External bioelectrodes - A battery substitute for biological telemetry systems Final report, period ending 28 Feb. 1966

Electrode pair power output in saline and on skin for determination of telemetry system power source material

WHAM Observations of H-Alpha, [S II], and [N II] toward the Orion and Perseus Arms: Probing the Physical Conditions of the Warm Ionized Medium

A large portion of the Galaxy (l = 123 deg to 164 deg, b = -6 deg to -35 deg), which samples regions of the Local (Orion) spiral arm and the more distant Perseus arm, has been mapped with the Wisconsin H-Alpha Mapper (WHAM) in the H-Alpha, [S II] 6716, and [N II] 6583 lines. Several trends noticed in emission-line investigations of diffuse gas in other galaxies are confirmed in the Milky Way and extended to much fainter emission. We find that the [S II]/H-Alpha and [N II]/H-Alpha ratios increase as absolute H-Alpha intensities decrease. For the more distant Perseus arm emission, the increase in these ratios is a strong function of Galactic latitude and thus, of height above the Galactic plane. The [S II]/[N II] ratio is relatively independent of H-Alpha intensity. Scatter in this ratio appears to be physically significant, and maps of it suggest regions with similar ratios are spatially correlated. The Perseus arm [S II]/[N II] ratio is systematically lower than Local emission by 10%-20%. With [S II]/[N II] fairly constant over a large range of H-Alpha intensities, the increase of [S II]/H-Alpha and [N II]/H-Alpha with |z| seems to reflect an increase in temperature. Such an interpretation allows us to estimate the temperature and ionization conditions in our large sample of observations. We find that WIM temperatures range from 6,000 K to 9,000 K with temperature increasing from bright to faint H-Alpha emission (low to high [S II]/H-Alpha and [N II]/H-Alpha) respectively. Changes in [S II]/[N II] appear to reflect changes in the local ionization conditions (e.g. the S+/S++ ratio). We also measure the electron scale height in the Perseus arm to be 1.0+/-0.1 kpc, confirming earlier, less accurate determinations.Comment: 28 pages, 10 figures. Figures 2 and 3 are full color--GIFs provided here, original PS figures at link below. Accepted for publication in ApJ. More information about the WHAM project can be found at http://www.astro.wisc.edu/wham/ . REVISION: Figure 6, bottom panel now contains the proper points. No other changes have been mad

Dynamic behavior of an unsteady trubulent boundary layer

Experiments on an unsteady turbulent boundary layer are reported in which the upstream portion of the flow is steady (in the mean) and in the downstream region, the boundary layer sees a linearly decreasing free stream velocity. This velocity gradient oscillates in time, at frequencies ranging from zero to approximately the bursting frequency. For the small amplitude, the mean velocity and mean turbulence intensity profiles are unaffected by the oscillations. The amplitude of the periodic velocity component, although as much as 70% greater than that in the free stream for very low frequencies, becomes equal to that in the free stream at higher frequencies. At high frequencies, both the boundary layer thickness and the Reynolds stress distribution across the boundary layer become frozen. The behavior at higher amplitude is quite similar. At sufficiently high frequencies, the boundary layer thickness remains frozen at the mean value over the oscillation cycle, even though flow reverses near the wall during a part of the cycle

NuSTAR Observations of G11.2–0.3

We present in this paper the hard X-ray view of the pulsar wind nebula in G11.2−0.3 and its central pulsar powered pulsar J1811−1925 as seen by NuSTAR. We complement the data with Chandra for a more complete picture and confirm the existence of a hard, power-law component in the shell with photon index Γ = 2.1 ± 0.1, which we attribute to synchrotron emission. Our imaging observations of the shell show a slightly smaller radius at higher energies, consistent with Chandra results, and we find shrinkage as a function of increased energy along the jet direction, indicating that the electron outflow in the PWN may be simpler than that seen in other young PWNe. Combining NuSTAR with INTEGRAL, we find that the pulsar spectrum can be fit by a power law with Γ = 1.32 ± 0.07 up to 300 keV without evidence of curvature

Accretional heating of the satellites of Saturn and Uranus

Voyager images of the satellites of Saturn and Uranus have shown that these bodies are characterized by remarkable diversity and surprisingly complex geologic histories. Despite their small sizes, a number of the satellites show unambiguous evidence for resurfacing. The goal was to develop a detailed model for heating of these small satellites, and then to explore the consequences of variations in the free parameters in the model. Specifically an attempt was made to determine for what range of conditions melting will occur in these satellites. Along with varying a number of model parameters, the important effects of inclusion of small amounts of ammonia and methane in the system were considered

On the lack of X-ray iron line reverberation in MCG-6-30-15: Implications for the black hole mass and accretion disk structure

We use the method of Press, Rybicki & Hewitt (1992) to search for time lags and time leads between different energy bands of the RXTE data for MCG-6-30-15. We tailor our search in order to probe any reverberation signatures of the fluorescent iron Kalpha line that is thought to arise from the inner regions of the black hole accretion disk. In essence, an optimal reconstruction algorithm is applied to the continuum band (2-4keV) light curve which smoothes out noise and interpolates across the data gaps. The reconstructed continuum band light curve can then be folded through trial transfer functions in an attempt to find lags or leads between the continuum band and the iron line band (5-7keV). We find reduced fractional variability in the line band. The spectral analysis of Lee et al. (1999) reveals this to be due to a combination of an apparently constant iron line flux (at least on timescales of few x 10^4s), and flux correlated changes in the photon index. We also find no evidence for iron line reverberation and exclude reverberation delays in the range 0.5-50ksec. This extends the conclusions of Lee et al. and suggests that the iron line flux remains constant on timescales as short as 0.5ksec. The large black hole mass (>10^8Msun) naively suggested by the constancy of the iron line flux is rejected on other grounds. We suggest that the black hole in MCG-6-30-15 has a mass of M_BH~10^6-10^7Msun and that changes in the ionization state of the disk may produce the puzzling spectral variability. Finally, it is found that the 8-15keV band lags the 2-4keV band by 50-100s. This result is used to place constraints on the size and geometry of the Comptonizing medium responsible for the hard X-ray power-law in this AGN.Comment: 11 pages, 13 postscript figures. Accepted for publication in Ap

Comparison of osteoporosis pharmacotherapy fracture rates: Analysis of a marketScan® claims database cohort

Background: Several different classes of medications have been shown to be efficacious at preventing fractures in patients with osteoporosis. No study has compared real world efficacy at preventing fractures between all currently approved medications. Objectives: To directly compare the efficacy of all currently available osteoporosis medications by using a large population claims database. Methods: The Truven Health Analytics MarketScan® database from 2008 - 2012 was used to identify all patients who started a new osteoporosis medication. Patients who experienced a fracture after at least 12 months of treatment were identified and risk factors for fracture for all patients were recorded. Logistic regression was used to account for and quantify the contribution of risk factors, and to make direct comparisons between different osteoporosis medications. Results: A total of 51649 patients were included in the cohort, with an average age of 56 years. The overall incidence rate of fracture was 1.55 per 100 person - years of treatment. Orally administered medications had the lowest fracture rates, led by raloxifene and alendronate (1.24 and 1.54 respectively), while parenterally administered medications including teriparatide and zolerdonic acid had the highest rates (3.90 and 1.98 respectively). No statistically significant differences found between oral or parenterally administered bisphosphonate medications. Conclusions: While patients taking orally administered drugs including bisphosphonates had less frequent incident fracture no statistically significant differences were found between most drugs in head - to - head comparisons, even considering the route of administration of bisphosphonates. These findings support previous evidence that minimal differences in efficacy exist between different osteoporosis medications. This is the first study using a large database to compare all currently available osteoporosis treatments and will hopefully be augmented by further study to provide more evidence to make clinical decisions on osteoporosis medication use. © 2017 American Association of Neuropathologists, Inc

Therapeutic outcomes in a museum? “You don't get them by aiming for them”. How a focus on arts participation promotes inclusion and well-being

Background: The three year “Ways of Seeing” project was hosted by an award-winning museum and included adults with long-term diagnoses associated with mental health and physical impairments. The participants were involved throughout the project, preparing and curating artwork for a major public exhibition. Methods: Qualitative data were collected to explore meanings of the project from the perspective of participants, the project manager and the public, using interviews, participant observation and comment cards. Results: The project was successful in engaging the participants who had previously often felt excluded from mainstream art spaces. Findings about the benefits of arts participation echoed other studies but participants highlighted some difficulty with the ending of the project. Public perceptions were positive, acclaiming the thought-provoking quality of the exhibition. Interviews and participant observation revealed the importance of egalitarian leadership, mutual trust and the absence of any therapeutic agenda. Conclusion: Developing similar projects would offer opportunities to foster diverse artistic communities and empower people with experiences of disability and mental health conditions

Sinking properties of some phytoplankton shapes and the relation of form resistance to morphological diversity of plankton – an experimental study

Form resistance (Phi) is a dimensionless number expressing how much slower or faster a particle of any form sinks in a fluid medium than the sphere of equivalent volume. Form resistance factors of PVC models of phytoplankton sinking in glycerin were measured in a large aquarium (0.6 x 0.6 x 0.95 m). For cylindrical forms, a positive relationship was found between Phi and length/ width ratio. Coiling decreased Phi in filamentous forms. Form resistance of Asterionella colonies increased from single cells up to 6-celled colonies than remained nearly constant. For Fragilaria crotonensis chains, no such upper limit to Phi was observed in chains of up to 20 cells ( longer ones were not measured). The effect of symmetry on Phi was tested in 1 - 6-celled Asterionella colonies, having variable angles between the cells, and in Tetrastrum staurogeniaeforme coenobia, having different spine arrangements. In all cases, symmetric forms had considerably higher form resistance than asymmetric ones. However, for Pediastrum coenobia with symmetric/asymmetric fenestration, no difference was observed with respect to symmetry. Increasing number and length of spines on Tetrastrum coenobia substantially increased Phi. For a series of Staurastrum forms, a significant positive correlation was found between arm-length/cell-width ratio and Phi: protuberances increased form resistance. Flagellates (Rhodomonas, Gymnodinium) had a Phi 1. The highest value ( Phi = 8.1) was established for a 20-celled Fragilaria crotonensis chain. Possible origin of the so-called 'vital component' ( a factor that shows how much slower viable populations sink than morphologically similar senescent or dead ones) is discussed, as is the role of form resistance in evolution of high diversity of plankton morphologies

Aircraft cabin water spray disbenefits study

The concept of utilizing a cabin water spray system (CWSS) as a means of increasing passenger evacuation and survival time following an accident has received considerable publicity and has been the subject of testing by the regulatory agencies in both the United States and Europe. A test program, initiated by the CAA in 1987, involved the regulatory bodies in both Europe and North America in a collaborative research effort to determine the benefits and 'disbenefits' (disadvantages) of a CWSS. In order to obtain a balanced opinion of an onboard CWSS, NASA, and FAA requested the Boeing Commercial Airplane Group to investigate the potential 'disbenefits' of the proposed system from the perspective of the manufacturer and an operator. This report is the result of a year-long, cost-sharing contract study between the Boeing Commercial Airplane Group, NASA, and FAA. Delta Air Lines participated as a subcontract study team member and investigated the 'return to service' costs for an aircraft that would experience an uncommanded operation of a CWSS without the presence of fire. Disbenefits identified include potential delays in evacuation, introduction of 'common cause failure' in redundant safety of flight systems, physiological problems for passengers, high cost of refurbishment for inadvertent discharge, and potential to negatively affect other safety systems