996 research outputs found

    On a shape adaptive image ray transform

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    A conventional approach to image analysis is to perform separately feature extraction at a low level (such as edge detection) and follow this with high level feature extraction to determine structure (e.g. by collecting edge points using the Hough transform. The original image Ray Transform (IRT) demonstrated capability to extract structures at a low level. Here we extend the IRT to add shape specificity that makes it select specific shapes rather than just edges, the new capability is achieved by addition of a single parameter that controls which shape is elected by the extended IRT. The extended approach can then perform low-and high-level feature extraction simultaneously. We show how the IRT process can be extended to focus on chosen shapes such as lines and circles. We confirm the new capability by application of conventional methods for exact shape location. We analyze performance with images from the Caltech-256 dataset and show that the new approach can indeed select chosen shapes. Further research could capitalize on the new extraction ability to extend descriptive capability

    Season- and depth-dependent variability of a demersal fish assemblage in a large fjord estuary (Puget Sound, Washington)

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    Fjord estuaries are common along the northeast Pacific coastline, but little information is available on fish assemblage structure and its spatiotemporal variability. Here, we examined changes in diversity metrics, species biomasses, and biomass spectra (the distribution of biomass across body size classes) over three seasons (fall, winter, summer) and at multiple depths (20 to 160 m) in Puget Sound, Washington, a deep and highly urbanized fjord estuary on the U.S. west coast. Our results indicate that this fish assemblage is dominated by cartilaginous species (spotted ratfish [Hydrolagus colliei] and spiny dogfish [Squalus acanthias]) and therefore differs fundamentally from fish assemblages found in shallower estuaries in the northeast Pacific. Diversity was greatest in shallow waters (80 m) that are more common in Puget Sound and that are dominated by spotted ratf ish and seasonally (fall and summer) by spiny dogfish. Strong depth-dependent variation in the demersal fish assemblage may be a general feature of deep fjord estuaries and indicates pronounced spatial variability in the food web. Future comparisons with less impacted fjords may offer insight into whether cartilaginous species naturally dominate these systems or only do so under conditions related to human-caused ecosystem degradation. Information on species distributions is critical for marine spatial planning and for modeling energy flows in coastal food webs. The data presented here will aid these endeavors and highlight areas for future research in this important yet understudied system

    Conformal electromagnetic wave propagation using primal mimetic finite elements

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    Elektromagnetische Wellenausbreitung bildet die physikalische Grundlage fรผr unzรคhlige Anwendungen in verschiedenen Bereichen der heutigen Welt. Um rรคumliche Szenarien zu modellieren, muss der kontinuierliche Raum in geeigneter Weise in ein Rechengebiet umgewandelt werden. รœblich diskretisierte Modelle โ€“ welche auf verschiedenen GrรถรŸen beruhen โ€“ berรผcksichtigen die Beziehungen zwischen Feldvariablen mittels Relationen, welche durch partielle Differentialgleichungen reprรคsentiert werden. Um mathematische Beziehungen zwischen abhรคngigen Variablen in zweckdienlicher Art nachzubilden, schaffen hyperkomplexe Zahlensysteme ein passendes alternatives Rahmenwerk. Dieser Ansatz bezweckt das Einbinden bestimmter Systemeigenschaften und umfasst zusรคtzlich zur Modellierung von Feldproblemen, bei denen alle Variablen vorkommen, auch vereinfachte Modelle. Um eine wettbewerbsfรคhige Alternative zur รผblichen numerischen Behandlung elektromagnetischer Felder in beobachtungsorientierter Weise darzubieten, wird das elektrische und magnetische Feld elektromagnetischer Wellenfelder als eine zusammengefasste FeldgrรถรŸe, eingebettet im Funktionenraum, verstanden. Dieses Vorgehen ist intuitiv, da beide Felder in der Elektrodynamik gemeinsam auftreten und direkt messbar sind. Der Schwerpunkt dieser Arbeit ist in zwei Ziele untergliedert. Auf der einen Seite wird ein umformuliertes Maxwell-System in einer metrikfreien Umgebung mittels dem sogenannten โ€žbikomplexen Ansatzโ€œ umfassend untersucht. Auf der anderen Seite wird eine mรถgliche numerische Implementierung hinsichtlich der Finite-Elemente-Methode auf modernem Wege durch Nutzung der diskreten รคuรŸeren Analysis mit Fokus auf Genauigkeitsbelange bewertet. Hinsichtlich der numerischen Genauigkeitsbewertung wird demonstriert, dass der vorgelegte Ansatz grundsรคtzlich eine hรถhere Exaktheit zeigt, wenn man ihn mit Formulierungen vergleicht, welche auf der Helmholtz-Gleichung beruhen. Diese Dissertation trรคgt eine generalisierte hyperkomplexe alternative Darstellung von gewรถhnlichen elektrodynamischen Ausdrucksweisen zum Themengebiet der Wellenausbreitung bei. Durch die Nutzung einer direkten Formulierung des elektrischen Feldes in Verbindung mit dem magnetischen Feld wird die Rechengenauigkeit von Randwertproblemen erhรถht. Um diese Genauigkeitserhรถhung zu erreichen, wird eine geeignete Erweiterung der de Rham-Kohomologie unterbreitet.Electromagnetic wave propagation provides the physical basis for countless applications in various subjects of todayโ€™s world. In order to model spatial scenarios, the continuous space must be converted to an appropriate computational domain. Ordinarily discretized models โ€“ which are based on distinct quantities โ€“ consider the connection between field variables by relations which are represented by partial differential equations. To reproduce mathematical relationships between dependent variables in a convenient manner, hypercomplex number systems build a suitable alternative framework. This approach aims to incorporate certain system properties and covers, in addition to the modeling of field problems where all variables are present, also simplified models. To provide a competitive alternative to the ordinary numerical handling of electromagnetic fields in an observation-based way, the electric and magnetic field of electromagnetic wave fields is understood as only one combined field variable embedded in the function space. This procedure is intuitive since both fields occur together in electrodynamics and are directly measureable. The focus of this thesis is twofold. On the one side, a reformulated Maxwell system is broadly investigated in a metric-free environment by the use of the so-called โ€bicomplex approachโ€. On the other side, a possible numerical implementation concerning the Finite Element Method is evaluated in a modern way by the use of discrete exterior calculus with focus on accuracy matters. Regarding the numerical accuracy evaluation, it is demonstrated that the presented approach yields a higher exactness in general when comparing it to formulations which are based on the Helmholtz equation. This thesis contributes generalized hypercomplex alternative representations of ordinary electrodynamic expressions to the topic of wave propagation. By the use of a direct formulation of the electric field in conjunction with the magnetic field, the computational accuracy of boundary value problems is improved. In order to achieve this increase of accuracy, an appropriate enhancement of the de Rham cohomology is proposed

    Jane Addams, Mary Richmond and Liberal Feminism: An Historical Analysis

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    This historical thesis analyzed records and archival information regarding feminism in American social work by contrasting two key historical figures, Mary Richmond and Jane Addams who were considered the matriarchs of the social work movement in the earliest part of the 20th century. The study examined the accomplishments of Ms. Addams and Ms. Richmond, their backgrounds and philosophies that helped shape their feminism, beliefs, and political work and the impact it had on social work as a profession. The research gathered attempted to answer the question of whether the work done by these two women meets the current criteria of liberal feminism. That criteria being the support of a woman\u27s capacity to reason, individuality, right to education, economic success, citizenship rights and political equality, reproductive rights and availability of social services. According to the research, Jane Addams and Mary Richmond do meet the definition of liberal feminism according to Saulnier (1996) through their work, self-report and the information gathered from other researchers. The implications for social work practice and policy are discussed

    ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ ๋ฌผ์งˆ์ด ์—ฌ๋Ÿฌ ์ƒ์•  ๋‹จ๊ณ„์˜ ์ œ๋ธŒ๋ผํ”ผ์‰ฌ์˜ ๊ฐ‘์ƒ์„ , ์‹ ๊ฒฝ ๋ฐ ์‹ ์žฅ์— ๋ฏธ์น˜๋Š” ๋…์„ฑ๊ณผ ๊ด€๋ จ ๊ธฐ์ „ ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ(๋ฐ•์‚ฌ) -- ์„œ์šธ๋Œ€ํ•™๊ต๋Œ€ํ•™์› : ๋ณด๊ฑด๋Œ€ํ•™์› ํ™˜๊ฒฝ๋ณด๊ฑดํ•™๊ณผ, 2022. 8. ์ตœ๊ฒฝํ˜ธ.์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ(organic UV filters)์€ ์ž์™ธ์„ ์ฐจ๋‹จ์ œ, ํ™”์žฅํ’ˆ, ํ—ค์–ด ์ œํ’ˆ์„ ํฌํ•จํ•œ ๊ฐœ์ธ์œ„์ƒ์šฉํ’ˆ์— ๋„๋ฆฌ ์‚ฌ์šฉ๋˜๊ณ  ์žˆ๋Š” ๋ฌผ์งˆ๊ตฐ์ด๋‹ค. ์ตœ๊ทผ, ์—ฌ๋Ÿฌ ๊ตญ๊ฐ€์—์„œ ๋„๋ฆฌ ์‚ฌ์šฉ๋˜๊ณ  ์žˆ๋Š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ธ ๋ฒค์กฐํŽ˜๋…ผ-3(benzophenone-3, BP-3) ๋ฐ ์˜ฅํ‹ธ๋ฉ”ํ†ก์‹œ์‹ ๋‚˜๋ฉ”์ดํŠธ(octyl methoxycinnamate, OMC)๊ฐ€ ํ•จ์œ ๋œ ์ž์™ธ์„ ์ฐจ๋‹จ์ œ ์‚ฌ์šฉ์„ ๊ธˆ์ง€ํ•˜์˜€์ง€๋งŒ, ์ž์™ธ์„ ์ฐจ๋‹จ์ œ ์™ธ์—๋„ ์—ฌ์ „ํžˆ ๋‹ค์–‘ํ•œ ์šฉ๋„๋กœ ๋งŽ์ด ์‚ฌ์šฉ๋˜๊ณ  ์žˆ๊ธฐ ๋•Œ๋ฌธ์— ์ƒ์ฒด์‹œ๋ฃŒ๋‚˜ ํ™˜๊ฒฝ ์ค‘์—์„œ ๊พธ์ค€ํžˆ ๊ฒ€์ถœ๋˜๊ณ  ์žˆ๋‹ค. ๋Œ€๋ถ€๋ถ„์˜ ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„ ์ฐจ๋‹จ๋ฌผ์งˆ์€ ํ”ผ๋ถ€์— ๋„ํฌ ํ›„ ์ „์‹ ํก์ˆ˜๊ฐ€ ๊ฐ€๋Šฅํ•˜๊ธฐ ๋•Œ๋ฌธ์— ์ฃผ์˜๊ฐ€ ํ•„์š”ํ•˜๋‹ค. ๊ธฐ์กด ์—ญํ•™ ์—ฐ๊ตฌ๋“ค์— ๋”ฐ๋ฅด๋ฉด, ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์˜ ๋…ธ์ถœ์ด ๊ฐ‘์ƒ์„  ๋‚ด๋ถ„๋น„๊ณ„๋ฅผ ํฌํ•จํ•˜์—ฌ ๋‹ค์–‘ํ•œ ๊ฑด๊ฐ• ์˜ํ–ฅ๋“ค์— ๋Œ€ํ•ด ๋ณด๊ณ ํ•ด์™”๋‹ค. ๊ทธ๋Ÿฌ๋‚˜, ๋…์„ฑํ•™์  ์ •๋ณด๋Š” ๋Œ€๋ถ€๋ถ„ BP-3์˜ ์ƒ์‹ ๋ฐ ์„ฑํ˜ธ๋ฅด๋ชฌ ๊ต๋ž€์— ๊ตญํ•œ๋˜์–ด ์žˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ๋“ค์€ ๊ตฌ์กฐ์  ์œ ์‚ฌ์„ฑ์œผ๋กœ ์ธํ•ด ๋น„์Šทํ•œ ์ˆ˜์ค€์˜ ๋…์„ฑ์˜ํ–ฅ์„ ์˜ˆ์ƒํ•  ์ˆ˜ ์žˆ์œผ๋ฉฐ, BP-3๋ฅผ ์ œ์™ธํ•œ ๋‚˜๋จธ์ง€ ๋ฌผ์งˆ์— ๋Œ€ํ•œ ๋…์„ฑ์—ฐ๊ตฌ๋Š” ๋ถ€์กฑํ•œ ์ˆ˜์ค€์ด๋‹ค. ํŠนํžˆ, ์—ฌ๋Ÿฌ ์ƒ์• ์ฃผ๊ธฐ์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ ์—ฐ๊ตฌ๋Š” ๋งค์šฐ ๋ถ€์กฑํ•˜๋‹ค. ๋”ฐ๋ผ์„œ, ๋ณธ ์—ฐ๊ตฌ๋Š” ์—ฌ๋Ÿฌ ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ ๋…ธ์ถœ์— ๋”ฐ๋ฅธ ๊ฐ‘์ƒ์„  ๋‚ด๋ถ„๋น„๊ณ„ ๊ต๋ž€๊ณผ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ ๊ต๋ž€๊ณผ ๊ด€๋ จ๋œ ๊ด€๋ จ ๋…์„ฑ ์˜ํ–ฅ์„ ํŒŒ์•…ํ•˜๊ณ ์ž ํ•œ๋‹ค. ์ฒซ๋ฒˆ์งธ ์—ฐ๊ตฌ์—์„œ๋Š”(Chapter 1) ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์˜ ํ˜„์žฌ ์‚ฌ์šฉ ๋ฐ ์ƒ์‚ฐ๋Ÿ‰, ๊ด€๋ จ ๊ทœ์ œ์— ๋Œ€ํ•ด ์กฐ์‚ฌํ•˜๊ณ  ์ด ๋ฌผ์งˆ๋“ค์˜ ๋…์„ฑํ•™์  ์ง€์‹ ๊ฐญ์„ ํ™•์ธํ•˜๊ธฐ ์œ„ํ•ด ๋ฐ ๋‚ด๋ถ„๋น„๊ณ„ ๊ต๋ž€ ๊ฐ€๋Šฅ์„ฑ์— ๋Œ€ํ•ด ์กฐ์‚ฌํ•˜์˜€๋‹ค. ํ™˜๊ฒฝ ์ค‘ ๊ฒ€์ถœ ๋†๋„ ๋ฐ ์ƒํƒœํ•™์  ์ค‘์š”์„ฑ์„ ๊ณ ๋ คํ•˜์—ฌ ์•„๋ณด๋ฒค์กด(avobenzone, AVB), BP-3, ์˜ฅํ† ํฌ๋ฆด๋ Œ(octocrylene, OC), OMC๋ฅผ ์„ ์ •ํ•˜์˜€๋‹ค. ๋‘ ๋ฒˆ์งธ ์—ฐ๊ตฌ(Chapter 2)์—์„œ๋Š” ๊ธ€๋กœ๋ฒŒ ์‹œ์žฅ์—์„œ ์ฃผ๋กœ ๋งŽ์ด ์‚ฌ์šฉ๋˜๋ฉฐ ํ™˜๊ฒฝ ์ค‘ ๊ฒ€์ถœ๋นˆ๋„๊ฐ€ ๋†’์€ AVB, BP-3, OC, ๊ทธ๋ฆฌ๊ณ  OMC 4์ข…์„ ๋Œ€์ƒ์œผ๋กœ ์ œ๋ธŒ๋ผํ”ผ์‰ฌ ๋ชจํ˜•์„ ์ด์šฉํ•˜์—ฌ ์ด๋“ค ๋ฌผ์งˆ์˜ ๊ฐ‘์ƒ์„  ํ˜ธ๋ฅด๋ชฌ ๊ต๋ž€ ๊ฐ€๋Šฅ์„ฑ์„ ๋ฐฐ์•„ ๋ฐœ๋‹ฌ์‹œ๊ธฐ(์ˆ˜์ • ํ›„ 120 ์‹œ๊ฐ„ ๋…ธ์ถœ), ์ดˆ๊ธฐ ๋ฐœ๋‹ฌ๋‹จ๊ณ„(์ˆ˜์ • ํ›„ 30์ผ ๋…ธ์ถœ), ์„ฑ์–ด ์‹œ๊ธฐ(6๊ฐœ์›”๋ น ์ด์ƒ์˜ ์ˆ˜์ปท, 21์ผ ๋…ธ์ถœ)์˜ ์—ฌ๋Ÿฌ ์ƒ์• ์ฃผ๊ธฐ์—์„œ ์‚ดํŽด๋ณด์•˜๋‹ค. ๋…ธ์ถœ ์ข…๋ฃŒ ํ›„, ํšจ์†Œ ๊ฒฐํ•ฉ ๋ฉด์—ญ ํก์ฐฉ๋ฒ•(ELISA)์„ ํ†ตํ•ด ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ ์ž๊ทน ํ˜ธ๋ฅด๋ชฌ(TSH) ๋ฐ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ(T4, T3)์˜ ๋ณ€ํ™”์™€ ์‹ค์‹œ๊ฐ„ ์ค‘ํ•ฉํšจ์†Œ ์—ฐ์‡„๋ฐ˜์‘(RT-qPCR)์„ ์ด์šฉํ•˜์—ฌ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ ์กฐ์ ˆ๊ณผ ๊ด€๋ จ๋œ ์œ ์ „์ž(trh, trhr, tshฮฒ, tshr, nis, tpo, tg, dio1, dio2, dio3, trฮฑ, trฮฒ, ugt1ab, sult1 st5, ttr)๋ฅผ ๋ถ„์„ํ•˜์˜€๋‹ค. ๊ทธ ๊ฒฐ๊ณผ, ์—ฐ๊ตฌ ๋Œ€์ƒ ๋ฌผ์งˆ 4์ข… ๋ชจ๋‘(AVB, BP-3, OC, OMC) ์ œ๋ธŒ๋ผํ”ผ์‰ฌ์˜ ๋ชจ๋“  ์ƒ์• ์ฃผ๊ธฐ์˜ ์‹œ์ƒํ•˜๋ถ€-๋‡Œํ•˜์ˆ˜์ฒด ๊ฐ‘์ƒ์„ (hypothalamus-pituitary thyroid axis, HPT) ์ถ•๊ณผ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ์˜ ๊ฐ„ ๋Œ€์‚ฌ์™€ ๊ด€๋ จ๋œ ์œ ์ „์ž์˜ ๋ฐœํ˜„ ๋ณ€ํ™”๊ฐ€ ๊ด€์ฐฐ๋˜์—ˆ๋‹ค. ํŠนํžˆ, ๋ฐฐ์•„ ๋ฐœ๋‹ฌ๋‹จ๊ณ„์™€ ์œ ์–ด ์‹œ๊ธฐ์— ๊ทธ ์˜ํ–ฅ์ด ๋” ํฌ๊ฒŒ ๋‚˜ํƒ€๋‚œ ๊ฒƒ์„ ํ™•์ธํ•˜์˜€๋‹ค. ๋”ฐ๋ผ์„œ ๋‘ ๋ฒˆ์งธ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋ฅผ ์ข…ํ•ฉํ•ด ๋ณผ ๋•Œ, ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ด ์—ฌ๋Ÿฌ ์ƒ์•  ๋‹จ๊ณ„์— ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ์˜ ๋ถˆ๊ท ํ˜•์„ ์ผ์œผํ‚ค๋Š” ๊ฒƒ์„ ํ™•์ธํ•˜์˜€๋‹ค. ์„ธ ๋ฒˆ์งธ ์—ฐ๊ตฌ(Chapter 3)์—์„œ๋Š” ๋ฐฐ์•„ ๋ฐœ๋‹ฌ์‹œ๊ธฐ(์ˆ˜์ • ํ›„ 120 ์‹œ๊ฐ„ ๋…ธ์ถœ), ์ดˆ๊ธฐ ๋ฐœ๋‹ฌ๋‹จ๊ณ„(์ˆ˜์ • ํ›„ 30์ผ ๋…ธ์ถœ), ์„ฑ์–ด ์‹œ๊ธฐ(6๊ฐœ์›”๋ น ์ด์ƒ์˜ ์ˆ˜์ปท, 21์ผ ๋…ธ์ถœ)์˜ ์—ฌ๋Ÿฌ ์ƒ์• ์ฃผ๊ธฐ์—์„œ ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์— ๋Œ€ํ•œ ์‹ ๊ฒฝ ๋…์„ฑ์„ ํ‰๊ฐ€ํ•˜๊ธฐ ์œ„ํ•ด ์ˆ˜ํ–‰๋˜์—ˆ๋‹ค. ์ œ๋ธŒ๋ผํ”ผ์‰ฌ๋ฅผ ๋ฐฐ์•„๋‹จ๊ณ„๋ถ€ํ„ฐ ์ˆ˜์ • ํ›„ 120์‹œ๊ฐ„ ๋ฐ 30์ผ ๋™์•ˆ, ํ‰๊ฐ€ ๋Œ€์ƒ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์— ๋…ธ์ถœํ•œ ํ›„, Daniovision ethovisionยฎ (Nodulus)์„ ์ด์šฉํ•˜์—ฌ ๋น› ์ž๊ทน์œผ๋กœ ์ธํ•œ ํ–‰๋™ ๋ณ€ํ™”(hyper-, hypoactivity)์™€ ๋ถˆ์•ˆ์žฅ์•  ํ‘œํ˜„ํ˜•์ธ ์‹ ๊ฒฝํ–‰๋™ํ•™์  ๋ณ€ํ™”์™€ ํ•จ๊ป˜ ์‹ ๊ฒฝ๋ฐœ๋‹ฌ ๋ฐ ์‹ ๊ฒฝ ๋…์„ฑ๊ณผ ๊ด€๋ จ๋œ ์œ ์ „์ž ๋งˆ์ปค(mbp, gap43, gfap, c-fos, syn2a, syt1a, stxbp1b)๋ฅผ ๋ถ„์„ํ•˜์˜€๋‹ค. ๋˜ํ•œ, ์ œ๋ธŒ๋ผํ”ผ์‰ฌ ์ˆ˜์ปท ์„ฑ์–ด๋ฅผ ์ด์šฉํ•˜์—ฌ 21์ผ๊ฐ„ ํ‰๊ฐ€ ๋Œ€์ƒ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์— ๋…ธ์ถœ ํ›„ ๋งˆ์ฐฌ๊ฐ€์ง€๋กœ ์‹ ๊ฒฝ๋ฐœ๋‹ฌ ๋ฐ ๋…์„ฑ๊ณผ ๊ด€๋ จ๋œ ์œ ์ „์ž์˜ ๋ฐœํ˜„ ๋ณ€ํ™”๋ฅผ ํ™•์ธํ•˜์˜€๋‹ค. ๊ทธ ๊ฒฐ๊ณผ, ๋ฐฐ์•„ ๋ฐœ๋‹ฌ ๋ฐ ์ดˆ๊ธฐ ๋ฐœ๋‹ฌ์‹œ๊ธฐ์˜ ํ–‰๋™์ด ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์˜ ๋…ธ์ถœ๋กœ ์ธํ•ด ๋Œ€์กฐ๊ตฐ์— ๋น„ํ•ด ์œ ์˜ํ•˜๊ฒŒ ๊ฐ์†Œํ•˜์˜€๊ณ , ๋ถˆ์•ˆ์žฅ์• ์˜ ์‹ ๊ฒฝํ–‰๋™ํ•™์  ๋ณ€ํ™”๊ฐ€ ์œ ์˜ํ•˜๊ฒŒ ๋‚˜ํƒ€๋‚ฌ๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋ฅผ ํ†ตํ•ด ์‹ ๊ฒฝํ–‰๋™ํ•™์  ๋ณ€ํ™”๋Š” ์ค‘์ถ” ์‹ ๊ฒฝ๊ณ„์— ๋ฐœํ˜„๋˜๋Š” ์ฃผ์š” ์œ ์ „์ž ๋˜๋Š” ์‹ ๊ฒฝ ์„ธํฌ์— ๋Œ€ํ•œ ์ง๊ฐ„์ ‘์ ์ธ ๋…์„ฑ ์˜ํ–ฅ์˜ ๊ฒฐ๊ณผ์ผ ๊ฐ€๋Šฅ์„ฑ์„ ์‹œ์‚ฌํ•œ๋‹ค. ์‹ ๊ฒฝ๋ฐœ๋‹ฌ ๋ฐ ๋…์„ฑ๊ณผ ๊ด€๋ จ๋œ ์œ ์ „์ž์˜ ๋ฐœํ˜„์€ ๋ชจ๋“  ์ƒ์— ์ฃผ๊ธฐ์—์„œ ์˜ํ–ฅ์ด ๋‚˜ํƒ€๋‚ฌ์ง€๋งŒ, ๊ทธ ์ค‘ ๋ฐœ๋‹ฌ๋‹จ๊ณ„๊ฐ€ ๊ฐ€์žฅ ํฌ๊ฒŒ ์˜ํ–ฅ์„ ๋ฐ›์•˜๋‹ค. ๋”ฐ๋ผ์„œ, ์ด ์—ฐ๊ตฌ๋ฅผ ํ†ตํ•ด ๊ด€์ฐฐ๋œ ์‹ ๊ฒฝํ–‰๋™ํ•™์  ๋ณ€ํ™”๋Š” ์ค‘์ถ” ์‹ ๊ฒฝ์˜ ์ฃผ์š” ์œ ์ „์ž์˜ ๋ฐœํ˜„์— ์ง์ ‘์ ์ธ ์˜ํ–ฅ์„ ๋ฏธ์น  ์ˆ˜ ์žˆ์Œ์„ ์‹œ์‚ฌํ•œ๋‹ค. ๋งˆ์ง€๋ง‰์œผ๋กœ, ๋„ค ๋ฒˆ์งธ ์—ฐ๊ตฌ(Chapter 4)์—์„œ๋Š” ๋ฐฐ์•„ ๋ฐœ๋‹ฌ์‹œ๊ธฐ(์ˆ˜์ • ํ›„ 120 ์‹œ๊ฐ„ ๋…ธ์ถœ), ์ดˆ๊ธฐ ๋ฐœ๋‹ฌ๋‹จ๊ณ„(์ˆ˜์ • ํ›„ 30์ผ ๋…ธ์ถœ), ์„ฑ์–ด ์‹œ๊ธฐ(6๊ฐœ์›”๋ น ์ด์ƒ์˜ ์ˆ˜์ปท, 21์ผ ๋…ธ์ถœ)์˜ ์—ฌ๋Ÿฌ ์ƒ์• ์ฃผ๊ธฐ์—์„œ ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ด ์‹ ์žฅ๊ธฐ๋Šฅ์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ์— ๋Œ€ํ•ด ํ‰๊ฐ€ํ•˜์˜€๋‹ค. ๋…ธ์ถœ ์ข…๋ฃŒ ํ›„, ์ œ๋ธŒ๋ผํ”ผ์‰ฌ ๋ฐฐ์•„ ๋ฐ ์œ ์–ด๋ฅผ ๊นจ๋—ํ•œ ์‚ฌ์œก์ˆ˜๋กœ ์˜ฎ๊ธด ํ›„ ๋‹จ๋ฐฑ๋‡จ ์ˆ˜์ค€์„ ๊ด€์ฐฐํ•˜์˜€๋‹ค. ๋˜ํ•œ, ์‹ ์žฅ์žฌ์ƒ๊ณผ ๊ตฌ์กฐ์— ์ค‘์š”ํ•œ ์—ญํ• ์„ ํ•˜๋Š” ํ•ต์‹ฌ ์œ ์ „์ž์˜ ๋ฐœํ˜„ ๋ณ€ํ™”๋ฅผ ๊ด€์ฐฐํ•˜๊ธฐ ์œ„ํ•ด ๋ฐฐ์•„ ๋ฐœ๋‹ฌ ๋ฐ ์œ ์–ด ์‹œ๊ธฐ์—์„œ๋Š” ์‹ ์žฅ ํŠน์ด์ ์œผ๋กœ ๋ฐœํ˜„๋˜๋Š” ์œ ์ „์ž(wt1a, podocin, nephrin, kim-1, cdh17, sim1a)๋ฅผ ๋ถ„์„ํ•˜์˜€๊ณ , ์ˆ˜์ปท ์„ฑ์–ด ์‹ ์žฅ ์กฐ์ง์„ ์ด์šฉํ•˜์—ฌ ๋ณด๋‹ค ๋” ์ž์„ธํ•œ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ๋กœ ์ธํ•œ ์‹ ์žฅ๋…์„ฑ ๊ธฐ์ „์„ ํŒŒ์•…ํ•˜๊ธฐ ์œ„ํ•ด ์—ฌ๋Ÿฌ ์œ ์ „์ž(ppargc1a, tbx2a, tbx2b, etv4, etv5, wt1a, podocin, nephrin, kim-1, cdh17, sim1a, pax2a)๋ฅผ ์ด์šฉํ•˜์—ฌ ๋ถ„์„ํ•˜์˜€๋‹ค. ๊ทธ ๊ฒฐ๊ณผ, ๋ฐฐ์•„ ๋ฐœ๋‹ฌ ๋ฐ ์œ ์–ด ์‹œ๊ธฐ์˜ ์ œ๋ธŒ๋ผํ”ผ์‰ฌ์˜ ๋‹จ๋ฐฑ๋‡จ ์ˆ˜์ค€์— ๋ณ€ํ™”์™€ ์‹ ์žฅ ๊ตฌ์กฐ ๋ฐ ๊ธฐ๋Šฅ์— ์ค‘์š”ํ•œ ์—ญํ• ์„ ํ•˜๋Š” ์ฃผ์š” ์œ ์ „์ž์˜ ๋ฐœํ˜„์˜ ๋ณ€ํ™”๊ฐ€ ๊ด€์ฐฐ๋˜์—ˆ๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋ฅผ ํ†ตํ•ด ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์˜ ๋…ธ์ถœ์ด ์—ฌ๋Ÿฌ ์ƒ์•  ๋‹จ๊ณ„(๋ฐฐ์•„๋ฐœ๋‹ฌ, ์œ ์–ด ๋ฐ ์„ฑ์–ด ์‹œ๊ธฐ)์˜ ์‹ ์žฅ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฒƒ์„ ๋ณด์—ฌ์ฃผ์–ด ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ ๋…ธ์ถœ๋กœ ์ธํ•œ ์‹ ์žฅ ๊ฑด๊ฐ• ์˜ํ–ฅ์— ๋Œ€ํ•œ ์ค‘์š”ํ•œ ์‹ค๋งˆ๋ฆฌ๋ฅผ ์ œ๊ณตํ•œ๋‹ค. ์ด์ƒ์˜ ์„ธ ์‹คํ—˜ ์—ฐ๊ตฌ๋ฅผ ์ข…ํ•ฉํ•ด๋ณด์•˜์„ ๋•Œ, ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ(AVB, BP-3, OC, OMC)์˜ ์ค‘์š”ํ•œ ๊ฑด๊ฐ• ์˜ํ–ฅ์„ ๋ณด์—ฌ์ฃผ์—ˆ๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋ฅผ ํ†ตํ•ด ์—ฐ๊ตฌ ๋Œ€์ƒ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ด ์ œ๋ธŒ๋ผํ”ผ์‰ฌ์˜ ์—ฌ๋Ÿฌ ์ƒ์•  ๋‹จ๊ณ„์˜ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ์˜ ํ•ญ์ƒ์„ฑ์— ์˜ํ–ฅ์„ ์ฃผ์—ˆ๋‹ค. ๋” ๋‚˜์•„๊ฐ€, ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์— ๋…ธ์ถœ๋œ ์ œ๋ธŒ๋ผํ”ผ์‰ฌ์˜ ์‹ ๊ฒฝํ–‰๋™ ๋ฐ ์‹ ์žฅ์˜ ๊ธฐ๋Šฅ์ด ์†์ƒ๋˜์—ˆ๋‹ค. ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์€ ํ”ผ๋ถ€์— ์˜ค๋žซ๋™์•ˆ ๋จธ๋ฌผ๋„๋ก ๋งŒ๋“ค์–ด์ง€๊ณ , ํ”ผ๋ถ€ํก์ˆ˜๋ฅผ ํ†ตํ•ด ์ˆœํ™˜๊ณ„์— ๋„๋‹ฌํ•  ์ˆ˜ ์žˆ๊ธฐ ๋•Œ๋ฌธ์— ์‚ฌ๋žŒ์˜ ๊ฑด๊ฐ•์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ์€ ํ™˜๊ฒฝ ๋ณด๊ฑดํ•™์ ์œผ๋กœ ๋งค์šฐ ์ค‘์š”ํ•˜๋‹ค. ๋งŽ์€ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ด ํ˜ผํ•ฉ๋˜์–ด ์‚ฌ์šฉ๋˜๋Š” ํŠน์„ฑ์„ ๊ณ ๋ คํ•˜๋ฉด, ์ด ๋ฌผ์งˆ๋“ค์˜ ํ˜ผํ•ฉ๋…์„ฑ์„ ์ดํ•ดํ•˜๋Š” ๊ฒƒ์ด ํ•„์š”ํ•˜๋‹ค. ๊ณ ๋†๋„ ๋…ธ์ถœํ™˜๊ฒฝ์œผ๋กœ ์ œํ•œ๋˜๊ธฐ๋Š” ํ•˜์ง€๋งŒ, ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์€ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ ๊ต๋ž€ ์ž‘์šฉ์ด ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์œผ๋ฉฐ, ๊ทธ ๋ฐ˜์‘์ด ๋…ธ์ถœ ์‹œ๊ธฐ๋ณ„๋กœ ๋‹ค๋ฅด๊ฒŒ ๊ด€์ฐฐ๋˜์—ˆ๋‹ค. ์ด๋Š” ํ‰๊ฐ€ ๋Œ€์ƒ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์ด HPT ์ถ• ๋ฐ ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ์˜ ๊ฐ„ ๋Œ€์‚ฌ์— ์ง์ ‘ ์ž‘์šฉํ•˜๋Š” ๊ธฐ์ „์— ์˜ํ•œ ํ˜„์ƒ์œผ๋กœ ๋ณผ ์ˆ˜ ์žˆ๋‹ค. ๋˜ํ•œ, ์—ฌ๋Ÿฌ ์ƒ์•  ์ฃผ๊ธฐ์— ์‹ ๊ฒฝ๊ณผ ์‹ ์žฅ์˜ ์ •์ƒ์ ์ธ ๊ธฐ๋Šฅ์„ ์†์ƒ์‹œํ‚ค๋Š” ๊ฒƒ์œผ๋กœ ๋ณด์ธ๋‹ค. ์ฃผ์š” ์œ ๊ธฐ๊ณ„ ์ž์™ธ์„  ์ฐจ๋‹จ ๋ฌผ์งˆ์ด ๊ฐ‘์ƒ์„ ํ˜ธ๋ฅด๋ชฌ ๋ฐ ๊ด€๋ จ ๊ฑด๊ฐ•์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ์„ ํŒŒ์•…ํ•˜๋Š” ๊ฒƒ์€ ํ™˜๊ฒฝ๋ณด๊ฑดํ•™์ ์ธ ์ธก๋ฉด์—์„œ ๋งค์šฐ ์ค‘์š”ํ•˜๋ฉฐ, ์•ˆ์ „ํ•œ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ์„ ์„ ์ •ํ•˜๊ธฐ ์œ„ํ•œ ๊ณผํ•™์ ์ธ ๊ธฐ์ดˆ์ž๋ฃŒ๋กœ๋„ ๋งค์šฐ ์ค‘์š”ํ•  ๊ฒƒ์ด๋‹ค. ๋‚˜์•„๊ฐ€, ๋งŽ์€ ์ž์™ธ์„  ์ฐจ๋‹จ ๋ฌผ์งˆ์ด ํ˜ผํ•ฉ๋˜์–ด ์‚ฌ์šฉ๋˜๋Š” ํŠน์„ฑ์„ ๊ณ ๋ คํ•˜๋ฉด, ์ด ๋ฌผ์งˆ๋“ค์˜ ํ˜ผํ•ฉ ๋…์„ฑ์„ ์ดํ•ดํ•˜๋Š” ๊ฒƒ์ด ํ•„์š”ํ•˜๋ฉฐ, ๋ฐœ๋‹ฌ ์‹œ๊ธฐ์™€ ๊ฐ™์ด ๋ฏผ๊ฐํ•œ ์ง‘๋‹จ์—์„œ์˜ ์ž์™ธ์„  ์ฐจ๋‹จ๋ฌผ์งˆ๋กœ ์ธํ•œ ๊ฑด๊ฐ•์˜ํ–ฅ๊ณผ ๊ด€๋ จํ•œ ์‹คํ—˜ ๋ฐ ์—ญํ•™ ์กฐ์‚ฌ๊ฐ€ ํ•„์š”ํ•˜๋‹ค.Organic UV filters are widely used for skin protection in personal care products such as sunscreen, cosmetics, and hair products. Although several UV filter agents, such as benzophenone-3 (BP-3) and octyl methoxycinnamate (OMC), have been banned for use in sunscreens in some regions, many organic UV filters are still extensively used for various applications. Most organic UV filters can penetrate the skin following dermal application and reach the bloodstream at levels warranting caution. Growing laboratory and epidemiologic evidence shows that organic UV filter agents can affect the thyroid endocrine system and possibly affect behavior and damage the kidneys. However, toxicological information is mostly limited to the endocrine-disrupting effects of BP-3. Therefore, the present study aims to investigate thyroid endocrine disruption and related toxicities following exposure to different organic UV filters. In the first study (Chapter 1), to identify the knowledge gaps related to UV filters, we reviewed the current uses, regulations and known endocrine disrupting potencies of major organic UV filters. Considering environmental exposures and ecological significance, AVB, BP-3, OC and OMC were chosen as test UV filters for further toxicological evaluations. In the second study (Chapter 2), the effects of the โ€˜test UV filtersโ€™ on thyroid hormone dysregulation were evaluated in embryo-larval (~120 hours post-fertilization), early-life (~30 days post-fertilization), and adult (>6 months, 21-day exposure) male zebrafish (Danio rerio). After exposure, thyroid stimulating hormone (TSH) and thyroid hormones (T4 and T3) were measured with enzyme-linked immunosorbent assay (ELISA), and genes related to thyroid hormone regulation (trh, trhr, tshฮฒ, tshr, nis, tpo, tg, dio1, dio2, dio3, trฮฑ, trฮฒ, ugt1ab, sult1 st5, ttr) were evaluated by using real-time quantitative polymerase chain reaction (RTโ€“qPCR). After exposure to several UV filters, including AVB, BP-3, OC, and OMC, the levels of thyroid hormone and hypothalamus-pituitary thyroid (HPT) axis and hepatic metabolism genes were significantly altered in embryo-larval, juvenile and adult male zebrafish. Thus, our study suggests that commonly used UV filters could cause thyroid system imbalance in a life stage-specific manner. In addition, the results of this study indicate that early life stages are specifically vulnerable to UV filter exposure. In the third study (Chapter 3), the neurotoxicity of these UV filters was examined, and a possible link between thyroid hormone dysregulation and neurotoxicity was investigated in embryo-larval (~120 hours post-fertilization), early-life (~30 days post-fertilization), and adult (>6 months, 21 days of exposure) male zebrafish. Neurobehavioral changes in zebrafish were analyzed during open-field and novel tank tests using Daniovision Ethovisionยฎ (Nodulus). Hypo- or hyperactivity and thigmotaxis, which are anxiety-like behavior phenotypes, were also evaluated. The mRNA expression levels of neurogenesis and neurotoxic markers (mbp, gap43, gfap, c-fos, syn2a, syt1a, stxbp1b) were quantified to address possible underlying mechanisms. Neurobehavioral changes were observed, along with changes in key genes related to neurodevelopment or neurogenesis. Our results suggest that locomotion and anxiety-like behavior changes in embryo-larval and juvenile zebrafish are likely the result of altered gene expression in the central nervous system and/or direct neurotoxic effects on neuronal cells. Moreover, UV filter displayed stronger effects in terms of neurogenesis, which implies that the developing brain is particularly vulnerable to UV filter exposure. In the last study (Chapter 4), we demonstrated kidney toxicity caused by the study UV filters in embryo-larval (~120 hours post-fertilization), early-life (~30 days post-fertilization), and adult (>6 months, 21-day exposure) male zebrafish (Danio rerio). At the end of theexposure period, embryo-larval and juvenile fish were transferred to clean culture media for proteinuria analysis. The kidneys of the adult male zebrafish were harvested for histological observations. For nephrotoxicity- and nephrogenesis-related mRNA quantification, whole embryo-larval and juvenile zebrafish and the kidney tissues of adult male zebrafish were collected. In embryo-larval and juvenile fish, only genes that were expressed specifically in the kidneys were evaluated (wt1a, podocin, nephrin, kim-1, cdh17, sim1a). For adult male fish, genes known to play a role in nephrogenesis and kidney injury were analyzed (ppargc1a, tbx2a, tbx2b, etv4, etv5, wt1a, podocin, nephrin, kim-1, cdh17, sim1a, pax2a). Subsequently, it was found that exposure to UV filters induced significant changes in the proteinuria of embryonic larvae and zebrafish. In addition, transcriptional changes in genes related to kidney structure and injury were observed in embryo-larval, juvenile and adult zebrafish. The results from this study clearly demonstrate that exposure to UV filters increases kidney toxicity in a concentration-dependent manner during various life stages (e.g., embryo-larval, juvenile, and adult). This study provides important insights into kidney health consequences associated with UV filters. The series of studies demonstrated important health effects of UV filters. We found that many organic UV filters disrupt the thyroid hormone balance of the embryo-larval, early-life and adult stages of zebrafish. Moreover, these UV filters impaired neurobehavior and damaged the normal kidney function of the fish. Because UV filters are designed to stay on the skin for a long time and can penetrate the skin to reach the circulation, their effects on human health are of great public health concern. Moreover, many UV filters are used in combination with others, and hence, it is urgent to understand and model their combined toxicity to guarantee the safety of sunscreens. Finally, the consequences of UV filter exposure during susceptible periods, e.g., fetal life, infancy, and puberty, are in question and warrant rigorous experimental and epidemiologic investigations.Abstract 6 Contents 10 List of tables 12 List of figues 14 Chapter 1 Introduction 16 1.1 Background 16 1.2 Current uses and regulations 20 1.3 Physicochemical characteristics and environmental occurrences 31 1.4 Endocrine disrupting potencies 36 1.5 Summary 80 1.6 Research obsectives and study design 82 Chapter 2 Thyroid disruption of organic UV filters in different life stages of zeberafish (Danio rerio) 86 2.1 Introduction 86 2.2 Materials and methods 89 2.3 Results 99 2.4 Discussion 141 2.5 Summary 152 Chapter 3 Neurotoxicity and related mechanisms of organic UV filters in different life stages of zebrafish (Danio rerio) 153 3.1 Introduction 153 3.2 Materials and methods 157 3.3 Results 165 3.4 Discussion 184 3.5 Summary 191 Chapter 4 Kidney toxicity and related mechanisms of organic UV filters in different life stages of zebrafish (Danio rerio) 192 4.1 Introduction 192 4.2 Materials and methods 196 4.3 Results 206 4.4 Discussion 219 4.5 Summary 226 Chapter 5 Conclusions 227 5.1 Summary 227 5.2 Future research directions 253 References 255 ๊ตญ๋ฌธ ์ดˆ๋ก(Abstract in Korean) 294 ๊ฐ์‚ฌ์˜ ๊ธ€ 299๋ฐ•

    Targeting Gender: A Content Analysis of Alcohol Advertising in Magazines

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    Advertisers use different advertising strategies depending on their target audiences in order to maximize advertising effects. In general, the most frequently used target segmentation is gender because it meets requirements for successful advertising implementation. Thus, the focus of this study is to find whether advertisements contain ingredients that are likely to have special appeal for target audiences. The study analyzed message strategy and creative strategy of alcohol advertising in magazines. For the analysis, from January 2004 to December 2011, a total number of 474 alcohol advertisements were examined from six magazines divided by three categories: men (Playboy and Sports Illustrated), women (Southern Living and Vogue), and gender-neutral (Gourmet and Gentlemen\u27s Quarterly). The results of this study point out that alcohol advertising appeals to gender differences through different creative strategies rather than through message strategies. However, regardless of gender, the most commonly used strategies in alcohol advertising are to appeal to target audienceโ€™s emotional aspects, especially within social situations. Also, results reveal several characteristics of alcohol advertising in magazines such as womenโ€™s increasing socio-economic aspects and magazinesโ€™ media characteristics

    Compositional Techniques in Hodie by Ralph Vaughan Williams

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    Hodie (This day) is Vaughan Williams\u27s last large choral work. It is important because Vaughan Williams used not only complicated and innovative compositional techniques but also the largest instrumentation among his choral-orchestral compositions. It gives a challenging opportunity for composers who wish to learn innovative compositional techniques for vocal or choral-orchestral music. This research project will present Vaughan Williams\u27s compositional techniques in a major choral-orchestral composition consisting of multiple movements. First, unification as a compositional method to link multiple movements by using recurring musical themes will be examined. Secondly, the treatment of biblical and non-biblical texts will be studied. Therefore, Hodie will be seen to represent a synthesis of compositional techniques based on the unique individuality of the musical style of Vaughan Williams. This project is divided into four chapters, \u27Hodie: An Overview of the Work,\u27 \u27The Relationships of Biblical Narratives and Poetic Insertions,\u27 \u27Recurring Themes in Narrations and Other Movements,\u27 and \u27Hodie, Dona Nobis Pacem, and Sancta Civitas: A Comparison of Stylistic Change.\u27 Various tables and musical examples in chapters are used to compare poetry and themes as well as musical ideas
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