Automated reduction of instantaneous flow field images

An automated data reduction system for the analysis of interference fringe patterns obtained using the particle image velocimetry technique is described. This system is based on digital image processing techniques that have provided the flexibility and speed needed to obtain more complete automation of the data reduction process. As approached here, this process includes scanning/searching for data on the photographic record, recognition of fringe patterns of sufficient quality, and, finally, analysis of these fringes to determine a local measure of the velocity magnitude and direction. The fringe analysis as well as the fringe image recognition are based on full frame autocorrelation techniques using parallel processing capabilities

A Case Study in the Superiority of the Purposive Approach to Statutory Interpretation: \u3cem\u3e Bruesewitz v. Wyeth \u3c/em\u3e

This Article uses the Supreme Court’s 2011 decision in Bruesewitz v. Wyeth to examine the textualist or “plain meaning” approach to statutory interpretation. For more than a quarter-century, Justice Scalia has successfully promoted textualism, usually associated with conservatism, among his colleagues. In Bruesewitz, Scalia, writing for the majority, and his liberal colleague Justice Sotomayer, in dissent, both employed textualism to determine if the plaintiffs, whose child was allegedly harmed by a vaccine, could pursue common-law tort claims or whether their remedies were limited to those available under the no-fault compensation system established by the National Childhood Vaccine Injury Act. Despite these Justices’ common approach to statutory interpretation, they reached diametrically opposite conclusions in opinions that dissected the statutory language and quarreled over the meaning of “even though” and “if” clauses. In contrast, Justice Breyer employed a purposive or “purposes and objectives” approach to statutory interpretation. Rather than obsessing over the meaning of each and every phrase, Breyer looked at Congress’s goals in passing the Act. He recognized that Scalia’s conclusion was correct, not because of the supposedly “plain” meaning of specific language, but because this interpretation was the only one that enabled the alternative compensation system to function as Congress envisioned. Other scholars have analyzed Bruesewitz as a preemption case, but despite statutory interpretation’s inherently decisive role in express preemption cases, this is the first Article to highlight Bruesewitz as an illustration of the emptiness of textualism

WHAM Observations of H-Alpha, [S II], and [N II] toward the Orion and Perseus Arms: Probing the Physical Conditions of the Warm Ionized Medium

A large portion of the Galaxy (l = 123 deg to 164 deg, b = -6 deg to -35 deg), which samples regions of the Local (Orion) spiral arm and the more distant Perseus arm, has been mapped with the Wisconsin H-Alpha Mapper (WHAM) in the H-Alpha, [S II] 6716, and [N II] 6583 lines. Several trends noticed in emission-line investigations of diffuse gas in other galaxies are confirmed in the Milky Way and extended to much fainter emission. We find that the [S II]/H-Alpha and [N II]/H-Alpha ratios increase as absolute H-Alpha intensities decrease. For the more distant Perseus arm emission, the increase in these ratios is a strong function of Galactic latitude and thus, of height above the Galactic plane. The [S II]/[N II] ratio is relatively independent of H-Alpha intensity. Scatter in this ratio appears to be physically significant, and maps of it suggest regions with similar ratios are spatially correlated. The Perseus arm [S II]/[N II] ratio is systematically lower than Local emission by 10%-20%. With [S II]/[N II] fairly constant over a large range of H-Alpha intensities, the increase of [S II]/H-Alpha and [N II]/H-Alpha with |z| seems to reflect an increase in temperature. Such an interpretation allows us to estimate the temperature and ionization conditions in our large sample of observations. We find that WIM temperatures range from 6,000 K to 9,000 K with temperature increasing from bright to faint H-Alpha emission (low to high [S II]/H-Alpha and [N II]/H-Alpha) respectively. Changes in [S II]/[N II] appear to reflect changes in the local ionization conditions (e.g. the S+/S++ ratio). We also measure the electron scale height in the Perseus arm to be 1.0+/-0.1 kpc, confirming earlier, less accurate determinations.Comment: 28 pages, 10 figures. Figures 2 and 3 are full color--GIFs provided here, original PS figures at link below. Accepted for publication in ApJ. More information about the WHAM project can be found at http://www.astro.wisc.edu/wham/ . REVISION: Figure 6, bottom panel now contains the proper points. No other changes have been mad

An exploratory randomised controlled trial comparing the effectiveness of different duration of canine-assisted interventions in higher education students

The aim of this study was to explore whether different durations of canine-assisted intervention (CAI) influenced the beneficial effects of CAI on anxiety, stress, depression, and the well-being of higher education (HE) students. Eighty-eight participants took part in an exploratory randomised control trial (RCT) and were assigned to the 2, 5, and 10-min CAI groups who interacted with a canine, or a control group who watched an unrelated slideshow. Pre- and post-intervention anxiety, stress, depression, and well-being levels were measured. Additionally, the type of interaction between humans and canines was recorded as well as participants’ views of the canines’ neoteny (juvenile features) to explore whether interaction activity and canine features have an impact on the beneficial positive effects of CAI. The results showed no differences in the duration of CAI in reducing anxiety, stress, and depression, meaning a 2-min CAI session was as effective as a 10-min session. The results also found individual intervention activities between humans and canines did not predict a reduction in anxiety, stress, depression, or an increase in general well-being. Additionally, a negative correlation was found between the cuteness of the canine and anxiety, and between the cuddliness of the canine and stress, although these results should be interpreted with caution due to high canine trait scores. Overall, this study used a CAI and control group to explore the differences between a single 2, 5, and 10-min CAI sessions in HE students and demonstrated a 2-min CAI session was as effective as a longer 10-min CAI session in supporting the mental health of HE students, by reducing anxiety, stress, and depression levels in the treatment group

Canine-assisted intervention reduces anxiety and stress in higher education students: a randomized controlled trial

The purpose of this study was to explore benefits of interacting with a canine on anxiety, stress, depression, and wellbeing in Higher Education (HE) students. Sixty participants took part in a randomized controlled trial. Assigned to either the canine-assisted intervention (CAI) or control group, the CAI group interacted with a canine whereas the control group watched an unrelated slideshow. Anxiety, depression, stress, and wellbeing measures were completed pre- and post-intervention and demonstrated there was a significant decrease in anxiety and stress in the CAI group. Due to group differences pre-intervention, findings for depression measures were uninterpretable and there was no significant effect found for general wellbeing. Overall, this study uses a CAI and control group and explores the use of a singular, brief CAI session in HE students demonstrating CAI to be an effective means of supporting mental health by decreasing levels of anxiety and stress in the treatment group

The discovery of novel recessive genetic disorders in dairy cattle : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science at AL Rae Centre of Genetics and Breeding, Massey University, Palmerston North, New Zealand

The selection of desirable characteristics in livestock has resulted in the transmission of advantageous genetic variants for generations. The advent of artificial insemination has accelerated the propagation of these advantageous genetic variants and led to tremendous advances in animal productivity. However, this intensive selection has led to the rapid uptake of deleterious alleles as well. Recently, a recessive mutation in the GALNT2 gene was identified to dramatically impair growth and production traits in dairy cattle causing small calf syndrome. The research presented here seeks to further investigate the presence and impact of recessive mutations in dairy cattle. A primary aim of genetics is to identify causal variants and understand how they act to manipulate a phenotype. As datasets have expanded, larger analyses are now possible and statistical methods to discover causal mutations have become commonplace. One such method, the genome-wide association study (GWAS), presents considerable exploratory utility in identifying quantitative trait loci (QTL) and causal mutations. GWAS' have predominantly focused on identifying additive genetic effects assuming that each allele at a locus acts independently of the other, whereas non-additive effects including dominant, recessive, and epistatic effects have been neglected. Here, we developed a single-locus non-additive GWAS model intended for the detection of dominant and recessive genetic mechanisms. We applied our non-additive GWAS model to growth, developmental, and lactation phenotypes in dairy cattle. We identified several candidate causal mutations that are associated with moderate to large deleterious recessive disorders of animal welfare and production. These mutations included premature-stop (MUS81, ITGAL, LRCH4, RBM34), splice disrupting (FGD4, GALNT2), and missense (PLCD4, MTRF1, DPF2, DOCK8, SLC25A4, KIAA0556, IL4R) variants, and these occur at surprisingly high frequencies in cattle. We further investigated these candidates for anatomical, molecular, and metabolic phenotypes to understand how these disorders might manifest. In some cases, these mutations were analogous to disorder-causing mutations in other species, these included: Coffin-Siris syndrome (DPF2); Charcot Marie Tooth disease (FGD4); a congenital disorder of glycosylation (GALNT2); hyper Immunoglobulin-E syndrome (DOCK8); Joubert syndrome (KIAA0556); and mitochondrial disease (SLC25A4). These discoveries demonstrate that deleterious recessive mutations exist in dairy cattle at remarkably high frequencies and we are able to detect these disorders through modern genotyping and phenotyping capabilities. These are important findings that can be used to improve the health and productivity of dairy cattle in New Zealand and internationally