Hospital implementation of health information technology and quality of care: are they related?

Recently, there has been considerable effort to promote the use of health information technology (HIT) in order to improve health care quality. However, relatively little is known about the extent to which HIT implementation is associated with hospital patient care quality. We undertook this study to determine the association of various HITs with: hospital quality improvement (QI) practices and strategies; adherence to process of care measures; risk-adjusted inpatient mortality; patient satisfaction; and assessment of patient care quality by hospital quality managers and front-line clinicians.This work was supported by a grant from the Commonwealth Fund. We are indebted to Anthony Shih and Anne-Marie Audet of the Fund for their advice, support, and constructive suggestions throughout the design and conduct of the study. We thank our colleagues - Raymond Kang, Peter Kralovec, Sally Holmes, Frances Margolin, and Deborah Bohr - for their valuable contributions to the development of the QAS, the CPS, and the database on which the analytic findings reported here were based. We also thank 3 M (TM) Health Information Systems' for use of its All Patient Refined Diagnosis Related Groups (APR-DRGs) software. We especially wish to thank Jennifer Drake for her contributions not only to survey development, but also to earlier analysis of survey findings relevant to this paper. (Commonwealth Fund)Published versio

Experimental measurement of particle size effects on the self-heating ignition of biomass piles: Homogeneous samples of dust and pellets

Biomass can become an important fuel source for future power generation worldwide. However biomass piles are prone to self-heating and can lead to fire. When storing and transporting biomass, it is usually in the form of pellets which vary in diameter but are on average in the order of 7 mm. However, pellets tend to break up into smaller particles and into dust down to the µm size. For self-heating, size of particles is known to matter but the topic is poorly studied for biomass piles. This work presents an experimental study on the self-heating ignition behaviour of different particle sizes of wheat biomass. We study for the first time homogeneous samples from the dust scale to pellet diameter size, ranging from diameters of 300 µm to 6.5 mm. Experiments are done in an isothermal oven to find minimum ignition temperatures as a function of sample volume. The results are analysed using Frank-Kamenetskii theory. For the homogeneous biomass samples studied, we show that particle diameter variation does not bring a large change in self-heating ignition behaviour. The present work can be used to help quantify size effects on biomass ignition and help address the safety problems of biomass fires

Metallic Nanoparticles Generation by Repetitive Pulsed Laser for Applications in Bio-Medicine

A Nd:YAG pulsed laser operating at the 1064 nm wavelength, the 3 ns pulse duration, the 1010 W/cm2 intensity and the 10 Hz repetition rate is employed to irradiate biocompatible metallic targets based on Au, Bi and Ag placed in water. The laser-matter interaction produces nanometric spherical particles. The concentration of the solution with nanoparticles is controllable by the laser parameters, the ablative emission process, the irradiation time and the water’s volume. Generally, nanoparticles of about 10 nm in size and concentrations of the order (0.1 ÷ 10) mg/ml are prepared to be injected in cell cultures or in living systems (mice). The nanoparticles introduction in the extra and intra cellular liquids improves the bio-imaging of the tissue and organs by using fluorescence techniques. Moreover, if these nanoparticles are concentrated in tumour cells, they make possible high efficiency radio-therapy and thermal-therapy treatments, as it will be presented and discussed

A transferable prediction model of molecular adsorption on metals based on adsorbate and substrate properties

Surface adsorption is one of the fundamental processes in numerous fields, including catalysis, the environment, energy and medicine. The development of an adsorption model which provides an effective prediction of binding energy in minutes has been a long term goal in surface and interface science. The solution has been elusive as identifying the intrinsic determinants of the adsorption energy for various compositions, structures and environments is non-trivial. We introduce a new and flexible model for predicting adsorption energies to metal substrates. The model is based on easily computed, intrinsic properties of the substrate and adsorbate, which are the same for all the considered systems. It is parameterised using machine learning based on first-principles calculations of probe molecules (e.g., H2O, CO2, O2, N2) adsorbed to a range of pure metal substrates. The model predicts the computed dissociative adsorption energy to metal surfaces with a correlation coefficient of 0.93 and a mean absolute error of 0.77 eV for the large database of molecular adsorption energies provided by Catalysis-Hub.org which have a range of 15 eV. As the model is based on pre-computed quantities it provides near-instantaneous estimates of adsorption energies and it is sufficiently accurate to eliminate around 90% of candidates in screening study of new adsorbates. The model, therefore, significantly enhances current efforts to identify new molecular coatings in many applied research fields

The quantum algebra of superspace

We present the complete set of $N=1$, $D=4$ quantum algebras associated to massive superparticles. We obtain the explicit solution of these algebras realized in terms of unconstrained operators acting on the Hilbert space of superfields. These solutions are expressed using the chiral, anti-chiral and tensorial projectors which define the three irreducible representations of the supersymmetry on the superfields. In each case the space-time variables are non-commuting and their commutators are proportional to the internal angular momentum of the representation. The quantum algebra associated to the chiral or the anti-chiral projector is the one obtained by the quantization of the Casalbuoni-Brink-Schwarz (superspin 0) massive superparticle. We present a new superparticle action for the (superspin 1/2) case and show that their wave functions are the ones associated to the irreducible tensor multiplet.Comment: 20 pages;changes in the nomenclatur

Interaction of Water and Oxygen Molecules with Phosphorene: An Ab Initio Study

Phosphorene, the 2D form of black phosphorus, has recently attracted interest for optoelectronic and tribological applications. However, its promising properties are affected by the strong tendency of the layers to oxidize in ambient conditions. A significant effort has been made to identify the role of oxygen and water in the oxidation process. In this work, we introduce a first-principles study of the phosphorene phase diagram and provide a quantitative estimate of the interaction of pristine and fully oxidized phosphorene layers with oxygen and water molecules. Specifically, we study oxidized layers with oxygen coverages of 25% and 50% that keep the typical anisotropic structure of the layers. We found that hydroxilated and hydrogenated phosphorene layers are both energetically unfavorable, leading to structural distortions. We also studied the water physisorption on both pristine and oxidized layers, finding that the adsorption energy gain doubled on the oxidized layers, whereas dissociative chemisorption was always energetically unfavorable. At the same time, further oxidation (i.e., the dissociative chemisorption of O (Formula presented.)) was always favorable, even on oxidized layers. Ab initio molecular dynamics simulations of water intercalated between sliding phosphorene layers showed that even under harsh tribological conditions water dissociation was not activated, thus further strengthening the results obtained from our static calculations. Overall, our results provide a quantitative description of the interaction of phosphorene with chemical species that are commonly found in ambient conditions at different concentrations. The phase diagram that we introduced confirms the tendency of phosphorene layers to fully oxidize due to the presence of O (Formula presented.), resulting in a material with improved hydrophilicity, a piece of information that is relevant for the application of phosphorene, e.g., as a solid lubricant. At the same time, the structural deformations found for the H- and OH- terminated layers undermine their electrical, mechanical, and tribological anisotropic properties and, therefore, the usage of phosphorene

Laser-generated plasmas by graphene nanoplatelets embedded into polyethylene

AbstractGraphene micrometric particles have been embedded into polyethylene at different concentrations by using chemical–physical processes. The synthesized material was characterized in terms of mechanical and optical properties, and Raman spectroscopy. Obtained targets were irradiated by using a Nd:YAG laser at intensities of the order of 1010 W/cm2 to generate non-equilibrium plasma expanding in vacuum. The laser–matter interaction produces charge separation effects with consequent acceleration of protons and carbon ions. Plasma was characterized using time-of-flight measurements of the accelerated ions. Applications of the produced targets in order to generate carbon and proton ion beams from laser-generated plasma are presented and discussed

On Non Commutative G2 structure

Using an algebraic orbifold method, we present non-commutative aspects of $G_2$ structure of seven dimensional real manifolds. We first develop and solve the non commutativity parameter constraint equations defining $G_2$ manifold algebras. We show that there are eight possible solutions for this extended structure, one of which corresponds to the commutative case. Then we obtain a matrix representation solving such algebras using combinatorial arguments. An application to matrix model of M-theory is discussed.Comment: 16 pages, Latex. Typos corrected, minor changes. Version to appear in J. Phys.A: Math.Gen.(2005

On The spectrum of a Noncommutative Formulation of the D=11 Supermembrane with Winding

A regularized model of the double compactified D=11 supermembrane with nontrivial winding in terms of SU(N) valued maps is obtained. The condition of nontrivial winding is described in terms of a nontrivial line bundle introduced in the formulation of the compactified supermembrane. The multivalued geometrical objects of the model related to the nontrivial wrapping are described in terms of a SU(N) geometrical object which in the $N\to \infty$ limit, converges to the symplectic connection related to the area preserving diffeomorphisms of the recently obtained non-commutative description of the compactified D=11 supermembrane.(I. Martin, J.Ovalle, A. Restuccia. 2000,2001) The SU(N) regularized canonical lagrangian is explicitly obtained. In the $N\to \infty$ limit it converges to the lagrangian in (I.Martin, J.Ovalle, A.Restuccia. 2000,2001) subject to the nontrivial winding condition. The spectrum of the hamiltonian of the double compactified D=11 supermembrane is discussed. Generically, it contains local string like spikes with zero energy. However the sector of the theory corresponding to a principle bundle characterized by the winding number $n \neq 0$, described by the SU(N) model we propose, is shown to have no local string-like spikes and hence the spectrum of this sector should be discrete.Comment: 16 pages.Latex2