3,609 research outputs found
Effect of the boundary layer upon the flow in a conical hypersonic nozzle
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76641/1/AIAA-2269-288.pd
Thermal activation of ferroelectric switching
By applying the theory of thermally activated nucleation to the switching of ferroelectric domains, a method is developed to experimentally obtain the value of both the activation enthalpy, ΔH, and activation volume, V*, for the thermally activated process involved in ferroelectric switching. The method was applied to the switching of a soft lead zirconate titanate and values of ΔH = (0.16±0.02) eV and V* = (1.62±0.16)×10−25 m3 were obtained at the coercive field. These values imply that the energy, ΔU, required for the formation of switching nuclei is mainly supplied by the work done by the electric field. A comparison of these values with those obtained from theoretical considerations suggests that the switching is achieved by the sideways expansion of nuclei formed at the domain boundaries in the form of low amplitude and long wavelength fluctuations of the domain walls
Model for initiation of quality factor degradation at high accelerating fields in superconducting radio-frequency cavities
A model for the onset of the reduction in SRF cavity quality factor, the
so-called Q-drop, at high accelerating electric fields is presented. Breakdown
of the surface barrier against magnetic flux penetration at the cavity equator
is considered to be the critical event that determines the onset of Q-drop. The
worst case of triangular grooves with low field of first flux penetration Hp,
as analyzed previously by Buzdin and Daumens, [1998 Physica C 294: 257], was
adapted. This approach incorporates both the geometry of the groove and local
contamination via the Ginzburg-Landau parameter kappa, so the proposed model
allows new comparisons of one effect in relation to the other. The model
predicts equivalent reduction of Hp when either roughness or contamination were
varied alone, so smooth but dirty surfaces limit cavity performance about as
much as rough but clean surfaces do. When in combination, contamination
exacerbates the negative effects of roughness and vice-versa. To test the model
with actual data, coupons were prepared by buffered chemical polishing and
electropolishing, and stylus profilometry was used to obtain distributions of
angles. From these data, curves for surface resistance generated by simple flux
flow as a function of magnetic field were generated by integrating over the
distribution of angles for reasonable values of kappa. This showed that
combined effects of roughness and contamination indeed reduce the Q-drop onset
field by ~30%, and that that contamination contributes to Q-drop as much as
roughness. The latter point may be overlooked by SRF cavity research, since
access to the cavity interior by spectroscopy tools is very difficult, whereas
optical images have become commonplace. The model was extended to fit cavity
test data, which indicated that reduction of the superconducting gap by
contaminants may also play a role in Q-drop.Comment: 15 pages with 7 figure
Production and detection of relic gravitons in quintessential inflationary models
A large class of quintessential inflationary models, recently proposed by
Peebles and Vilenkin, leads to post-inflationary phases whose effective
equation of state is stiffer than radiation. The expected gravitational waves
logarithmic energy spectra are tilted towards high frequencies and
characterized by two parameters: the inflationary curvature scale at which the
transition to the stiff phase occurs and the number of (non conformally
coupled) scalar degrees of freedom whose decay into fermions triggers the onset
of a gravitational reheating of the Universe. Depending upon the parameters of
the model and upon the different inflationary dynamics (prior to the onset of
the stiff evolution) the relic gravitons energy density can be much more
sizeable than in standard inflationary models, for frequencies larger than 1
Hz. We estimate the required sensitivity for detection of the predicted
spectral amplitude and show that the allowed region of our parameter space
leads to a signal smaller (by one 1.5 orders of magnitude) than the advanced
LIGO sensitivity at a frequency of 0.1 KHz. The maximal signal, in our context,
is expected in the GHz region where the energy density of relic gravitons in
critical units (i.e. ) is of the order of , roughly
eight orders of magnitude larger than in ordinary inflationary models. Smaller
detectors (not necessarily interferometers) can be relevant for detection
purposes in the GHz frequency window. We suggest/speculate that future
measurements through microwave cavities can offer interesting perspectives.Comment: 24 pages in Revtex style, 7 figure
BLUF Domain Function Does Not Require a Metastable Radical Intermediate State
BLUF
(blue light using flavin) domain proteins are an important
family of blue light-sensing proteins which control a wide variety
of functions in cells. The primary light-activated step in the BLUF
domain is not yet established. A number of experimental and theoretical
studies points to a role for photoinduced electron transfer (PET)
between a highly conserved tyrosine and the flavin chromophore to
form a radical intermediate state. Here we investigate the role of
PET in three different BLUF proteins, using ultrafast broadband transient
infrared spectroscopy. We characterize and identify infrared active
marker modes for excited and ground state species and use them to
record photochemical dynamics in the proteins. We also generate mutants
which unambiguously show PET and, through isotope labeling of the
protein and the chromophore, are able to assign modes characteristic
of both flavin and protein radical states. We find that these radical
intermediates are not observed in two of the three BLUF domains studied,
casting doubt on the importance of the formation of a population of
radical intermediates in the BLUF photocycle. Further, unnatural amino
acid mutagenesis is used to replace the conserved tyrosine with fluorotyrosines,
thus modifying the driving force for the proposed electron transfer
reaction; the rate changes observed are also not consistent with a
PET mechanism. Thus, while intermediates of PET reactions can be observed
in BLUF proteins they are not correlated with photoactivity, suggesting
that radical intermediates are not central to their operation. Alternative
nonradical pathways including a keto–enol tautomerization induced
by electronic excitation of the flavin ring are considered
Low-Energy Signals from Kinetic Mixing with a Warped Abelian Hidden Sector
We investigate the detailed phenomenology of a light Abelian hidden sector in
the Randall-Sundrum framework. Relative to other works with light hidden
sectors, the main new feature is a tower of hidden Kaluza-Klein vectors that
kinetically mix with the Standard Model photon and Z. We investigate the decay
properties of the hidden sector fields in some detail, and develop an approach
for calculating processes initiated on the ultraviolet brane of a warped space
with large injection momentum relative to the infrared scale. Using these
results, we determine the detailed bounds on the light warped hidden sector
from precision electroweak measurements and low-energy experiments. We find
viable regions of parameter space that lead to significant production rates for
several of the hidden Kaluza-Klein vectors in meson factories and fixed-target
experiments. This offers the possibility of exploring the structure of an extra
spacetime dimension with lower-energy probes.Comment: (1+32) Pages, 13 Figures. v2: JHEP version (minor modifications,
results unchanged
Carbon nanomaterials for targeted cancer therapy drugs: a critical review.
Cancer represents one of the main causes of human death in developed countries. Most current therapies, unfortunately, carry a number of side effects, such as toxicity and damage to healthy cells, as well as the risk of resistance and recurrence. Therefore, cancer research is trying to develop therapeutic procedures with minimal negative consequences. The use of nanomaterial-based systems appears to be one of them. In recent years, great progress has been made in the field of possible use of nanomaterials with high potential in biomedical applications. Carbon nanomaterials, thanks to their unique physicochemical properties, are gaining more and more popularity in cancer therapy. They are valued especially for their ability to deliver drugs or small therapeutic molecules to these cells. Through surface functionalization, they can specifically target tumor tissues, increasing the therapeutic potential and significantly reducing the adverse effects of therapy. Their potential future use could, therefore, as vehicles for drug delivery. This review presents the latest findings of research studies using carbon nanomaterials in the treatment of various types of cancer. To carry out this study, different databases such as Web of Science, PubMed, MEDLINE and Google Scholar were employed. The findings of research studies chosen from more than 2000 viewed scientific publications from the last 15 years were compared
Fatigue of Yttria-Stabilized Zirconia: II, Crack Propagation, Fatigue Striations, and Short-Crack Behavior
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65604/1/j.1151-2916.1991.tb04089.x.pd
Effective AdS/renormalized CFT
For an effective AdS theory, we present a simple prescription to compute the
renormalization of its dual boundary field theory. In particular, we define
anomalous dimension holographically as the dependence of the wave-function
renormalization factor on the radial cutoff in the Poincare patch of AdS. With
this definition, the anomalous dimensions of both single- and double- trace
operators are calculated. Three different dualities are considered with the
field theory being CFT, CFT with a double-trace deformation and spontaneously
broken CFT. For the second dual pair, we compute scaling corrections at the UV
and IR fixed points of the RG flow triggered by the double-trace deformation.
For the last case, we discuss whether our prescription is sensitive to the AdS
interior or equivalently, the IR physics of the dual field theory.Comment: 20 pages, 3 figure
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