5 research outputs found

    A comparative study of material hardening models for forming operations and prediction of kinematic hardening by means of an analytical indicator

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    This publication is focused on comparing three different material hardening models i.e. purely isotropic, mixed hardening and purely kinematic hardening model for the simulation of forming operations. The influence of nonlinear strain paths is investigated using deep drawing and strip tensile bending experiments and their comparison with numerical simulations. This comparison enables us to determine which of the three material models is more accurate for forming operations. Subsequently, the complex nonlinear strain paths are analyzed using an analytical indicator developed at the Chair of Forming and Machining Process, TU Dresden [3], to predict the influence of kinematic hardening by comparing the experimental results with a combined material hardening model as well as a purely isotropic and kinematic material model. The analytical indicator illustrates the regions in deformed samples that are most affected by kinematic hardening and shows the difference in target values as a result of mixed and purely isotropic hardening la

    Acoustical modeling and Bayesian inference for rigid porous media in the low-mid frequency regime

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    International audienceIn this article, a modeling extension for the description of wave propagation in porous media at low-mid frequencies is introduced. To better characterize the viscous and inertial interactions between the fluid and the structure in this regime, two additional terms described by two parameters α1 and α2 are taken into account in the representation of the dynamic tortuosity in a Laurent-series on frequency. The model limitations are discussed. A sensitivity analysis is performed, showing that the influence of α1 and α2 on the acoustic response of porous media is significant. A general Bayesian inference is then conducted to infer, simultaneously, the posterior probability densities of the model parameters. The proposed method is based on the measurement of waves transmitted by a slab of rigid porous material, using a temporal model for the direct and inverse transmission problem. Bayesian inference results obtained on three different porous materials are presented, which suggests that the two additional parameters are accessible and help reduce systematic errors in the identification of other parameters: porosity, static viscous permeability, static viscous tortuosity, static thermal permeability, and static thermal tortuosity

    Monitoring the evolution of dimensional accuracy and product properties in property-controlled forming processes

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    As recent trends in manufacturing engineering disciplines show a clear development in the sustainable as well as economically efficient design of forming processes, monitoring techniques have been gaining in relevance. In terms of monitoring of product properties, most processes are currently open-loop controlled, entailing that the microstructure evolution, which determines the final product properties, is not considered. However, a closed-loop control that can adjust and manipulate the process actuators according to the required product properties of the component will lead to a considerable increase in efficiency of the processes regarding resources and will decrease postproduction of the component. For most forming processes, one set of component dimensions will result in a certain set of product properties. However, to successfully establish closed-loop property controls for the processes, a systematic understanding of the reciprocity of the dimensions after forming and final product properties must be established. This work investigates the evolution of dimensional accuracy as well as product properties for a series of forming processes that utilize different degrees of freedom for process control

    High Risk of Anal and Rectal Cancer in Patients With Anal and/or Perianal Crohn’s Disease

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    International audienceBackground & AimsLittle is known about the magnitude of the risk of anal and rectal cancer in patients with anal and/or perineal Crohn’s disease. We aimed to assess the risk of anal and rectal cancer in patients with Crohn’s perianal disease followed up in the Cancers Et Surrisque AssociĂ© aux Maladies Inflammatoires Intestinales En France (CESAME) cohort.MethodsWe collected data from 19,486 patients with inflammatory bowel disease (IBD) enrolled in the observational CESAME study in France, from May 2004 through June 2005; 14.9% of participants had past or current anal and/or perianal Crohn’s disease. Subjects were followed up for a median time of 35 months (interquartile range, 29–40 mo). To identify risk factors for anal cancer in the total CESAME population, we performed a case-control study in which participants were matched for age and sex.ResultsAmong the total IBD population, 8 patients developed anal cancer and 14 patients developed rectal cancer. In the subgroup of 2911 patients with past or current anal and/or perianal Crohn’s lesions at cohort entry, 2 developed anal squamous-cell carcinoma, 3 developed perianal fistula–related adenocarcinoma, and 6 developed rectal cancer. The corresponding incidence rates were 0.26 per 1000 patient-years for anal squamous-cell carcinoma, 0.38 per 1000 patient-years for perianal fistula–related adenocarcinoma, and 0.77 per 1000 patient-years for rectal cancer. Among the 16,575 patients with ulcerative colitis or Crohn’s disease without anal or perianal lesions, the incidence rate of anal cancer was 0.08 per 1000 patient-years and of rectal cancer was 0.21 per 1000 patient-years. Among factors tested by univariate conditional regression (IBD subtype, disease duration, exposure to immune-suppressive therapy, presence of past or current anal and/or perianal lesions), the presence of past or current anal and/or perianal lesions at cohort entry was the only factor significantly associated with development of anal cancer (odds ratio, 11.2; 95% CI, 1.18-551.51; P = .03).ConclusionsIn an analysis of data from the CESAME cohort in France, patients with anal and/or perianal Crohn’s disease have a high risk of anal cancer, including perianal fistula–related cancer, and a high risk of rectal cancer
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