12,354 research outputs found
Isotopic enrichment of nitrogen in the photolysis of NO
Isotopic enrichment of nitrogen in photolysis of N
Science leadership for tomorrow: The role of schools of public affairs and universities in meeting needs of public science agencies
Recommendations and requirements for the preparation of personnel with some scientific or technological background to enter fields of public policy and administration are reported. University efforts to provide science administration graduate programs are outlined and increased cooperation between government and university resources is outlined
Performance of charge-injection-device infrared detector arrays at low and moderate backgrounds
Three 2 x 64 element charge injection device infrared detector arrays were tested at low and moderate background to evaluate their usefulness for space based astronomical observations. Testing was conducted both in the laboratory and in ground based telescope observations. The devices showed an average readout noise level below 200 equivalent electrons, a peak responsivity of 4 A/W, and a noise equivalent power of 3x10 sq root of W/Hz. Array well capacity was measured to be significantly smaller than predicted. The measured sensitivity, which compares well with that of nonintegrating discrete extrinsic silicon photoconductors, shows these arrays to be useful for certain astronomical observations. However, the measured readout efficiency and frequency response represent serious limitations in low background applications
Dynamics of a combined Medea-underdominant population transformation system
Background: Transgenic constructs intended to be stably established at high frequencies in wild populations have been demonstrated to ādriveā from low frequencies in experimental insect populations. Linking such population transformation constructs to genes which render them unable to transmit pathogens could eventually be used to stop the spread of vector-borne diseases like malaria and dengue. Results: Generally, population transformation constructs with only a single transgenic drive mechanism have been envisioned. Using a theoretical modelling approach we describe the predicted properties of a construct combining autosomal Medea and underdominant population transformation systems. We show that when combined they can exhibit synergistic properties which in broad circumstances surpass those of the single systems. Conclusion: With combined systems, intentional population transformation and its reversal can be achieved readily. Combined constructs also enhance the capacity to geographically restrict transgenic constructs to targeted populations. It is anticipated that these properties are likely to be of particular value in attracting regulatory approval and public acceptance of this novel technology
A common gene drive language eases regulatory process and eco-evolutionary extensions
Background Synthetic gene drive technologies aim to spread transgenic constructs into wild populations even when they impose organismal fitness disadvantages. The extraordinary diversity of plausible drive mechanisms and the range of selective parameters they may encounter makes it very difficult to convey their relative predicted properties, particularly where multiple approaches are combined. The sheer number of published manuscripts in this field, experimental and theoretical, the numerous techniques resulting in an explosion in the gene drive vocabulary hinder the regulators' point of view. We address this concern by defining a simplified parameter based language of synthetic drives. Results Employing the classical population dynamics approach, we show that different drive construct (replacement) mechanisms can be condensed and evaluated on an equal footing even where they incorporate multiple replacement drives approaches. Using a common language, it is then possible to compare various model properties, a task desired by regulators and policymakers. The generalization allows us to extend the study of the invasion dynamics of replacement drives analytically and, in a spatial setting, the resilience of the released drive constructs. The derived framework is available as a standalone tool. Conclusion Besides comparing available drive constructs, our tool is also useful for educational purpose. Users can also explore the evolutionary dynamics of future hypothetical combination drive scenarios. Thus, our results appraise the properties and robustness of drives and provide an intuitive and objective way for risk assessment, informing policies, and enhancing public engagement with proposed and future gene drive approaches
A simultaneous XMM-Newton and BeppoSAX observation of the archetypal Broad Line Seyfert 1 galaxy NGC 5548
We report the spectral analysis of a long XMM-Newton observation of the
well-studied, moderate luminosity Broad Line Seyfert 1 galaxy NGC 5548. The
source was at an historically average brightness and we find the hard (3-10
keV) spectrum can be well fitted by a power law of photon index gamma ~ 1.75,
together with reflection. The only feature in the hard X-ray spectrum is a
narrow emission line near 6.4 keV, with an equivalent width of ~ 60 eV. The
energy and strength of this line is consistent with fluorescence from `neutral'
iron distant from the central continuum source. We find no evidence for a broad
Fe K line, with an upper limit well below previous reports, suggesting the
inner accretion disc is now absent or highly ionised. The addition of
simultaneous BeppoSAX data allows the analysis to be extended to 200 keV,
yielding important constraints on the total reflection. Extrapolation of the
hard X-ray power law down to 0.3 keV shows a clear `soft excess' below ~ 0.7
keV. After due allowance for the effects of a complex warm absorber, measured
with the XMM-Newton RGS, we find the soft excess is better described as a
smooth upward curvature in the continuum flux below ~ 2 keV. The soft excess
can be modelled either by Comptonised thermal emission or by enhanced
reflection from the surface of a highly ionised disc.Comment: 9 pages, 11 figures, accepted by MNRAS; minor changes to text and
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First Season QUIET Observations: Measurements of Cosmic Microwave Background Polarization Power Spectra at 43 GHz in the Multipole Range 25 ā¤ ā ā¤ 475
The Q/U Imaging ExperimenT (QUIET) employs coherent receivers at 43 GHz and 94 GHz, operating on the Chajnantor plateau in the Atacama Desert in Chile, to measure the anisotropy in the polarization of the cosmic microwave background (CMB). QUIET primarily targets the B modes from primordial gravitational waves. The combination of these frequencies gives sensitivity to foreground contributions from diffuse Galactic synchrotron radiation. Between 2008 October and 2010 December, over 10,000 hr of data were collected, first with the 19 element 43 GHz array (3458 hr) and then with the 90 element 94 GHz array. Each array observes the same four fields, selected for low foregrounds, together covering ā1000 deg^2. This paper reports initial results from the 43 GHz receiver, which has an array sensitivity to CMB fluctuations of 69 Ī¼Kās. The data were extensively studied with a large suite of null tests before the power spectra, determined with two independent pipelines, were examined. Analysis choices, including data selection, were modified until the null tests passed. Cross-correlating maps with different telescope pointings is used to eliminate a bias. This paper reports the EE, BB, and EB power spectra in the multipole range ā = 25-475. With the exception of the lowest multipole bin for one of the fields, where a polarized foreground, consistent with Galactic synchrotron radiation, is detected with 3Ļ significance, the E-mode spectrum is consistent with the ĪCDM model, confirming the only previous detection of the first acoustic peak. The B-mode spectrum is consistent with zero, leading to a measurement of the tensor-to-scalar ratio of r = 0.35^(+1.06)_(ā0.87). The combination of a new time-stream "double-demodulation" technique, side-fed Dragonian optics, natural sky rotation, and frequent boresight rotation leads to the lowest level of systematic contamination in the B-mode power so far reported, below the level of r = 0.1
Unification of X-ray winds in Seyfert galaxies: from ultra-fast outflows to warm absorbers
The existence of ionized X-ray absorbing layers of gas along the line of
sight to the nuclei of Seyfert galaxies is a well established observational
fact. This material is systematically outflowing and shows a large range in
parameters. However, its actual nature and dynamics are still not clear. In
order to gain insights into these important issues we performed a literature
search for papers reporting the parameters of the soft X-ray warm absorbers
(WAs) in 35 type 1 Seyferts and compared their properties to those of the
ultra-fast outflows (UFOs) detected in the same sample. The fraction of sources
with WAs is >60%, consistent with previous studies. The fraction of sources
with UFOs is >34%, >67% of which also show WAs. The large dynamic range
obtained when considering all the absorbers together allows us, for the first
time, to investigate general relations among them. In particular, we find
significant correlations indicating that the closer the absorber is to the
central black hole, the higher the ionization, column, outflow velocity and
consequently the mechanical power. The absorbers continuously populate the
whole parameter space, with the WAs and the UFOs lying always at the two ends
of the distribution. This strongly suggest that these absorbers, often
considered of different types, could actually represent parts of a single
large-scale stratified outflow observed at different locations from the black
hole. The observed parameters and correlations are consistent with both
radiation pressure through Compton scattering and MHD processes contributing to
the outflow acceleration, the latter playing a major role. Most of the
absorbers, especially the UFOs, have a sufficiently high mechanical power to
significantly contribute to AGN feedback.Comment: Manuscript updated to match the MNRAS published version. Link to the
related INAF news: http://www.media.inaf.it/2013/02/05/warm-absorbers
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