GENE EXPRESSION EXPERIMENTS IN MAIZE

Ploidy level is defined as the number of individual sets of chromosomes contained in a single cell. Many important crop plants, such as potato, soybean and wheat are polyploid. Although it is widely known that polyploidy is a frequent evolutionary event, it is not fully understand why polyploids have been so successful. In this work cluster analysis is employed to study gene expression changes in a maize inbred line (B73) across a range of polyploidy levels. The B73 ploidy series includes monoploid, diploid, triploid and tetraploid plants and consists of biological and technical replicates as measured by microarray technology. An improved version of CORE (iCORE; improved Clustering of Repeat Expression) is presented to differentiate highly negatively correlated genes while taking advantage of the additional information that is provided by replication. The error information from the replicate experiments is utilized to cluster gene expression for both simulated and real ploidy-series data. Simulation results indicate that iCORE leads to an improvement in accuracy over both CORE and hierarchical clustering based on average gene expression only. When applied to the maize ploidy series, the iCORE results provide information that may aid in understanding of the effect of gene dose on gene expression in a ploidy series

Hyperinnervation Produces Inhibitory Interactions between Two Taste Nerves a

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74872/1/j.1749-6632.1987.tb43629.x.pd

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer

Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC). pCR in this setting is associated with improved EFS. Whether NCT preferentially improves EFS in comparison to NC followed by adjuvant trastuzumab initiated postoperatively (NCAT) has not been addressed. Using clinical data from women with HER2 positive BC treated at 7 European institutions between 2007 and 2010 we sought to investigate the impact on breast cancer outcomes of concomitant (NCT) versus sequential (NCAT) treatment in HER2 positive early BC. The unadjusted hazard ratio (HR) for event free survival with NCT compared with NCAT was 0.63 (95% CI 0.37–1.08; p = 0.091). Multivariable analysis revealed that treatment group, tumour size and ER status were significantly associated with EFS from diagnosis. In the whole group NCT was associated with a reduced risk of an event relative to NCAT, an effect that was confined to ER negative (HR: 0.25; 95% CI, 0.10–0.62; p = 0.003) as opposed to ER positive tumours (HR: 1.07; 95% CI, 0.46–2.52; p = 0.869). HER2 positive/ER negative BC treated with NC gain greatest survival benefit when trastuzumab is administered in both the neoadjuvant and adjuvant period rather than in the adjuvant period alone. These data support the early introduction of targeted combination therapy in HER2 positive/ER negative BC

Voyager spacecraft radio observations of Jupiter: Initial cruise results

Jupiter's low-frequency radio emission were detected by the planetary radio astronomy instruments onboard the two Voyager spacecraft. The emission is surprisingly similar in morphology but opposite in polarization to the high-frequency Jovian radio noise that were observed with ground-based telescopes for more than two decades. Several possible explanations for the behavior of the low-frequency emission are examined, but none of them is completely satisfactory