13 research outputs found

    Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development

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    PLANNED INCAPACITY TO SUCCEED? POLICY-MAKING STRUCTURE AND POLICY FAILURE

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    Policies may fail in two analytically distinct ways: they may fail to achieve their goals, or they may fail to retain political support and be terminated. By failing to distinguish between ineffectiveness and political failure, the three most common interpretations of the War on Poverty and the Comprehensive Employment and Training Act (failure owing to central government incompetence, failure owing to pluralism, and "hidden" success) cannot adequately account for the gap between their ambiguous performance and their clear political failure. To understand these differences, one must understand the effect of America's fragmented political structure on the design and implementation of poverty and unemployment remedies. Under resource constraints and given a large degree of policy discretion, American states in the aggregate have retained their historic resistance to social policies that would increase short-term expenditures and reduce the attractiveness of their business climate. These jurisdictions and their Congressional representatives opposed new fully nationalized initiatives, insisting on policy designs that promised fiscal relief while protecting state and local policy control. National policymakers found that grant-in-aid programs offered the path of least resistance in these circumstances. Although social policy grant programs could win initial approval in Congress, these designs proved to be increasingly unwieldy, expensive, and difficult to control in practice. The programs yielded ambiguous overall results but provided unambiguous examples of waste, fraud and abuse, fueling the perception of failure and contributing to the backlash against these programs and their political failure. Copyright 1988 by The Policy Studies Organization.

    State of the Climate in 2012

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    International audienceEditors note: For easy download the posted pdf of the State of the Climate for 2012 is a very low-resolution file. A high-resolution copy of the report is available by clicking here. Please be patient as it may take a few minutes for the high-resolution file to download

    Delivery Systems for in Vivo use of Nucleic Acid Drugs

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    Adult Neurogenesis and Central Nervous System Cell Cycle Analysis

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    Initial Preparation for Primary School Teaching: Becoming a Teacher

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