6,398 research outputs found
KINECTWheels: wheelchair-accessible motion-based game interaction
The increasing popularity of full-body motion-based video games creates new challenges for game accessibility research. Many games strongly focus on able-bodied persons and require players to move around freely. To address this problem, we introduce KINECTWheels, a toolkit that facilitates the integration of wheelchair-based game input. Our library can help game designers to integrate wheelchair input at the development stage, and it can be configured to trigger keystroke events to make off-the-shelf PC games wheelchair-accessible
Genome-wide linkage scan for loci associated with epilepsy in Belgian shepherd dogs.
BackgroundIdiopathic epilepsy in the Belgian shepherd dog is known to have a substantial genetic component. The objective of this study was to identify genomic regions associated with the expression of generalized seizures in the Belgian Tervuren and Sheepdog.ResultsDNA from 366 dogs, of which 74 were classified as epileptic, representing two extended families were subjected to a genome-wide linkage scan using 410 microsatellite markers yielding informative coverage averaging 5.95 +/- 0.21 Mb. Though previous studies based on pedigree analyses proposed a major gene of influence, the present study demonstrated the trait to be highly polygenic. Studies of complex disorders in humans indicate that a liberal composite evaluation of genetic linkage is needed to identify underlying quantitative trait loci (QTLs). Four chromosomes yielded tentative linkage based upon LOD scores in excess of 1.0. Possible QTLs within these regions were supported also by analyses of multipoint linkage, allele frequency, TDT, and transmission of haplotype blocks.ConclusionsTaken together the data tentatively indicate six QTLs, three on CFA 2, and one on each of CFA 6, 12, and 37, that support fine mapping for mutations associated with epilepsy in the Belgian shepherd. The study also underscores the complexity of genomic linkage studies for polygenic disorders
A global magnetic anomaly map
A subset of POGO satellite magnetometer data has been formed that is suitable for analysis of crustal magnetic anomalies. Using a thirteenth order field model, fit to these data, magnetic residuals have been calculated over the world to latitude limits of plus 50 deg. These residuals averaged over one degree latitude-longitude blocks represent a detailed global magnetic anomaly map derived solely from satellite data. Preliminary analysis of the map indicates that the anomalies are real and of geological origin
General CMB and Primordial Trispectrum Estimation
We present trispectrum estimation methods which can be applied to general
non-separable primordial and CMB trispectra. We present a general optimal
estimator for the connected part of the trispectrum, for which we derive a
quadratic term to incorporate the effects of inhomogeneous noise and masking.
We describe a general algorithm for creating simulated maps with given
arbitrary (and independent) power spectra, bispectra and trispectra. We propose
a universal definition of the trispectrum parameter , so that the
integrated bispectrum on the observational domain can be consistently compared
between theoretical models. We define a shape function for the primordial
trispectrum, together with a shape correlator and a useful parametrisation for
visualizing the trispectrum. We derive separable analytic CMB solutions in the
large-angle limit for constant and local models. We present separable mode
decompositions which can be used to describe any primordial or CMB bispectra on
their respective wavenumber or multipole domains. By extracting coefficients of
these separable basis functions from an observational map, we are able to
present an efficient estimator for any given theoretical model with a
nonseparable trispectrum. The estimator has two manifestations, comparing the
theoretical and observed coefficients at either primordial or late times. These
mode decomposition methods are numerically tractable with order
operations for the CMB estimator and approximately order for the general
primordial estimator (reducing to order in both cases for a special class
of models). We also demonstrate how the trispectrum can be reconstructed from
observational maps using these methods.Comment: 38 pages, 9 figures. In v2 Figures 4-7 are altered slightly and some
extra references are included in the bibliography. v3 matches version
submitted to journal. Includes discussion of special case
Universal Non-Gaussian Initial Conditions for N-body Simulations
In this paper we present the implementation of an efficient formalism for the
generation of arbitrary non-Gaussian initial conditions for use in N-body
simulations. The methodology involves the use of a separable modal approach for
decomposing a primordial bispectrum or trispectrum. This approach allows for
the far more efficient generation of the non-Gaussian initial conditions
already described in the literature, as well as the generation for the first
time of non-separable bispectra and the special class of diagonal-free
trispectra. The modal approach also allows for the reconstruction of the
spectra from given realisations, a fact which is exploited to provide an
accurate consistency check of the simulations.Comment: 7 pages, 3 figure
Rapid Separable Analysis of Higher Order Correlators in Large Scale Structure
We present an efficient separable approach to the estimation and
reconstruction of the bispectrum and the trispectrum from observational (or
simulated) large scale structure data. This is developed from general CMB
(poly-)spectra methods which exploit the fact that the bispectrum and
trispectrum in the literature can be represented by a separable mode expansion
which converges rapidly (with terms). With an
effective grid resolution (number of particles/grid points
), we present a bispectrum estimator which requires only
operations, along with a
corresponding method for direct bispectrum reconstruction. This method is
extended to the trispectrum revealing an estimator which requires only operations. The complexity in
calculating the trispectrum in this method is now involved in the original
decomposition and orthogonalisation process which need only be performed once
for each model. However, for non-diagonal trispectra these processes present
little extra difficulty and may be performed in
operations. A discussion of how the methodology may be applied to the
quadspectrum is also given. An efficient algorithm for the generation of
arbitrary nonGaussian initial conditions for use in N-body codes using this
separable approach is described. This prescription allows for the production of
nonGaussian initial conditions for arbitrary bispectra and trispectra. A brief
outline of the key issues involved in parameter estimation, particularly in the
non-linear regime, is also given
Improved definition of crustal magnetic anomalies for MAGSAT data
The routine correction of MAGSAT vector magnetometer data for external field effects such as the ring current and the daily variation by filtering long wavelength harmonics from the data is described. Separation of fields due to low altitude sources from those caused by high altitude sources is affected by means of dual harmonic expansions in the solution of Dirichlet's problem. This regression/harmonic filter procedure is applied on an orbit by orbit basis, and initial tests on MAGSAT data from orbit 1176 show reduction in external field residuals by 24.33 nT RMS in the horizontal component, and 10.95 nT RMS in the radial component
Riding the Third Wave of SoTL
Taking stock of an enterprise can be a stimulating exercise. It is also an essential one that allows for assessment of what one has while facilitating the planning of what one wants. In this piece, we take stock of the scholarship of teaching and learning (SoTL), mapping out what we see as the first two waves of the movement, and then identifying a ‘third wave.’ We believe it is time to think bigger. Specifically, those practicing SoTL need to: infiltrate the mainstream, run interference and catalyze the use of SoTL, and work towards a grand picture of learning
The suppression of superconductivity in MgCNi3 by Ni-site doping
The effects of partial substitution of Cu and Co for Ni in the intermetallic
perovskite superconductor MgCNi3 are reported. Calculation of the expected
electronic density of states suggests that electron (Cu) and hole (Co) doping
should have different effects. For MgCNi3-xCux, solubility of Cu is limited to
approximately 3% (x = 0.1), and Tc decreases systematically from 7K to 6K. For
MgCNi3-xCox, solubility of Co is much more extensive, but bulk
superconductivity disappears for Co doping of 1% (x = 0.03). No signature of
long range magnetic ordering is observed in the magnetic susceptibility of the
Co doped material.Comment: submitted, Solid State Communication
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