129,189 research outputs found
Reply to Comment on "Circular Motion of Asymmetric Self-Propelling Particles"
In a Comment [Phys. Rev. Lett. 113, 029801 (2014)] on our Letter on
self-propelled asymmetric particles [Phys. Rev. Lett. 110, 198302 (2013);
arXiv:1302.5787], Felderhof claims that our theory based on Langevin equations
would be conceptually wrong. In this Reply we show that our theory is
appropriate, consistent, and physically justified.Comment: 2 page
UD\u27s Father Roesch Accepts Temporary Post in Hawaii
News release announces the Rev. Raymond A. Roesch, S.M., has accepted the position of acting president of Chaminade University in Hawaii
Identifying Interaction Sites in "Recalcitrant" Proteins: Predicted Protein and Rna Binding Sites in Rev Proteins of Hiv-1 and Eiav Agree with Experimental Data
Protein-protein and protein nucleic acid interactions are vitally important
for a wide range of biological processes, including regulation of gene
expression, protein synthesis, and replication and assembly of many viruses. We
have developed machine learning approaches for predicting which amino acids of
a protein participate in its interactions with other proteins and/or nucleic
acids, using only the protein sequence as input. In this paper, we describe an
application of classifiers trained on datasets of well-characterized
protein-protein and protein-RNA complexes for which experimental structures are
available. We apply these classifiers to the problem of predicting protein and
RNA binding sites in the sequence of a clinically important protein for which
the structure is not known: the regulatory protein Rev, essential for the
replication of HIV-1 and other lentiviruses. We compare our predictions with
published biochemical, genetic and partial structural information for HIV-1 and
EIAV Rev and with our own published experimental mapping of RNA binding sites
in EIAV Rev. The predicted and experimentally determined binding sites are in
very good agreement. The ability to predict reliably the residues of a protein
that directly contribute to specific binding events - without the requirement
for structural information regarding either the protein or complexes in which
it participates - can potentially generate new disease intervention strategies.Comment: Pacific Symposium on Biocomputing, Hawaii, In press, Accepted, 200
Measurement of the Total Cross Section for Hadronic Production by e+e- Annihilation at Energies between 2.6-5 Gev
Using the upgraded Beijing Spectrometer (BESII), we have measured the total
cross section for annihilation into hadronic final states at
center-of-mass energies of 2.6, 3.2, 3.4, 3.55, 4.6 and 5.0 GeV. Values of ,
, are determined.Comment: Submitted to Phys. Rev. Let
Interview with Wallace Fukunaga
The Rev. Wallace Fukunaga served as the campus minister of the United Church of Christ, overseeing the ministry of the Off Center Coffeehouse from 1965 to 1972. The Off Center Coffee House became a major center for debates and meetings of groups, including gatherings by Kokua Hawaii members
Linear electric field frequency shift (important for next generation electric dipole moment searches) induced in confined gases by a magnetic field gradient
The search for particle electric dipole moments (edm) represents a most
promising way to search for physics beyond the standard model. A number of
groups are planning a new generation of experiments using stored gases of
various kinds. In order to achieve the target sensitivities it will be
necessary to deal with the systematic error resulting from the interaction of
the well-known field with
magnetic field gradients (often referred to as the geometric phase effect
(Commins, ED; Am. J. Phys. \QTR{bf}{59}, 1077 (1991), Pendlebury, JM
\QTR{em}{et al;} Phys. Rev. \QTR{bf}{A70}, 032102 (2004)). This interaction
produces a frequency shift linear in the electric field, mimicking an edm. In
this work we introduce an analytic form for the velocity auto-correlation
function which determines the velocity-position correlation function which in
turn determines the behavior of the frequency shift (Lamoreaux, SK and Golub,
R; Phys. Rev \QTR{bf}{A71}, 032104 (2005)) and show how it depends on the
operating conditions of the experiment. We also discuss some additional issues.Comment: 21 pages, 5 figure
- …