Using eCognition Definiens for automated detection of snow avalanche deposits from very high resolution optical imagery - New developments

The identification of snow avalanche deposits from high resolution optical satellite imagery had been the focus of the project "avalRS” which NGI, together with the Norwegian Computing Centre and Statens Veivesen, had carried out for the European Space Agency (2008-2011; e.g., Frauenfelder et al., 2011). The algorithms developed have produced variable results, often working well in certain situations and poorly in others. In 2011 using the object oriented image processing software eCognition, NGI developed two prototype algorithms on its own. The two algorithms were developed for (i) QuickBird satellite imagery, and (ii) Leica ADS-40 airborne imagery (cf. Lato and Frauenfelder, 2012).Aspart of the continuation of this research program, the algorithms developed in 2011 were published in the journal *Natural Hazards and Earth System Sciences* (Lato et al., 2012a) as well as presented at International conferences, e.g., at the "International Snow Science Workshop 2012” in Anchorage, Alaska (Lato et al., 2012b). Overall the developments have been accepted well within the community, the preliminary results demonstrate the possibility of numerous research and commercial applications. In parallel with the publication and presentation of the research results in 2012, new satellite images containing snow avalanche deposits were tested with the algorithms in eCognition. An overview of the data, the region it represents, as well as a discussion of the results is included in this document.Norges vassdrags- og energidirektorat (NVE), Region Ves

Using eCognition Definiens for automated detection of snow avalanches from optical imagery

Detection of avalanches from remotely collected optical imagery has been tested through analysis of image properties such as brightness, contrast, and different measures of texture. There have been few publications on the subject, providing an excellent opportunity for new developments. The work conducted at NGI in 2011 aimed at detecting fresh snow avalanches from very-high resolution (VHR) optical imagery. The research presented in this Technical Note has been supported by the Ministry of Petroleum and Energy (OED) through the Norwegian Water Resources and Energy Directorate (NVE).Norges Forskningsråd (NFR

Usefulness of the ManageMed Screen (MMS) and the Screening for Self-Medication Safety Post Stroke (S5) for Assessing Medication Management Capacity for Clients Post-Stroke

Occupational therapists need to efficiently and accurately screen a client’s medication management capacity, especially for clients post-stroke. Most therapists are not aware of, nor do they utilize specific assessments for, medication management capacity. The purpose of this pilot study was to compare the results of the ManageMed Screen (MMS), the Screening for Self-Medication Safety Post Stroke (S5), and the Montreal Assessment of Cognition (MoCA) on a population of rehabilitation clients post-stroke to determine the usefulness of the medication assessment tools in clinical practice. These screens were designed for use in occupational therapy practice among other healthcare professions: the MMS was validated for the general adult population, the S5 for clients post-stroke, and the MoCA is a cognitive screen used with adult clients with a variety of diagnoses including stroke. The MoCA was used to explore the potential relationship between cognition and medication management capacity. Study participants included five clients post-stroke and three occupational therapists. Clients were screened by the occupational therapists with the MMS, S5, and MoCA, and clinicians also participated in a focus group to assess their perceived usefulness of the screens. Results demonstrated that the MMS score compared to the S5 score was not statistically significant (r=.671, p=.215). There is no established consistency between the MoCA and MMS given these five clients. The MMS score was correlated to the MoCA score and was not found to be significant at a value of .205 with p=.741. The S5 score was also correlated to the MoCA score using SPSS and was found to have a non-significant value of -.287 and p=.640. Additionally, through a focus group, clinicians deemed both the MMS and S5 as useful, but felt the MMS was a more useful screen for their clinical practice with regard to efficient and practical use with clients post-stroke in a rehabilitation setting

Automated Avalanche Deposit Mapping From VHR Optical Imagery

Using eCognition we developed an algorithm to automatically detect and map avalanche deposits in Very High Resolution (VHR) optical remote sensing imagery acquired from satellites and airplanes. The algorithm relies on a cluster-based object-oriented image interpretation approach which employs segmentation and classification methodologies to identify avalanche deposits. The algorithm is capable of detecting avalanche deposits of varying size, composition, and texture. A discrete analysis of one data set (airborne imagery collected near Davos, Switzerland) demonstrates the capability of the algorithm. By comparing the automated detection results to the manually mapped results for the same image, 33 of the 35 manually digitized slides were correctly identified by the automated method. The automated mapping approach characterized 201 667 m2, of the image as being representative of a fresh snow avalanche, roughly 8.5% of the image. Through a spatial intersection between the manually mapped avalanches and the automatically mapped avalanches, 184 432 m2, or 89%, of the automatically mapped regions are spatially linked to the manually mapped regions. The rate of false positive was less than 1% of the pixels in the image. The initial results of the algorithm are promising, future development and implementation is currently being evaluated. The ability to automatically identify the location and extent of avalanche deposits using VHR optical imagery can assist in the development of detailed regional maps of zones historically prone to avalanches. This in turn can help to validate issued avalanche warnings

Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.

Bispecific antibodies are considered as a promising class of future biotherapeutic molecules. They comprise binding specificities for two different antigens, which may provide additive or synergistic modes of action. There is a wide variety of design alternatives for such bispecific antibodies, including the "CrossMab" format. CrossMabs contain a domain crossover in one of the antigen-binding (Fab) parts, together with the "knobs-and-holes" approach, to enforce the correct assembly of four different polypeptide chains into an IgG-like bispecific antibody. We determined the crystal structure of a hAng-2-binding Fab in its crossed and uncrossed form and show that CH1-CL-domain crossover does not induce significant perturbations of the structure and has no detectable influence on target binding

Zoonotic pathogens and antimicrobial resistance in ‘animal-friendly’ pig production systems in Switzerland

In a cross-sectional study, the impact of ‘animal-friendly’ housing systems on the prevalence of Salmonella species, Campylobacter species, and Yersinia enterocolitica in finishing pigs and pork was investigated. Furthermore, antimicrobial resistance patterns of isolated campylobacter strains were analysed. In faecal samples of two out of 88 fattening pig farms salmonellae were isolated. All 865 samples of pork were found to be negative. Campylobacter was isolated on 98.9 % of the farms but only from 0.2 % of the pork samples. Yersiniae were found in samples of 63.3 % of the farms and in 15.4 % of pork samples. For all three bacteria, there was no statistically significant difference in the prevalence between conventional and ‘animal-friendly’ housing systems. In ‘animal-friendly’ farms, antimicrobial resistance of campylobacter isolates to fluoroquinolones and streptomycin was significantly less frequent than in conventional farms. Furthermore, fewer isolates had resistance to three or more antimicrobials in ‘animal-friendly’ farms

In Vitro Activity of 3 Commercial Bacteriophage Cocktails Against Salmonella and Shigella spp. Isolates of Human Origin

Background: Salmonella and Shigella spp. are 2 of the most frequent and deadly enteric bacterial pathogens recorded worldwide. In developing countries Salmonella infections are responsible for many deaths annually and these mortality rates are prone to increase due to the emergence of resistance to antibiotics. In this overall scenario new alternative therapeutic approaches are needed. Methods: For the first time, we investigated the activity of 3 commercial bacteriophage cocktails (INTESTI, Septaphage, PYO) against a collection of contemporary Salmonella spp. (n = 30) and Shigella spp. (n = 20) strains isolated in Switzerland. Phage susceptibility was determined by implementing the spot test. Results: The overall susceptibility of Salmonella spp. to INTESTI and Septaphage was 87% and 77%, respectively. With regard to Shigella spp., the overall susceptibility to INTESTI and Septaphage was 95% and 55%, respectively. PYOwas observed to be active against only 10% of Salmonella spp. but against 95% of Shigella spp. Conclusions: Our results seem promising, especially for the INTESTI biopreparation against Salmonella enterica infections. Nevertheless, such speculation should be supported by further in vivo studies to confirm efficacy and safety of the cocktails. We also emphasize the importance of large in vitro screening analyses aimed to assess the activity of such biopreparations against contemporary multidrug-resistant strains that are emerging worldwide. Keywords: commercial; bacteriophages; Salmonella; Shigella cocktail