54 research outputs found

    Service Learning and Democratic Citizenship

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    Over the course of this semester I have become a citizen of New Brunswick. It could be argued that I was a citizen here well before registering for the course, but I did not feel as if I were one. Having taken the course, I now know why I must work for change, and never accept the status quo - things can always be better. I am now aware of what is happening around me. New Brunswick extends beyond the [campus] bus route. It is filled with people who need aid, people who give aid. people who cannot be bothered to give aid, and people who, like me, don\u27t realize they are citizens at all

    Service Learning, Diversity, and the Liberal Arts Curriculum

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    In the many years I have been teaching, I have attempted to engage students in issues surrounding their place as citizens in a multicultural democracy. In my second year of involvement in AAC&U\u27s American Commitments: Diversity, Democracy, and Liberal Learning project, I have become acquainted with the perspectives of faculty from different disciplines and institutions and with a wide array of excellent multicultural materials and curricula; but even the best of curricula tend to be somewhat abstract

    Critical Reflection

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    In this workshop, we wanted to convey the importance of tying critical reflection activities to the learning objectives of the service experience and/or course. We started by asking participants to define critical reflection and then to list some common learning objectives associated with service-learning courses and co-curricular service. Finally, participants described many of the activities they use with their participants and students. The result is a thorough list of activities that service-learning practitioners find effective in achieving their course objectives

    A. Season of Service: Introducing Service Learning into the Liberal Arts Curriculum

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    We live in times when rights and obligations have become uncoupled. Individuals regard themselves almost exclusively as private persons with responsibilities only to family and job and yet possessing endless rights against a distant and alien state in relationship to which they think or themselves, at best, as watchdogs and clients and, at worst, as adversaries and victims. The idea of service to country or to the institutions by which rights and liberty are legitimized and sustained has fairly vanished

    Acting Locally in a Flat World: Global Citizenship and the Democratic Practice of Service-Learning

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    This paper series seems especially significant this year, as Campus Compact celebrates an important milestone. The context has certainly changed over the decades since the founding of Campus Compact twenty years ago. For while Campus Compact has grown impressively to more than 950 member campuses with 31 state offices under the leadership of Elizabeth Hollander, there is also a sense that service-learning is at a crossroads. At least one dimension for educators to consider is the connection between the local and the global, and the importance of global citizenship and democratic practices which promote global citizenship. To be engaged and relevant requires that service-learning includes a large vision, along with democratic practices for acting locally with global intentions. The flattened world which Thomas Friedman has popularly termed for the rapid rise of globalization since the start of the 21st century has important implications for service-learning educators trying to implement John Dewey\u27s vision of building democratic, neighborly communities. It requires us to ask: if democracy begins at home, what does this mean in the context of an increasingly global society

    Higher Education Exchange: 2014

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    This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share.The Higher Education Exchange is founded on a thought articulated by Thomas Jefferson in 1820: "I know no safe depository of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."In the tradition of Jefferson, the Higher Education Exchange agrees that a central goal of higher education is to help make democracy possible by preparing citizens for public life. The Higher Education Exchange is part of a movement to strengthen higher education's democratic mission and foster a more democratic culture throughout American society.Working in this tradition, the Higher Education Exchange publishes interviews, case studies, analyses, news, and ideas about efforts within higher education to develop more democratic societies

    Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano.

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    The free-living flatworm, Macrostomum lignano has an impressive regenerative capacity. Following injury, it can regenerate almost an entirely new organism because of the presence of an abundant somatic stem cell population, the neoblasts. This set of unique properties makes many flatworms attractive organisms for studying the evolution of pathways involved in tissue self-renewal, cell-fate specification, and regeneration. The use of these organisms as models, however, is hampered by the lack of a well-assembled and annotated genome sequences, fundamental to modern genetic and molecular studies. Here we report the genomic sequence of M. lignano and an accompanying characterization of its transcriptome. The genome structure of M. lignano is remarkably complex, with ∼75% of its sequence being comprised of simple repeats and transposon sequences. This has made high-quality assembly from Illumina reads alone impossible (N50=222 bp). We therefore generated 130× coverage by long sequencing reads from the Pacific Biosciences platform to create a substantially improved assembly with an N50 of 64 Kbp. We complemented the reference genome with an assembled and annotated transcriptome, and used both of these datasets in combination to probe gene-expression patterns during regeneration, examining pathways important to stem cell function.This work is supported by National Institutes of Health Grants R37 GM062534 (to G.J.H.) and R01-HG006677 (to M.S.); National Science Foundation Grant DBI-1350041 (to M.S.); and a Swiss National Science Foundation Grant 31003A-143732 (to L.S.). This work was performed with assistance from Cold Spring Harbor Laboratory Shared Resources, which are funded, in part, by Cancer Center Support Grant 5P30CA045508.This is the final version of the article. It first appeared from PNAS via http://dx.doi.org/10.1073/pnas.151671811

    Online proton therapy monitoring: Clinical test of a Silicon-photodetector-based in-beam PET

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    Particle therapy exploits the energy deposition pattern of hadron beams. The narrow Bragg Peak at the end of range is a major advantage but range uncertainties can cause severe damage and require online verification to maximise the effectiveness in clinics. In-beam Positron Emission Tomography (PET) is a non-invasive, promising in-vivo technique, which consists in the measurement of the β+ activity induced by beam-tissue interactions during treatment, and presents the highest correlation of the measured activity distribution with the deposited dose, since it is not much influenced by biological washout. Here we report the first clinical results obtained with a state-of-the-art in-beam PET scanner, with on-the-fly reconstruction of the activity distribution during irradiation. An automated time-resolved quantitative analysis was tested on a lacrimal gland carcinoma case, monitored during two consecutive treatment sessions. The 3D activity map was reconstructed every 10 s, with an average delay between beam delivery and image availability of about 6 s. The correlation coefficient of 3D activity maps for the two sessions (above 0.9 after 120 s) and the range agreement (within 1 mm) prove the suitability of in-beam PET for online range verification during treatment, a crucial step towards adaptive strategies in particle therapy

    Search for Nucleon Decays induced by GUT Magnetic Monopoles with the MACRO Experiment

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    The interaction of a Grand Unification Magnetic Monopole with a nucleon can lead to a barion-number violating process in which the nucleon decays into a lepton and one or more mesons (catalysis of nucleon decay). In this paper we report an experimental study of the effects of a catalysis process in the MACRO detector. Using a dedicated analysis we obtain new magnetic monopole (MM) flux upper limits at the level of 31016cm2s1sr1\sim 3\cdot 10^{-16} cm^{-2} s^{-1} sr^{-1} for 1.1104β51031.1\cdot 10^{-4} \le |\beta| \le 5\cdot 10^{-3}, based on the search for catalysis events in the MACRO data. We also analyze the dependence of the MM flux limit on the catalysis cross section.Comment: 12 pages, Latex, 10 figures and 2 Table

    Localization of anatomical changes in patients during proton therapy with in-beam PET monitoring: a voxel-based morphometry approach exploiting Monte Carlo simulations

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    Purpose: In-beam positron emission tomography (PET) is one of the modalities that can be used for in vivo noninvasive treatment monitoring in proton therapy. Although PET monitoring has been frequently applied for this purpose, there is still no straightforward method to translate the information obtained from the PET images into easy-to-interpret information for clinical personnel. The purpose of this work is to propose a statistical method for analyzing in-beam PET monitoring images that can be used to locate, quantify, and visualize regions with possible morphological changes occurring over the course of treatment. Methods: We selected a patient treated for squamous cell carcinoma (SCC) with proton therapy, to perform multiple Monte Carlo (MC) simulations of the expected PET signal at the start of treatment, and to study how the PET signal may change along the treatment course due to morphological changes. We performed voxel-wise two-tailed statistical tests of the simulated PET images, resembling the voxel-based morphometry (VBM) method commonly used in neuroimaging data analysis, to locate regions with significant morphological changes and to quantify the change. Results: The VBM resembling method has been successfully applied to the simulated in-beam PET images, despite the fact that such images suffer from image artifacts and limited statistics. Three dimensional probability maps were obtained, that allowed to identify interfractional morphological changes and to visualize them superimposed on the computed tomography (CT) scan. In particular, the characteristic color patterns resulting from the two-tailed statistical tests lend themselves to trigger alarms in case of morphological changes along the course of treatment. Conclusions: The statistical method presented in this work is a promising method to apply to PET monitoring data to reveal interfractional morphological changes in patients, occurring over the course of treatment. Based on simulated in-beam PET treatment monitoring images, we showed that with our method it was possible to correctly identify the regions that changed. Moreover we could quantify the changes, and visualize them superimposed on the CT scan. The proposed method can possibly help clinical personnel in the replanning procedure in adaptive proton therapy treatments
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