907 research outputs found

    (Un)anticipated Technological Change in an Endogenous Growth Model

    Get PDF
    This paper examines numerically the impact of a negative exogenous shock to marginal productivity (such as ecological government regulation that becomes effective at some point in time) in an endogenous finite-time growth model with sluggish reallocation of human capital. The policy can be anticipated or unanticipated by firms, and it can also be announced but not implemented. It turns out that these frictions have a very strong long-run effect on output, consumption and on the optimal allocation of capital and labor in particular. The qualitative properties relate to homogenous labor models with positive productivity shocks. The problem is thus to maximize a function of a continuous system, where the system is subject to frictions and stepwise changes; for such a problem the application of calculus of variations necessary conditions is problematic. A numerical optimization method, which has had much success on qualitatively similar problems in engineering, has been employed.two-sector endogenous growth model; unanticipated and anticipated technological change; frictions in reallocation of human capital; Runge-Kutta parallel shooting algorithm

    Lower algebraic K-theory of certain reflection groups

    Full text link
    For a finite volume geodesic polyhedron P in hyperbolic 3-space, with the property that all interior angles between incident faces are integral submultiples of Pi, there is a naturally associated Coxeter group generated by reflections in the faces. Furthermore, this Coxeter group is a lattice inside the isometry group of hyperbolic 3-space, with fundamental domain the original polyhedron P. In this paper, we provide a procedure for computing the lower algebraic K-theory of the integral group ring of such Coxeter lattices in terms of the geometry of the polyhedron P. As an ingredient in the computation, we explicitly calculate some of the lower K-groups of the dihedral groups and the product of dihedral groups with the cyclic group of order two.Comment: 35 pages, 2 figure

    Neurochemical compartmentalization within the pigeon basal ganglia

    Get PDF
    The goals of this study were to use multiple informative markers to define and characterize the neurochemically distinct compartments of the pigeon basal ganglia, especially striatum and accumbens. To this end, we used antibodies against 12 different neuropeptides, calcium-binding proteins or neurotransmitter-related enzymes that are enriched in the basal ganglia. Our results clarify boundaries between previously described basal ganglia subdivisions in birds, and reveal considerable novel heterogeneity within these previously described subdivisions. Sixteen regions were identified that each displayed a unique neurochemical organization. Four compartments were identified within the dorsal striatal region. The neurochemical characteristics support previous comparisons to part of the central extended amygdala, somatomotor striatum, and associational striatum of mammals, respectively. The medialmost part of the medial striatum, however, has several unique features, including prominent pallidal-like woolly fibers and thus may be a region unique to birds. Four neurochemically distinct regions were identified within the pigeon ventral striatum: the accumbens, paratubercular striatum, ventrocaudal striatum, and the ventral area of the lateral part of the medial striatum that is located adjacent to these regions. The pigeon accumbens is neurochemically similar to the mammalian rostral accumbens. The pigeon paratubercular and ventrocaudal striatal regions are similar to the mammalian accumbens shell. The ventral portions of the medial and lateral parts of the medial striatum, which are located adjacent to accumbens shell-like areas, have neurochemical characteristics as well as previously reported limbic connections that are comparable to the accumbens core. Comparisons to neurochemically identified compartments in reptiles, mammals, and amphibians indicate that, although most of the basic compartments of the basal ganglia were highly conserved during tetrapod evolution, uniquely avian compartments may exist as well

    Intellectual Property in Medical Imaging and Informatics: The Independent Inventor’s Perspective

    Get PDF
    While innovation and new product development is traditionally thought of as the exclusive domain of industry and academia, a large number of innovations in medicine and information technology have come from independent inventors, which account for almost 30% of new patents issued in the U.S. today. A large number of economic, political, and legal challenges exist within the current marketplace that serves as relative impediments to independent invention. This article explores the existing challenges facing the independent inventor and offers a number of recommendations and resources to facilitate independent inventors in their quest for innovation and entrepreneurship. The concept of “outsourcing innovation” is discussed as an alternative to the existing model of industry sponsored research and development (R&D), with the goal of combining the unique attributes and strengths of independent inventors and industry sponsors

    The Challenges, Opportunities, and Imperative of Structured Reporting in Medical Imaging

    Get PDF
    Despite dramatic innovation in medical imaging and information system technologies, the radiology report has remained stagnant for more than a century. Structured reporting was created in the hopes of addressing well-documented deficiencies in report content and organization but has largely failed in its adoption due to concerns over workflow and productivity. A number of political, economical, and clinical quality-centric initiatives are currently taking place within medicine which will dramatically change the medical landscape including Pay for Performance, Evidence-Based Medicine, and the Physician Quality Reporting Initiative. These will collectively enhance efforts to improve quality in reporting, stimulate new technology development, and counteract the impending threat of commoditization within radiology. Structured reporting offers a number of unique opportunities and advantages over traditional free text reporting and will provide a means for the radiology community to add value to its most important service deliverable the radiology report

    The state of POPs in Ghana- A review on persistent organic pollutants: Environmental and human exposure

    Get PDF
    Ghana is one of the top pesticide users and highest persistent organic pollutant (POP) emitters in sub-saharan Africa. Despite recent increases in published data, there is limited information on how POP concentrations have changed, post ratification of the Stockholm Convention. As a result, this review aims to address these knowledge gaps by collating available data that reported POPs in Ghanaian environmental matrices, identify spatial and temporal trends, and establish potential health risks. It is worth noting that Ghana has not developed its own regulatory standards for POPs, but adapts United States Environmental Protection Agency (USEPA) standards. Results obtained showed concentrations in excess of USEPA regulatory standards for per- and poly-fluoroalkyl sulphonates (PFASs) and dichlorodiphenyldichloroethane (DDD) in water, polychlorinated and polybrominated dibenzo-p-dioxins and furans (PCDD/Fs and PBDD/Fs) in e-waste soils, and polybrominated diphenyl ethers in aquatic organisms and dairy products. The published studies do not cover major regions nationwide. The inconsistency in methods and analytes measured, along with data scarcity in some regions, makes it challenging to identify temporal trends. However, the data did indicate decreasing concentrations of some legacy POPs in soil/sediment and aquatic organisms, with increasing concentrations of some POPs in water, fish, fruits and vegetables. Studies that performed health risks assessments were limited although the data indicated risks to e-waste workers, some farmers and vulnerable sub-populations. This review identified potential human health risks from POPs in the Ghanaian environment and the need for more consistent and widespread monitoring program

    Setting the agenda: Climate change adaptation and mitigation for food systems in the developing world

    Get PDF
    New agricultural development pathways are required to meet climate change adaptation and mitigation needs in the food systems of low-income countries. A research and policy agenda is provided to indicate where innovation and new knowledge are needed. Adaptation requires identifying suitable crop varieties and livestock breeds, as well as building resilient farming and natural resources systems, institutions for famine and crop failure relief, and mechanisms for rapid learning by farmers. Mitigation requires transitioning to ‘low climate impact’ agriculture that reduces emissions while achieving food security, economic well-being and sustainability. Efficient interventions, incentives for large-scale shifts in practices, and monitoring systems are required. Integrated assessments of adaptation and mitigation are needed to better understand the synergies and trade-offs among outcomes

    Development and Evaluation of a Multi-Year Fractional Surface Water Data Set Derived from Active/Passive Microwave Remote Sensing Data

    Full text link
    The sensitivity of Earth’s wetlands to observed shifts in global precipitation and temperature patterns and their ability to produce large quantities of methane gas are key global change questions. We present a microwave satellite-based approach for mapping fractional surface water (FW) globally at 25-km resolution. The approach employs a land cover-supported, atmospherically-corrected dynamic mixture model applied to 20+ years (1992–2013) of combined, daily, passive/active microwave remote sensing data. The resulting product, known as Surface WAter Microwave Product Series (SWAMPS), shows strong microwave sensitivity to sub-grid scale open water and inundated wetlands comprising open plant canopies. SWAMPS’ FW compares favorably (R2 = 91%–94%) with higher-resolution, global-scale maps of open water from MODIS and SRTM-MOD44W. Correspondence of SWAMPS with open water and wetland products from satellite SAR in Alaska and the Amazon deteriorates when exposed wetlands or inundated forests captured by the SAR products were added to the open water fraction reflecting SWAMPS’ inability to detect water underneath the soil surface or beneath closed forest canopies. Except for a brief period of drying during the first 4 years of observation, the inundation extent for the global domain excluding the coast was largely stable. Regionally, inundation in North America is advancing while inundation is on the retreat in Tropical Africa and North Eurasia. SWAMPS provides a consistent and long-term global record of daily FW dynamics, with documented accuracies suitable for hydrologic assessment and global change-related investigations
    corecore