740 research outputs found

    Improving Abstraction in Text Summarization

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    Abstractive text summarization aims to shorten long text documents into a human readable form that contains the most important facts from the original document. However, the level of actual abstraction as measured by novel phrases that do not appear in the source document remains low in existing approaches. We propose two techniques to improve the level of abstraction of generated summaries. First, we decompose the decoder into a contextual network that retrieves relevant parts of the source document, and a pretrained language model that incorporates prior knowledge about language generation. Second, we propose a novelty metric that is optimized directly through policy learning to encourage the generation of novel phrases. Our model achieves results comparable to state-of-the-art models, as determined by ROUGE scores and human evaluations, while achieving a significantly higher level of abstraction as measured by n-gram overlap with the source document

    Salinity effects in an oceanic mixed-layer model.

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    http://archive.org/details/salinityeffectsi00pau

    Hydration effects turn a highly stretched polymer from an entropic into an energetic spring

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    Polyethylene glycol (PEG) is a structurally simple and nontoxic water-soluble polymer that is widely used in medical and pharmaceutical applications as molecular linker and spacer. In such applications, PEG’s elastic response against conformational deformations is key to its function. According to text-book knowledge, a polymer reacts to the stretching of its end-to-end separation by a decrease in entropy that is due to the reduction of available conformations, which is why polymers are commonly called entropic springs. By a combination of single-molecule force spectroscopy experiments with molecular dynamics simulations in explicit water, we show that entropic hydration effects almost exactly compensate the chain conformational entropy loss at high stretching. Our simulations reveal that this entropic compensation is due to the stretching-induced release of water molecules that in the relaxed state form double hydrogen bonds with PEG. As a consequence, the stretching response of PEG is predominantly of energetic, not of entropic, origin at high forces and caused by hydration effects, while PEG backbone deformations only play a minor role. These findings demonstrate the importance of hydration for the mechanics of macromolecules and constitute a case example that sheds light on the antagonistic interplay of conformational and hydration degrees of freedom

    ANALISIS PENDAPATAN USAHATANI PADI SAWAH (Oryza sativa L) DI DESA KAUDITAN 1 KECAMATAN KAUDITAN KABUPATEN MINAHASA UTARA

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    This research aims to analyzed income of rice paddy farmers. This research conducted in Kauditan 1 village north Minahasa Regency from june to july 2018. The method used survey method by visiting rice paddy farming. Data collection method in this research using primary data. Primay data obtained from interview with rice paddy farmers using questionnaires, and secondary data from related agency statistic center bureau north Minahasa Regency. The sampling all rice paddy farmers, 5 respondent. Variable in this research is characteristic of farming: land area, land tenure status, seeds, fertilizers, medicine and characteristic of farmer: age, education level, family member, fixed cost, variable cost, total cost, price, production quantity. Data presented in the table form and analyzed descriptively. The result showed that average income of rice paddy farmers Rp.31,849,420 and average income based on land area Rp.18,780,342 with R/C ratio more than 1,2.47.*lwths*

    Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation

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    Glutaminyl-tRNA synthetase from Deinococcus radiodurans possesses a C-terminal extension of 215 residues appending the anticodon-binding domain. This domain constitutes a paralog of the Yqey protein present in various organisms and part of it is present in the C-terminal end of the GatB subunit of GatCAB, a partner of the indirect pathway of Gln-tRNA(Gln) formation. To analyze the peculiarities of the structure–function relationship of this GlnRS related to the Yqey domain, a structure of the protein was solved from crystals diffracting at 2.3 Å and a docking model of the synthetase complexed to tRNA(Gln) constructed. The comparison of the modeled complex with the structure of the E. coli complex reveals that all residues of E. coli GlnRS contacting tRNA(Gln) are conserved in D. radiodurans GlnRS, leaving the functional role of the Yqey domain puzzling. Kinetic investigations and tRNA-binding experiments of full length and Yqey-truncated GlnRSs reveal that the Yqey domain is involved in tRNA(Gln) recognition. They demonstrate that Yqey plays the role of an affinity-enhancer of GlnRS for tRNA(Gln) acting only in cis. However, the presence of Yqey in free state in organisms lacking GlnRS, suggests that this domain may exert additional cellular functions

    Behavioral Health and Performance (BHP) Standing Review Panel (SRP) Final Report

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    The first meeting of the Behavioral Health and Performance (BHP) Standing Review Panel (SRP) was held in Houston, TX on November 1-3, 2009. Our task was to assess the Integrated Research Plan (IRP) related to the fields covered in the SRP charge (see section VIII). Having considered and discussed the extensive materials distributed prior to the meeting, and the highly informative briefings by the NASA BHP Human Research Program (HRP) personnel during the site visit, the SRP agreed that the IRP is comprehensive and was developed carefully. Question and answer periods with the presenters were particularly productive and helpful to the SRP. The presenters' willingness to share information and positive responses to the SRP's suggestions were greatly appreciated. Although the IRP and related documents are impressive, the SRP does have a number of recommendations regarding both the overall plan and its component parts

    Evaluation of Total Daily Dose and Glycemic Control for Patients Taking U-500 Regular Insulin Admitted to the Hospital

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    OBJECTIVE: Patients using U-500 regular insulin are severely insulin resistant, requiring high doses of insulin. It has been observed that a patient\u27s insulin requirements may dramatically decrease during hospitalization. This study sought to systematically investigate this phenomenon. METHODS: We performed a retrospective chart review of patients with U-500 insulin outpatient regimens who were admitted to the San Antonio Military Medical Center over a 5-year period. Each patient\u27s outpatient total daily dose (TDD) of insulin was compared to the average inpatient TDD. The outpatient estimated average glucose (eAG) was calculated from the glycated hemoglobin (HbA1c) and compared to the average inpatient glucose. RESULTS: There were 27 patients with a total of 62 separate admissions. The average age was 64.4 years, with a mean body mass index of 38.9 kg/m CONCLUSION: U-500 insulin is prone to errors in the hospital setting, so conversion to U-100 insulin is a preferred option. Despite a significant reduction in insulin TDD, these patients had clinically similar glucose levels. Therefore, patients taking U-500 insulin as an outpatient can be converted to a U-100 basal-bolus regimen with at least a 50% reduction of their outpatient TDD. ABBREVIATIONS: BG = blood glucose eAG = estimated average glucose HbA1c = glycated hemoglobin NPO = nil per os SPSS = Statistical Package for the Social Sciences TDD = total daily dose
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