Ellipsoidal-mirror reflectometer accurately measures infrared reflectance of materials

Reflectometer accurately measures the reflectance of specimens in the infrared beyond 2.5 microns and under geometric conditions approximating normal irradiation and hemispherical viewing. It includes an ellipsoidal mirror, a specially coated averaging sphere associated with a detector for minimizing spatial and angular sensitivity, and an incident flux chopper

Spectral distribution of solar radiation

Available quantitative data on solar total and spectral irradiance are examined in the context of utilization of solar irradiance for terrestrial applications of solar energy. The extraterrestrial solar total and spectral irradiance values are also reviewed. Computed values of solar spectral irradiance at ground level for different air mass values and various levels of atmospheric pollution or turbidity are presented. Wavelengths are given for computation of solar, absorptance, transmittance and reflectance by the 100 selected-ordinate method and by the 50 selected-ordinate method for air mass 1.5 and 2 solar spectral irradiance for the four levels of atmospheric pollution

An immune reaction may be necessary for cancer development

BACKGROUND: The hypothesis of immunosurveillance suggests that new neoplasms arise very frequently, but most are destroyed almost at their inception by an immune response. Its correctness has been debated for many years. In its support, it has been shown that the incidences of many tumor types, though apparently not all, tend to be increased in immunodeficient animals or humans, but this observation does not end the debate. ALTERNATIVE MODEL: There is an alternative to the surveillance hypothesis; numerous studies have shown that the effect of an immune reaction on a tumor is biphasic. For each tumor, there is some quantitatively low level of immune reaction that, relative to no reaction, is facilitating, perhaps even necessary for the tumor's growth in vivo. The optimum level of this facilitating reaction may often be less than the level of immunity that the tumor might engender in a normal subject. CONCLUSION: The failure of a tumor to grow as well in the normal as it does in the immunosuppressed host is probably not caused by a lack of tumor-cell killing in the suppressed host. Instead, the higher level of immune response in a normal animal, even if it does not rise to tumor-inhibitory levels, probably gives less positive support to tumor growth. This seems more than a semantic distinction

The role of mutation in the new cancer paradigm

The almost universal belief that cancer is caused by mutation may gradually be giving way to the belief that cancer begins as a cellular adaptation that involves the local epigenetic silencing of various genes. In my own interpretation of the new epigenetic paradigm, the genes epigenetically suppressed are genes that normally serve in post-embryonic life to suppress and keep suppressed those other genes upon which embryonic development depends. Those other genes, if not silenced or suppressed in the post-embryonic animal, become, I suggest, the oncogenes that are the basis of neoplasia. Mutations that occur in silenced genes supposedly go unrepaired and are, therefore, postulated to accumulate, but such mutations probably play little or no causative role in neoplasia because they occur in already epigenetically silenced genes. These mutations probably often serve to make the silencing, and therefore the cancer, epigenetically irreversible

The Initial Immune Reaction to a New Tumor Antigen Is Always Stimulatory and Probably Necessary for the Tumor's Growth

All nascent neoplasms probably elicit at least a weak immune reaction. However, the initial effect of the weak immune reaction on a nascent tumor is always stimulatory rather than inhibitory to tumor growth, assuming only that exposure to the tumor antigens did not antedate the initiation of the neoplasm (as may occur in some virally induced tumors). This conclusion derives from the observation that the relationship between the magnitude of an adaptive immune reaction and tumor growth is not linear but varies such that while large quantities of antitumor immune reactants tend to inhibit tumor growth, smaller quantities of the same reactants are, for unknown reasons, stimulatory. Any immune reaction must presumably be small before it can become large; hence the initial reaction to the first presentation of a tumor antigen must always be small and in the stimulatory portion of this nonlinear relationship. In mouse-skin carcinogenesis experiments it was found that premalignant papillomas were variously immunogenic, but that the carcinomas that arose in them were, presumably because of induced immune tolerance, nonimmunogenic in the animal of origin

Evaluating the use of user content feed swapping for counteracting filter bubbles

Abstract. The term filter bubble refers to a phenomenon in which a recommendation system fails to offer diverse or novel content, and instead offers content that reinforces particular belief systems. Filter bubbles are considered harmful when they restrict users’ exposure to diverse content and thereby reinforce potentially harmful or misinformed ideologies, contribute to the spread of misinformation, and foster the creation of echo chambers. This thesis proposes a solution to counteract the effects of filter bubbles by providing users with the option to switch content feeds with their least similar users’ feed. The solution was achieved by substituting the correlation coefficient used in collaborative filtering recommendation systems. An application was developed to simulate post recommendations for users, initially employing a traditional collaborative filtering system. This was then followed by a collaborative filtering system that recommended posts based on the likes of the least similar user to the current user. User engagement metrics and cognitive mapping metrics were used to evaluate this solution. If the solution did not negatively affect user engagement and demonstrated an ability to increase the diversity of users’ bias perception and promote a more nuanced understanding of bias within the social media application, it met the requirements of these metrics. There was an overall increase in user engagement after the users’ feed was swapped. Moreover, the users’ perception of bias became more diversified, indicating that the solution prompted a broader awareness of bias within the social media application users were engaging with. Based on these results, the proposed solution was deemed as potentially effective in addressing the filter bubble problem. The solution’s viability was established solely within a simulated environment. To determine its real-world applicability, it requires further testing in a naturalistic environment with more participants

Seasonal Occurrence of the Sod Webworm Moths (Lepidoptera: Crambidae) of Ohio

While nearly 100 species of sod webworms are known to occur in North America, the species complex and seasonal occurrence of these moths has been documented in relatively few states. For Ohio, there is little published record of the sod webworm species complex, and the seasonal occurrence of only a few economically important species has been documented. Using black light traps, sod web worm adult flight activity was monitored over the course of three to five years at four different locations throughout Ohio. In this paper we report the seasonal occurrence of sod web worms species captured at these locations. These data provide a historical benchmark of sod web­worm species diversity, local abundance, and seasonal occurrence in Ohio

A new kink in an old theory of carcinogenesis

According to Berenblum’s two-stage hypothesis, the first stage in carcinogenesis is the production of benign premalignant lesions. Between this initiation stage and the formation of a malignant tumor there is often a long lag phase. We propose that this lag is caused by the delay in the formation of a new and rare tumor-specific antigen, which induces an immune response that stimulates tumor growth. Such tumor-specific antigens could arise as a result of a mutator-like phenotype, which is supposedly present in the benign initial stage of carcinogenesis. According to this hypothesis, the first stage lesion provides a weakly mutagenic environment conducive to the formation of the new antigen(s). If no such new antigens appear so there is no consequent immune response, it is argued that carcinogenesis would seldom if ever ensue