Case study on costs and efficiency of Urgent Care Center Desert Valley Medical Group, Victorville

The purpose of this research project is to report on a comprehensive organizational audit of the Urgent Care Service of Desert Valley Medical Group in Victorville, California

Synthesis and Characterization of Sugar Based Low Molecular Weight Gelators and the Preparation of Chiral Sulfinamides

Low molecular weight gelators (LMWGs) have received considerable attention in the field of chemistry from last few decades. These compounds form self-assembled fibrous networks like micelles, cylindrical, sheets, fibers, layers and so on. The fibrous network entraps the solvent and forms gel, because of the self-assembly phenomenon and their demonstrated potential uses in a variety of areas, ranging from environmental to medicinal applications. Sugars are good starting materials to synthesize the new class of LMWG\u27s, because these are different from some expensive materials, these are natural products. We have synthesized and characterized the LMGS\u27s based on D-glucose and D-glucosamine. D-glucosamine is the versatile starting material to make different peptoids and triazoles. Several series of compounds were synthesized using compounds 1-3 as starting material and studied the gelation behavior all the compounds. We have studied the self-assembling properties of a new class of tripeptoids, synthesized by one-pot Ugi reaction from simple starting materials. Among the focused library of tripeptoids synthesized, we found that several efficient low molecular weight organogelators were obtained for aqueous DMSO and ethanol mixtures. We have also synthesized and characterized a series of monosaccharide triazole derivatives. These compounds were synthesized from N-acetyl glucosamine and D-glucose via a Cu(I) catalyzed azide/alkyne cycloaddition reaction (CuAAc). The compounds have been screened for their gelation properties and several efficient low molecular weight organo/hydro gelators were obtained, among these compounds, five per-acetyl glucosamine derivatives and one peracetyl glucose derivative were able to form gels in water. These new molecules are expected to be useful in drug delivery and tissue engineering.* Asymmetric synthesis of chiral amines is a challenging in synthetic organic chemistry. The development of new catalysts for asymmetric organic transformations is a very important research goal in modern synthetic organic chemistry. We have synthesized a new class of chiral oxathiozinone from chiral amino phenol. From this synthesized chiral sulfinamides, ketimines followed by reducing the ketimines synthesized the highly hindered chiral amines

A Study Of Flexural With Cut Off Intensification Of RC Joist

This study presents a final report on adaptive concrete adjustment / bonding system for flexural conditioning of RC participants. The use of adhesive tape in this system has actually reduced the elastic modulus when extending as much as tensile crack. Thus, the bonding line between FRP and concrete can generate a huge shear deviation to delay or prevent the regional UI removal event. Derived from FRP panels / concrete user interface withdrawal tests, research lab tests on constant efficiency along with participant depletion in RC reinforced with FRP sheets, and also reported a complete inspection on a 15m T-beam at this paper. Failed systems for reinforcing participants in typical bonding situations as well as relatively adaptable bonding systems are inspected. In contrast to the typical bonding system, the versatile system has already confirmed its attractive validity in improving the RC spotlight beam for improved stiffness and deformation. However, this method is preferred for the maximum constraint boost function only because it adds a less rigid optimization under the Restricted Service Condition

A study of age as a risk factor in ischemic stroke of elderly

Background: The aim of the study was to determine the effect of age as a risk factor and a determinant of outcome in elderly ischemic stroke patients.Methods: This is an observational study. One hundred, successive elderly patients aged 60 years and above, admitted with acute ischemic stroke in PESIMSR over a period of 18 months were prospectively studied. Patients with hemorrhagic stroke, neurological deficits following trauma or following infection were excluded. Demographics, risk factors, stroke severity at admission were estimated by NIHSS. Risk factors and clinical profile were noted and compared among male and female patients. Outcome at discharge was measured by-mRS-modified ranking score.Results: Patients in age group 60-75 years presented with less severe stroke and better mRS when compared to >75 years age group. Complications were significantly higher among the older age group.Conclusions: The risk factors identified for ischemic stroke in the present study are diabetes, hypertension, dyslipidaemia, obesity, smoking, and alcohol. Severity of stroke at presentation, clinical outcome and complication rate during the in-hospital stay were all significantly affected by the age, more so in ischemic stroke. Age specific factors of stroke prevention are crucial for successful prevention and implementation of well-organized stroke care

OFDM Channel Estimation Along with Denoising Approach under Small SNR Environment using SSA

In this paper, a de-noising approach in conjunction with channel estimation (CE) algorithm for OFDM systems using singular spectrum analysis (SSA) is presented. In the proposed algorithm, the initial CE is computed with the aid of traditional linear minimum mean square error (LMMSE) algorithm, and then further channel is evaluated by considering the low rank eigenvalue approximation of channel correlation matrix related to channel using SSA. Simulation results on bit error rate (BER) revealed that the method attains an improvement of 7 dB, 5 dB and 3 dB compared to common LSE, MMSE and SVD based methods respectively. With the help of statistical correlation coefficient (C) and kurtosis (k), the SSA method utilized to de-noise the received OFDM signal in addition to CE. In the process of denoising, the received OFDM signal will be decomposed into different empirical orthogonal functions (EOFs) based on the singular values. It was established that the correlation coefficients worked well in identifying useful EOFs only up to moderate (SNR geq 12dB). For low SNR<12 dB, kurtosis was found to be a useful measure for identifying the useful EOFs. In addition to outperforming the existing methods, with this de-noising approach, the mean square error (MSE) of channel estimator is further improved approximately 1 dB more in SNR at the cost of computational complexity

ASSESSMENT OF SERUM LIPID PROFILE IN HYPERTENSIVE PATIENTS: A CASE-CONTROL STUDY

Background: Hypertension and dyslipidemia are strongly associated with each other, and they are the most common risk factors for the development of the cardiovascular disease. Aim: Compare the serum lipid profile values among hypertensive patients and non-hypertensive individuals. Method: 30 patients with Hypertension and 30 age-matched non-hypertensive controls were included in the study. From the serum, total cholesterol levels were estimated by enzymatic (CHOD-PAP) colorimetric method, triglyceride by enzymatic (GPO-PAP) method, HDL-cholesterol and LDL-cholesterol were estimated using precipitant and Friedewald formula, by using commercially available reagent kits. Lipid profiles were compared with controls. Results: The mean values of total cholesterol were significantly more in Hypertensives-202.93 ± 28.44 and normotensives-178.76 ± 37.21, P&lt;0.006. The mean values of triglycerides were significantly more in Hypertensives-139.8 ± 18.72 and normotensives-125.8± 12.34, P&lt;0.001. The mean values of LDL-Cholesterol were significantly more in Hypertensives-141.63 ± 11.59 and normotensives-127.83 ± 14.65, P&lt;0.0001. Conclusions: As Dyslipidemia is associated with Hypertension, serum lipid profile may be useful in the identification of patients at risk of Hypertension. Hypertensive patients need the measurement of blood pressure and lipid profile at regular intervals to prevent Cardiovascular diseases. Keywords: Cholesterol; Cardiovascular Diseases; Hypertension; Triglycerides; Dyslipidemia

ASSESSMENT OF SERUM LIPID PROFILE IN HYPERTENSIVE PATIENTS: A CASE-CONTROL STUDY

Background: Hypertension and dyslipidemia are strongly associated with each other, and they are the most common risk factors for the development of the cardiovascular disease. Aim: Compare the serum lipid profile values among hypertensive patients and non-hypertensive individuals. Method: 30 patients with Hypertension and 30 age-matched non-hypertensive controls were included in the study. From the serum, total cholesterol levels were estimated by enzymatic (CHOD-PAP) colorimetric method, triglyceride by enzymatic (GPO-PAP) method, HDL-cholesterol and LDL-cholesterol were estimated using precipitant and Friedewald formula, by using commercially available reagent kits. Lipid profiles were compared with controls. Results: The mean values of total cholesterol were significantly more in Hypertensives-202.93 ± 28.44 and normotensives-178.76 ± 37.21, P&lt;0.006. The mean values of triglycerides were significantly more in Hypertensives-139.8 ± 18.72 and normotensives-125.8± 12.34, P&lt;0.001. The mean values of LDL-Cholesterol were significantly more in Hypertensives-141.63 ± 11.59 and normotensives-127.83 ± 14.65, P&lt;0.0001. Conclusions: As Dyslipidemia is associated with Hypertension, serum lipid profile may be useful in the identification of patients at risk of Hypertension. Hypertensive patients need the measurement of blood pressure and lipid profile at regular intervals to prevent Cardiovascular diseases. Keywords: Cholesterol; Cardiovascular Diseases; Hypertension; Triglycerides; Dyslipidemia

Laboratory Testing and Mechanistic Analysis of Treated Subgrade Soils

Calcium-based stabilizing agents such as cement and lime have been extensively used to improve the engineering properties of base and subgrade layers of pavement systems. Recently, polymers and chemical stabilizers have become popular due to cost efficiency, ease of application, and fast curing times. In this study, California Bearing Ratio (CBR) values of polymer and chemical treated soils were compared with the CBR values of soils treated with conventional stabilizers. Parametric sensitivity analyses was carried out on key parameters including the type of subgrade soil, stabilizing agent, stabilizing agent treatment levels, and moisture conditioning. Additionally, numerical analyses was performed to explore the impact of various admixtures on the design life of pavement systems. Finally, a cost-effectiveness analysis was performed to determine the economic benefits of stabilizing agents. It was documented that stabilizing agents significantly enhanced the performance of subgrade soils