Sequences for b-tubulin 2

Sequences submitted to Genbank for beta-tubulin

Genotypes

Genotype over all loci for each sampled individual

Sequences for cox1-trnM IGR

DNA Sequences submitted to Genbank for cox1-trnM intergenic regio

Sequences for b-tubulin 2

Sequences submitted to Genbank for beta-tubulin

Haplotype Frequencies per population

Haplotype frequencies per locus for each population. Loci studied: beta-tubulin 1, beta-tubulin 2 and cox1-trnM IGR. Populations: Belize, Panama, Puerto Rico, Bermuda, Abrolhos (Brazil), Joao Pessoa (Brazil), Fortaleza (Brazil), Sao Tome

Ichthyolith Counts for DSDP Site 596 and ODP Site 886

IODP Sample identifiers, downcore depth, age, ichthyolith counts and ichthyolith accumulation rates for DSDP Site 596 and ODP Site 886

The VISA-A (sedentary) should be used for sedentary patients with Achilles tendinopathy: a modified version of the VISA-A developed and evaluated in accordance with the COSMIN checklist

Objective To develop and evaluate a modified version of the Victorian Institute of Sport Assessment-Achilles (VISA-A) questionnaire, for use in sedentary patients with Achilles tendinopathy, using the Consensus-based Standards for the selection of health Measurement Instruments recommendations. Methods Twenty-two sedentary patients with Achilles tendinopathy completed the VISA-A and provided feedback regarding the relevance, comprehensiveness and comprehensibility of each item, response options and instructions. Patient and professional feedback was used to develop the VISA-A (sedentary) questionnaire. Reliability, validity and responsiveness of the VISA-A (sedentary) was evaluated in 51 sedentary patients with Achilles tendinopathy: 47.1% women, mean age 64.8 (SD 11.24). Results Factor analysis identified two dimensions (symptoms and activity) for the VISA-A (sedentary). Test–retest reliability was excellent for symptoms (intraclass correlation coefficient, ICC=0.991) and activity (ICC=0.999). Repeatability was 1.647 for symptoms and 0.549 for activity. There was a significant difference between the VISA-A and VISA-A (sedentary) scores both pretreatment and post-treatment. There was stronger correlation between the pretreatment to post-treatment change in the VISA-A (sedentary) scores (r=0.420 for symptoms, r=0.407 for activity) and the global rating of change than the VISA-A scores (r=0.253 for symptoms, r=0.186 for activity). Conclusion The VISA-A (sedentary) demonstrates adequate reliability, validity and responsiveness in sedentary patients with Achilles tendinopathy. The VISA-A (sedentary) is a more appropriate measure than the VISA-A for this cohort and is recommended for clinical and research purposes.</p