A Systematic Survey of the Effects of Wind Mass Loss Algorithms on the Evolution of Single Massive Stars

Mass loss is a key uncertainty in the evolution of massive stars. Stellar evolution calculations must employ parametric algorithms for mass loss, and usually only include stellar winds. We carry out a parameter study of the effects of wind mass loss on massive star evolution using the open-source stellar evolution code MESA. We provide a systematic comparison of wind mass loss algorithms for solar-metallicity, nonrotating, single stars in the initial mass range of $15-35\,M_\odot$. We consider combinations drawn from two hot phase algorithms, three cool phase algorithms, and two Wolf-Rayet algorithms. We consider linear wind efficiency scale factors of $1$, $0.33$, and $0.1$ to account for reductions in mass loss rates due to wind inhomogeneities. We find that the initial to final mass mapping for each zero-age main-sequence (ZAMS) mass has a $\sim 50\%$ uncertainty if all algorithm combinations and wind efficiencies are considered. The ad-hoc efficiency scale factor dominates this uncertainty. While the final total mass and internal structure of our models vary tremendously with mass loss treatment, final observable parameters are much less sensitive for ZAMS mass $\lesssim 30\,M_\odot$. This indicates that uncertainty in wind mass loss does not negatively affect estimates of the ZAMS mass of most single-star supernova progenitors from pre-explosion observations. Furthermore, we show that the internal structure of presupernova stars is sensitive to variations in both main sequence and post main-sequence mass loss. We find that the compactness parameter $\xi\propto M/R(M)$ varies by as much as $30\%$ for a given ZAMS mass evolved with different wind efficiencies and mass loss algorithm combinations. [abridged]Comment: Accepted for publication on A&A, 22 pages + 2 appendixes, 12 figures, online input parameters available at https://stellarcollapse.org/renzo2017 and data at https://zenodo.org/record/292924#.WK0q2tWi6W

Spatial multiplexing in near field MIMO channels with reconfigurable intelligent surfaces

We consider a multiple-input multiple-output (MIMO) channel in the presence of a reconfigurable intelligent surface (RIS). Specifically, our focus is on analysing the spatial multiplexing gains in line-of-sight and low-scattering MIMO channels in the near field. We prove that the channel capacity is achieved by diagonalising the end-to-end transmitter-RIS-receiver channel, and applying the water-filling power allocation to the ordered product of the singular values of the transmitter-RIS and RIS-receiver channels. The obtained capacity-achieving solution requires an RIS with a non-diagonal matrix of reflection coefficients. Under the assumption of nearly-passive RIS, that is, no power amplification is needed at the RIS, the water-filling power allocation is necessary only at the transmitter. We refer to this design of RIS as a linear, nearly-passive, reconfigurable electromagnetic object (EMO). In addition, we introduce a closed-form and low-complexity design for RIS, whose matrix of reflection coefficients is diagonal with unit-modulus entries. The reflection coefficients are given by the product of two focusing functions: one steering the RIS-aided signal towards the mid-point of the MIMO transmitter and one steering the RIS-aided signal towards the mid-point of the MIMO receiver. We prove that this solution is exact in line-of-sight channels under the paraxial setup. With the aid of extensive numerical simulations in line-of-sight (free-space) channels, we show that the proposed approach offers performance (rate and degrees of freedom) close to that obtained by numerically solving non-convex optimization problems at a high computational complexity. Also, we show that it provides performance close to that achieved by the EMO (non-diagonal RIS) in most of the considered case studies

apeNEXT: A multi-TFlops Computer for Simulations in Lattice Gauge Theory

We present the APE (Array Processor Experiment) project for the development of dedicated parallel computers for numerical simulations in lattice gauge theories. While APEmille is a production machine in today's physics simulations at various sites in Europe, a new machine, apeNEXT, is currently being developed to provide multi-Tflops computing performance. Like previous APE machines, the new supercomputer is largely custom designed and specifically optimized for simulations of Lattice QCD.Comment: Poster at the XXIII Physics in Collisions Conference (PIC03), Zeuthen, Germany, June 2003, 3 pages, Latex. PSN FRAP15. Replaced for adding forgotten autho

Perturbative expansions from Monte Carlo simulations at weak coupling: Wilson loops and the static-quark self-energy

Perturbative coefficients for Wilson loops and the static-quark self-energy are extracted from Monte Carlo simulations at weak coupling. The lattice volumes and couplings are chosen to ensure that the lattice momenta are all perturbative. Twisted boundary conditions are used to eliminate the effects of lattice zero modes and to suppress nonperturbative finite-volume effects due to Z(3) phases. Simulations of the Wilson gluon action are done with both periodic and twisted boundary conditions, and over a wide range of lattice volumes (from $3^4$ to $16^4$) and couplings (from $\beta \approx 9$ to $\beta \approx 60$). A high precision comparison is made between the simulation data and results from finite-volume lattice perturbation theory. The Monte Carlo results are shown to be in excellent agreement with perturbation theory through second order. New results for third-order coefficients for a number of Wilson loops and the static-quark self-energy are reported.Comment: 36 pages, 15 figures, REVTEX documen

Body composition changes and cardiometabolic benefits of a balanced Italian Mediterranean Diet in obese patients with metabolic syndrome

Metabolic syndrome (MS) is a cluster of metabolic alteration associated with a higher risk of cardiovascular disease and overall mortality than the single alterations alone. The Italian Mediterranean Diet (IMD) can exert a positive effect on cardiovascular risk and related morbidity and mortality. The aim was to evaluate the benefits of dietary intervention based on a typical IMD on body composition, cardiometabolic changes and reduction in cardiovascular disease in patients with MS. Eighty White Italian subjects with MS were prescribed a balanced hypocaloric IMD. We investigated dietary habits and impact of the diet on health status, blood biochemical markers, anthropometric measurements and body composition during a 6-month follow-up period. Body composition, fat mass and distribution were assessed by Dual X-ray absorptiometry. Adherence to the IMD led to a decrease in body weight (102.59 ± 16.82 to 92.39 ± 15.94 kg, p < 0.001), body mass index (BMI) (38.57 ± 6.94 to 35.10 ± 6.76, <0.001) and waist circumference (112.23 ± 12.55 vs 92.42 ± 18.17 cm, p < 0.001). A significant loss of total body fat especially in waist region was observed. The MS was resolved in 52 % of the patients. Significant improvements in systolic and diastolic blood pressure and fasting glucose occurred. Low-density lipoprotein cholesterol was reduced from 128.74 ± 33.18 to 108.76 ± 38.61 mg/dl (p < 0.001), triglycerides from 169.81 ± 80.80 to 131.02 ± 63.88 mg/dl (p < 0.001). The present results suggest that a dietary intervention based on a typical IMD effectively promotes weight loss and reduces the growing burden of cardiovascular risk factors that typifies patients with MS

Efficacy of two different ProMACE-CytaBOM derived regimens in advanced aggressive non-Hodgkin's lymphoma. Final report of a multicenter trial conducted by GISL

Background and Objective. To compare the efficacy of ProME(Epidoxorubicin)CE-CytaBOM (PE-C) and ProMI(Idarubicin)CE-CytaBOM (PIG) in the treatment of adult patients with aggressive non Hodgkin's lymphoma in a multicenter randomized controlled trial performed by 18 centers of the Italian Lymphoma Study Group (GISL). Design and Methods. One hundred and twenty-eight and 122 patients were randomly assigned to receive either 6 courses of PE-C or PI-C, respectively. Some patients achieving complete remission with induction therapy participated in another randomized study comparing no further therapy versus maintenance therapy consisting of four blocks of two drugs. Results. The rate of CRs was 62% and 64% for patients treated with PE-C and PI-C, respectively (p=0.51). The 5-year relapse-free survival was 60% for PE-C and 53% for PI-C (p=0.29). The estimated relapse-free disease survival rates at 4 years were 75% for patients in the consolidation group and 57% for those in the observation group (p=0.11). Patients alive In first complete remission 4 years after study entry were estimated to be 39% in the PE-C arm and 38% in the PI-C arm (p=0.90). The 3-year and 5-year estimated survival rates were 61% and 55% for the PE-C group and 56% and 47% for the PI-C group (p=0.26). Fatal toxicities occurred in 7 patients (2.9%) with active disease and in 4 patients (1.7%) in complete remission. Stage (p=0.04), bulky disease (p=0.02), serum LDH (p=0.0006), serum albumin (p=0.0051), hemoglobin (p=0.0011), performance status (p=0.0001), International prognostic index (p<0.0001) and the index proposed by the French group G.E.L.A. (p<0.0001) were of prognostic value. In a multivariate analysis (Cox regression model) alternatively IPI alone or G.E.L.A, index plus performance status emerged as independent prognostic factors. Interpretation and Conclusions. The present study indicates that epirubicin and idarubicin in a combined chemotherapy regimen, have similar activities. The toxic profile also indicates the safety of both anthracyclines at the dosages employed, suggesting their possible dose escalation in a combined chemotherapy setting. PE-C and PI-C were both effective and feasible regimens in an outpatient setting, with acceptable cardiovascular toxicity. The trend toward a better outcome in patients undergoing consolidation therapy after the achievement of a complete remission, warrants further investigation. (C)1998, Ferrata Storti Foundation

The role of MTHFR polymorphisms in the risk of lipedema

Objective: This study examines the role of MTHFR gene polymorphism (rs1801133) in women with lipedema (LIPPY) body composition parameters compared to a control group (CTRL). Subjects and methods: We carried out a study on a sample of 45 LIPPY and 50 women as a CTRL. Body composition parameters were examined by Dual-energy X-ray Absorptiometry (DXA). A genetic test was performed for the MTHFR polymorphism (rs1801133, 677C&gt;T) using a saliva sample for LIPPY and CTRL groups. Mann-Whitney tests evaluated statistically significant differences between four groups (carriers and non-carriers of the MTHFR polymorphism for LIPPY and CTRL groups) on anthropometric/body composition parameters to identify patterns. Results: LIPPY showed significantly higher (p&lt;0.05) anthropometric parameters (weight, BMI, waist, abdominal, hip circumferences) and lower waist/hip ratio (p&lt;0.05) compared to the CTRL group. The association between the polymorphism alleles related to the rs1801133 MTHFR gene and the body composition values LIPPY carriers (+) showed an increase in fat tissue of legs and fat region of legs percentage, arm's fat mass (g), leg's fat mass (g), and leg's lean mass (g) (p&lt;0.05) compared to CTRL (+). Lean/fat arms and lean/fat legs were lower (p&lt;0.05) in LIPPY (+) than in CTRL (+). In the LIPPY (+), the risk of developing the lipedema disease was 2.85 times higher (OR=2.85; p&lt;0.05; 95% confidence interval = 0.842-8.625) with respect to LIPPY (-) and CTRL. Conclusions: The presence or absence of MTHFR polymorphism offers predictive parameters that could better characterize women with lipedema based on the association between body composition and MTHFR presence

Design of Multicationic Copper-Bearing Layered Double Hydroxides for Catalytic Application in Biorefinery

Ethanol has been used as a renewable hydrogen-donor in the conversion of a lignin model molecule in subcritical conditions. Noble metal-free porous mixed oxides, obtained by activation of Cu-Ni-Al and Cu-Ni-Fe layered double hydroxide (LDH) precursors, have been used as heterogeneous catalysts for Meerwein-Ponndorf-Verley (MPV) hydrogen transfer and further hydrogenation by ethanol dehydrogenation products. Both the Cu/(Cu+Ni) ratio and the nature of the trivalent cation (Al or Fe) affect the activity of the catalysts, as well as the selectivity towards the different steps of the hydrogenation reactions and the cleavage of lignin-like phenylether bonds. Accounting for the peculiar behaviour of Cu2+ and M(III) cations in the synthesis of LDHs, the coprecipitation of the precursors has been monitored by titration experiments. Structural and textural properties of the catalysts are closely related to the composition of the LDH precursors