Billu

This is a review of Billu (2009)

Delhi 6

This is a review of Delhi 6 (2009)

The Guttman Approach to Modeling Drug Sequences: Bridging Literature Gaps

In addressing several literature gaps in the drug sequencing literature, this study investigated the sequencing of alcohol, cigarette, and marijuana initiation among a sample of rural American youth, by using age of initiation data to develop a Guttman scale of soft drug involvement. Explicit attention was paid to the role and importance of cigarette initiation in the soft drug sequence and an effort was made to determine whether the scalability of the sequence is impacted by the type of drug measures employed. To attend to these lines of inquiry, two Guttman scales were used to test a modified version of Kandel’s (1975, 2002) drug sequencing hypothesis. The first scale utilized age of initiation data, while the second scale was developed with dichotomous initiation measures. Cross-sectional data were derived from a rural sample of American 6th, 9th, and 12th grade students. The type of initiation measures utilized had a direct bearing on scale fit and the degree to which the hypothesis was supported. Indicated are the implications that the findings have for school-based drug prevention programs. Keywords: Guttman scale; cigarette initiation in the soft drug sequence; Modeling Drug Sequences Résumé: Afin de combler les lacunes documentaires dans le séquençage de drogue, cette étude a étudié le séquençage de l'alcool, de la cigarette et de l'initiation de marijuana auprès d'un échantillon de jeunes américains en milieu rural, en utilisant des données d'âge d'initiation à développer une échelle de Guttman de l'utilisation de drogue douce. Une attention explicite a été accordée au rôle et à l'importance de l'initiation de cigarette dans la séquence de drogue douce et un effort a été fait afin de déterminer si l'évolutivité de la séquence est affectée par le type de mesures de drogue employé. Afin d'assister à ces lignes de l'enquête, deux échelles de Guttman ont été utilisées à tester une version modifiée de l'hypothèse de séquençage de drogue de Kandel (1975, 2002). La première échelle a utilisé les données d'âge d'initiation, tandis que la deuxième échelle a été développée avec des mesures d'initiation dichotomiques. Des données trans-sectionnelles ont été calculées à partir d'un échantillon des étudiants américains ruraux en 6ème, 9ème et 12ème année. Le type de mesures d'initiation utilisées a une incidence directe sur l'ajustement d'échelle et la mesure dans laquelle l'hypothèse a été soutenue. Les résultats utiles pour des programmes de prévention de la toxicomanie dans l'école. Mots-clés: échelle de Guttman; initiation de cigarette dans la séquence de drogue douce; modélisation de séquences de drogu

Model file name: beta-sheet_rod 0.7.dae

Model file name: beta-sheet_rod 0.7.dae Authors: Michelle E Howell, Rebecca L Roston This is a teaching model of a stick representation of a protein β-sheet (PDB: 3vjo). This model is designed to accompany three other α-helix models: a space-fill representation of a straight α-helix, a stick representation of a straight α-helix, and a stick representation of a kinked α-helix. These models accompany a teaching module illustrating protein secondary structure and function. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Beta-sheet_Thick”. This model has been printed successfully using these parameters on Shapeways’ binder jetting printer in the Coated Full Color Sandstone material

Cytochrome c: Model file name: 1b7v-cytc-stick_sc1-5.stl

This is a teaching model of cytochrome c (PDB: 1B7V). It is designed in a stick representation to explore protein secondary structure and how much space the protein takes up. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Cytochrome c” and is intended to accompany the “Lipoprotein signal peptidase II”, “Crambin”, and “3 water molecules” models. This model has been printed successfully using these parameters on Shapeways’ laser sintering printer in the following material: Processed Versatile Plastic (Strong & Flexible Plastic)

Crambin: Model file name: 2fd7-crambin-stick_sc1-5.stl

This is a teaching model of cytochrome c (PDB: 2FD7). It is designed in a stick representation to explore protein secondary structure and how much space the protein takes up. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Crambin” and is intended to accompany the “Lipoprotein signal peptidase II”, “Cytochrome c”, and “3 water molecules” models. This model has been printed successfully using these parameters on Shapeways’ laser sintering printer in the following material: Processed Versatile Plastic (Strong & Flexible Plastic)

Model file name: alpha helix pro-gly 0.7.dae

Model file name: alpha helix pro-gly 0.7.dae Authors: Michelle E Howell, Rebecca L Roston This is a teaching model of a stick representation of a protein α-helix with proline and glycine residues highlighted (PDB: 3vjo). This model is designed to accompany a straight α-helix in space fill representation, a straight α-helix in stick representation, and a stick β-sheet model as well as a teaching module illustrating protein secondary structure and function. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Alpha Helix_Pro-Gly”. This model has been printed successfully using these parameters on Shapeways’ binder jetting printer in the Coated Full Color Sandstone material

Model file name: alpha helix 0.7.dae

Model file name: alpha helix 0.7.dae Authors: Michelle E Howell, Rebecca L Roston This is a teaching model of a stick representation of a protein α-helix (PDB: 3vjo). This model can accompany a corresponding space fill representation, a kinked α-helix, and a β-sheet. These models were designed to accompany a teaching module illustrating protein secondary structure and function. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Alpha Helix_Thick”. This model has been printed successfully using these parameters on Shapeways’ binder jetting printer in the Coated Full Color Sandstone material

Lipoprotein signal peptidase II: Model file name: 5dir-LipoII-reps_sc1-5.stl

This is a teaching model of lipoprotein signal peptidase II (PDB: 5DIR). It is designed with different regions of the protein depicted in space-filling, ribbon, stick, and backbone-only representations to explore protein secondary structure and illustrate how much space the protein takes up. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Lipoprotein signal peptidase II” and is intended to accompany the “Crambin”, “Cytochrome c” and “3 water molecules” models. This model has been printed successfully using these parameters on Shapeways’ laser sintering printer in the following material: Processed Versatile Plastic (Strong & Flexible Plastic)