550 research outputs found
Restaurant Revenue Management: Applying Yield Management to the Restaurant Industry
The crucial element in a strategy for boosting restaurant revenues may be to relate prices to the length of time guests spend at the table. But, as the Witch of the West told Dorothy, the issue is how to do it
Temporal trends in the discovery of human viruses
On average, more than two new species of human virus are reported every year. We constructed the cumulative species discovery curve for human viruses going back to 1901. We fitted a statistical model to these data; the shape of the curve strongly suggests that the process of virus discovery is far from complete. We generated a 95% credible interval for the pool of as yet undiscovered virus species of 38–562. We extrapolated the curve and generated an estimate of 10–40 new species to be discovered by 2020. Although we cannot predict the level of health threat that these new viruses will present, we conclude that novel virus species must be anticipated in public health planning. More systematic virus discovery programmes, covering both humans and potential animal reservoirs of human viruses, should be considered
North Dakota Economic-Demographic Assessment Model (NEDAM): Technical Description
This report describes the logic, structure, data bases, and operational procedures of the North Dakota model.Research Methods/ Statistical Methods,
Applying phylogenomics to understand the emergence of Shiga Toxin producing Escherichia coli O157:H7 strains causing severe human disease in the United Kingdom
Shiga Toxin producing Escherichia coli (STEC) O157:H7 is a recently emerged zoonotic pathogen with considerable morbidity. Since the serotype emerged in the 1980s, research has focussed on unravelling the evolutionary events from the E. coli O55:H7 ancestor to the contemporaneous globally dispersed strains. In this study the genomes of over 1000 isolates from human clinical cases and cattle, spanning the history of STEC O157:H7 in the United Kingdom were sequenced. Phylogenetic analysis reveals the ancestry, key acquisition events and global context of the strains. Dated phylogenies estimate the time to the most recent common ancestor of the current circulating global clone to 175 years ago, followed by rapid diversification. We show the acquisition of specific virulence determinates occurred relatively recently and coincides with its recent detection in the human population. Using clinical outcome data from 493 cases of STEC O157:H7 we assess the relative risk of severe disease including HUS from each of the defined clades in the population and show the dramatic effect Shiga toxin complement has on virulence. We describe two strain replacement events that have occurred in the cattle population in the UK over the last 30 years; one resulting in a highly virulent strain that has accounted for the majority of clinical cases in the UK over the last decade. This work highlights the need to understand the selection pressures maintaining Shiga-toxin encoding bacteriophages in the ruminant reservoir and the study affirms the requirement for close surveillance of this pathogen in both ruminant and human populations
Anointed or appointed? Father–daughter succession within the family business
With the focus on events and outcomes shaping most of the existing family business research
on intra-family succession, the subtleties of the incumbent-successor relationship and the
dynamic nature of succession as a process of becoming is somewhat neglected. In particular,
we have limited understanding of how successor identities are constructed as legitimate
between incumbent and successor during father-daughter succession. This article addresses this
gap in understanding by exploring how the daughter successor engages in identity work with
the father incumbent during the process of succession and the role of father-daughter gendered
relations in shaping her successor identity. Using a two-stage research design strategy, we draw
upon empirical evidence derived from 14 individual and joint semi-structured interviews to
present a narrative analysis of five father-daughter dyads. In so doing, we unveil how the
daughter’s successor identity was co-constructed as legitimate and how father-daughter
gendered relations influenced this process. Although daughters rely on certain father-daughter
relations (preparation, endorsement and osmotic credibility) for legitimacy, they also need to
develop independently from their father in order to heighten their own visibility and establish
credibility
Ursinus College Alumni Journal, November 1961
The president\u27s wife writes • Mater Ursini • The Ursinus College European tour • Admiral Moreell looks at a philosopher • Zucker looks at Moreell • A woman\u27s approach to peace • Founders\u27 Day • 1962 Forum programs • Cutting campus • From Alaska to Greenland • Faith and freedom in Taiwan • Reginald Helfferich honored • Poet King • Henry P. Laughlin, \u2738 • Robert Pease, \u2733 • Ursinus student at White House conference • Harleston R. Wood • Football • Soccer • Hockey • Basketball • Wrestling • 53.5% contribute to Loyalty Fund in 1961 • Progress report 1962 campaign • 1961 campaign results • The Century Club • Loyalty Fund all-stars • Loyalty Fund kick-off dinner • Matching gifts • Results of the 1961 Loyalty Fund campaign • Contributors to the 1961 Loyalty Fund campaign • Class notes • Weddings • Births • Necrology • Sing along with us • New faculty membershttps://digitalcommons.ursinus.edu/alumnijournal/1072/thumbnail.jp
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How predation and landscape fragmentation affect vole population dynamics
Background: Microtine species in Fennoscandia display a distinct north-south gradient from regular cycles to stable
populations. The gradient has often been attributed to changes in the interactions between microtines and their predators.
Although the spatial structure of the environment is known to influence predator-prey dynamics of a wide range of species,
it has scarcely been considered in relation to the Fennoscandian gradient. Furthermore, the length of microtine breeding
season also displays a north-south gradient. However, little consideration has been given to its role in shaping or generating
population cycles. Because these factors covary along the gradient it is difficult to distinguish their effects experimentally in
the field. The distinction is here attempted using realistic agent-based modelling.
Methodology/Principal Findings: By using a spatially explicit computer simulation model based on behavioural and
ecological data from the field vole (Microtus agrestis), we generated a number of repeated time series of vole densities
whose mean population size and amplitude were measured. Subsequently, these time series were subjected to statistical
autoregressive modelling, to investigate the effects on vole population dynamics of making predators more specialised, of
altering the breeding season, and increasing the level of habitat fragmentation. We found that fragmentation as well as the
presence of specialist predators are necessary for the occurrence of population cycles. Habitat fragmentation and predator
assembly jointly determined cycle length and amplitude. Length of vole breeding season had little impact on the
oscillations.
Significance: There is good agreement between our results and the experimental work from Fennoscandia, but our results
allow distinction of causation that is hard to unravel in field experiments. We hope our results will help understand the
reasons for cycle gradients observed in other areas. Our results clearly demonstrate the importance of landscape
fragmentation for population cycling and we recommend that the degree of fragmentation be more fully considered in
future analyses of vole dynamics
Robust Inference of Monocot Deep Phylogeny Using an Expanded Multigene Plastid Data Set
We use multiple photosynthetic, chlororespiratory, and plastid translation apparatus loci and their associated noncoding regions (ca. 16 kb per taxon, prior to alignment) to make strongly supported inferences of the deep internal branches of monocot phylogeny. Most monocot relationships are robust (an average of ca. 91 % bootstrap support per branch examined), including those poorly supported or unresolved in other studies. Our data strongly support a sister-group relationship between Asparagales and the commelinid monocots, the inclusion of the orchids in Asparagales, and the status of Petrosaviaceae as the sister group of all monocots except Acorus and Alismatales. The latter finding supports recognition of the order Petrosaviales. Also strongly supported is a placement of Petermannia disjunct from Colchicaceae (Liliales) and a sister-group relationship between Commelinales and Zingiberales. We highlight the remaining weak areas of monocot phylogeny, including the positions of Dioscoreales, Liliales, and Pandanales. Despite substantial variation in the overall rate of molecular evolution among lineages, inferred amounts of change among codon-position data partitions are correlated with each other across the monocot tree, consistent with low incongruence between these partitions. Ceratophyllum and Chloranthaceae appear to have a destabilizing effect on the position of the monocots among other angiosperms; the issue of monocot placement in broader angiosperm phylogeny remains problematic
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BioTIME: A database of biodiversity time series for the Anthropocene.
MotivationThe BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community-led open-source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal patterns of biodiversity in the Anthropocene.Main types of variables includedThe database contains 8,777,413 species abundance records, from assemblages consistently sampled for a minimum of 2 years, which need not necessarily be consecutive. In addition, the database contains metadata relating to sampling methodology and contextual information about each record.Spatial location and grainBioTIME is a global database of 547,161 unique sampling locations spanning the marine, freshwater and terrestrial realms. Grain size varies across datasets from 0.0000000158 km2 (158 cm2) to 100 km2 (1,000,000,000,000 cm2).Time period and grainBioTIME records span from 1874 to 2016. The minimal temporal grain across all datasets in BioTIME is a year.Major taxa and level of measurementBioTIME includes data from 44,440 species across the plant and animal kingdoms, ranging from plants, plankton and terrestrial invertebrates to small and large vertebrates.Software format.csv and .SQL
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