511 research outputs found
A Dynamical Reliability Prediction Algorithm for Composite Service
Dynamic selection and dynamic binding and rebinding at runtime are new characters of composite services. The traditional static reliability prediction models are unsuitable to dynamic composite services. A new reliability predicting algorithm for composite services is proposed in this paper. Firstly, a composite service is decomposed into composition unites (executing path, composite module and atomic service) according to their constituents. Consequently, a hierarchical graph of all composite units is constructed. Lastly, a new dynamic reliability prediction algorithm is presented. Comparing with the traditional reliability model, the new dynamic reliability approach is more flexible, which does not recompute reliability for all composite units and only computes the reliability of the effected composite units. In addition, an example to show how to measure the reliability based on our algorithm is designed. The experimental results show our proposed methods can give an accurate estimation of reliability. Furthermore, a more flexible sensitivity analysis is performed to determine which service component has the most significant impact on the improvement of composite service reliability
A new classification system of lithic-rich tight sandstone and its application to diagnosis high-quality reservoirs
Lithic-rich tight sandstone is one of the most enrichment lithofacies in the Sulige gas field. Clarifying the enrichment mechanism of high-quality lithic-rich tight sandstone is important to economic and efficient development of the tight gas reservoir. This paper introduces a new classification method, which is based on the origin of particles and interstitial materials and their control on reservoir pores growth. Lithic-rich tight sandstone can be subdivided into three types: sedimentary lithic sandstone, diagenetic lithic sandstone and event-type lithic sandstone. The genetic mechanism of a high-quality reservoir is studied by this new method. Research shows that the sedimentary lithic sandstone has high contents of plastic lithics, strong compaction effects of early diagenesis, large porosity reduction and almost no dissolution-induced porosity. The diagenetic lithic sandstone has high contents of rigid lithics and strong compaction effects. Organic acids promote alteration of a large amount of feldspars into kaolinite, while such sandstones are highly cemented. It is seen with moderate porosity reduction and moderate dissolution-attributed porosity growth. Event-type lithic sandstone also has high contents of rigid debris and strong compaction effects. Synsedimentary volcanic dust materials of subaerial deposition are altered into illite through smectite and illite-smectite mixed-layer clay under the effects of acids, which generate many pores and results in large dissolution-attributed porosity growth. Research shows that the sedimentary lithic sandstone has poor physical properties and is identified as the unfavorable reservoir; the diagenetic lithic sandstone having medium physical properties, as the relatively favorable reservoir; the event-type lithic sandstone having good physical properties, as the favorable reservoir. The research route and results have laid a solid geological foundation for better development of lithic-rich tight sandstone reservoirs.Cited as: Liu, Y., Xian, C., Li, Z., Wang, J., Ren, F. A new classification system of lithic-rich tight sandstone and its application to diagnosis high-quality reservoirs. Advances in Geo-Energy Research, 2020, 4(3): 286-295, doi: 10.46690/ager.2020.03.0
Natural anti-phytopathogenic fungi compound phenol, 2, 4-bis (1, 1-dimethylethyl) from Pseudomonas fluorescens TL-1
A strain was isolated from tobacco phylloplane and preliminarily identified as Pseudomonas fluorescens TL-1, which had the visible inhibition against ten plant pathogenic fungi, viz., Curvularia lunata, Bipolaris maydis, Valsa mali, Rhizoctonia solani, Colletotrichum gloeosporioides, Sclerotinia sclerotiorum, Botrytis cinerea, Alternaria alternate, Fusarium oxysporum and Verticillium dahlia in dual culture experiments. The ethyl acetate extract of nutrient broth seeded with Pseudomonas fluorescens TL-1 suspension was separated into fifty-nine fractions by the Sephadex LH-20 column and the antifungal activity of each fraction was tested with paper disc diffusion method against Curvularia lunata. The results showed that fraction 1 to 3 had the strongest inhibitory effects on Curvularia lunata. Furthermore, GC/MS analysis of the constituents of fraction 1 to 59 confirmed that phenol, 2, 4-bis (1, 1-dimethylethyl) was the active compound for the antifungal activity from Pseudomonas fluorescens TL-1
Optimal Control of a Delay-Varying Computer Virus Propagation Model
By incorporating the objective of keeping a low number of infected nodes and a high number of recovered nodes at a lower cost into a known computer virus model (the delay-varying SIRC model) extended by introducing quarantine, a novel model is described by means of the optimal control strategy and theoretically analyzed. Through the comparison of simulation results, it is shown that the propagation of computer virus with varying latency period can be suppressed effectively by the optimal control strategy
Early fault diagnosis method for gearbox based on second-order underdamped SR and its application
Stochastic resonance (SR) has been proved to be an effective method to extract weak-fault signals from gearboxes under strong noise. In this paper, we propose a method based on underdamped second-order SR with a new potential function. In our testing, we added an appropriate amount of Gaussian white noise to the original signal. When it matched the periodic signal and the potential function, the method showed good noise reduction ability, highlighted the fault signal and extracted fault information more effectively than the traditional SR method. The ant colony algorithm was used to optimize the potential parameters of the SR potential model and obtain the best output signal-to-noise ratio (SNR). We verified the proposed method by computer simulation and experimental verification, demonstrating that it produced better output than that of the traditional SR method
Intrinsic Piezoelectric Anisotropy of Tetragonal ABO3 Perovskites: A High-Throughput Study
A comprehensive understand of the intrinsic piezoelectric anisotropy stemming
from diverse chemical and physical factors is a key step for the rational
design of highly anisotropic materials. We performed high-throughput
calculations on tetragonal ABO3 perovskites to investigate the piezoelectricity
and the interplay between lattice, displacement, polarization and elasticity.
Among the 123 types of perovskites, the structural tetragonality is naturally
divided into two categories: normal tetragonal (c/a ratio < 1.1) and
super-tetragonal (c/a ratio > 1.17), exhibiting distinct ferroelectric,
elastic, and piezoelectric properties. Charge analysis revealed the mechanisms
underlying polarization saturation and piezoelectricity suppression in the
super-tetragonal region, which also produces an inherent contradiction between
high d33 and large piezoelectric anisotropy ratio |d33/d31|. The polarization
axis and elastic softness direction jointly determine the maximum longitudinal
piezoelectric response d33 direction. The validity and deficiencies of the
widely utilized |d33/d31| ratio for representing piezoelectric anisotropy were
reevaluated
2-[2-(2-Carboxyphenyl)hydrazinylidene]-3-oxo-N-phenylbutyramide
In the title compound, C17H15N3O4, the molecule is in the keto–hydrazone form. Intramolecular N—H⋯O hydrogen bonds ensure that the molecule is nearly planar (r.m.s. deviation of non-H atoms is 0.098 Å), with the two benzene rings forming a dihedral angle of 10.04 (2)°. In the crystal, inversion dimers are formed via pairs of O—H⋯O hydrogen bonds involving the –CO2H groups
N-(4-hydroxyphenyl) retinamide inhibits migration of renal carcinoma cells and promotes autophagy via MAPK p38 pathway
Purpose: To investigate the effect of N-(4-hydroxyphenyl) retinamide (4HPR) on autophagy and migration of renal carcinoma cells.Methods: Renal cancer cell lines were treated with various concentrations of 4HPR. Proliferation of the cells was studied using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltrazolium bromide (MTT), while apoptosis and cell cycle arrest were determined by flow cytometry.Results: Treatment of RCCs with 30 μM 4HPR caused significant inhibition of viability. In 786-O and OS-RC-2 cell lines, 4HPR reduced colony formation by 39 and 43 %, respectively. In addition, 4HPR increased the percentage of 786-O cells in G1 phase from 58.79 ± 3.43 to 71.68 ± 4.47 % (p < 0.05). It also decreased the percentage of cells in the S-phase from 21.98 ± 2.78 to 09.17 ± 1.43 %, and enhanced the activation of p38 and JNK in 786-O cells at 48 h. Western blot assay showed that the activation of p38 and JNK by 4HPR was inhibited on pre-treatment with SB203580 (inhibitor of p38) and SP600125 (inhibitor of JNK), respectively. Reduction of 786-O cell viability by 4HPR treatment was also significantly inhibited by pre-treatment with sp203580 and sp600125 (p < 0.05). Furthermore, the inhibitors also reversed the effect of 4HPR on the expressions of Bax and Bcl-2 in 786-O cells.Conclusion: These results indicate that 4HPR inhibits the growth of renal cancer cells via activation of MAPK signalling pathway. Thus, 4HPR is a potential drug target for management of renal cancer.Keywords: Retinamide, Renal cancer, Autophagy, MAPK signalling, Cell proliferation, N-terminal kinas
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