September 11: Symbolism And Responses To 9/11

Professors Hopkins and Hopkins review the impact of 9/11 as a symbol in American politics. Following the terrorist attacks, 9/11 became a simple reference condensing wide-ranging events and emotions. Various interpretations emerged about what caused 9/11 and enabled the attacks. The authors claim that 9/11 allowed US leaders to pursue certain policy prescriptions that otherwise would have been blocked. Among four possible prescriptions for responding to the attacks, the Bush administration chose a praetorian policy of preventive war, with Iraq as its first example. In the authors’ view, by pursuing an expansive but highly militarized response, the US has overlooked the need to alleviate the conditions that made 9/11 possible. The authors recommend that the US, as part of a multilateral effort, allocate major resources to expanding global public goods, including measures that strengthen barriers to proliferation, enhance fighting of global crime, and reduce incentives for terrorism, especially ones arising in failing states where distorted education and weak protection of human rights encourage organized terrorism

Mechanisms of interpersonal sway synchrony and stability

Here we explain the neural and mechanical mechanisms responsible for synchronizing sway and improving postural control during physical contact with another standing person. Postural control processes were modelled using an inverted pendulum under continuous feedback control. Interpersonal interactions were simulated either by coupling the sensory feedback loops or by physically coupling the pendulums with a damped spring. These simulations precisely recreated the timing and magnitude of sway interactions observed empirically. Effects of firmly grasping another person's shoulder were explained entirely by the mechanical linkage. This contrasted with light touch and/or visual contact, which were explained by a sensory weighting phenomenon; each person's estimate of upright was based on a weighted combination of veridical sensory feedback combined with a small contribution from their partner. Under these circumstances, the model predicted reductions in sway even without the need to distinguish between self and partner motion. Our findings explain the seemingly paradoxical observation that touching a swaying person can improve postural control.This work was supported by two BBSRC grants (BB/100579X/1 and an Industry Interchange Award)

The effect of rotation and tidal heating on the thermal lightcurves of Super Mercuries

Short period (<50 days) low-mass (<10Mearth) exoplanets are abundant and the few of them whose radius and mass have been measured already reveal a diversity in composition. Some of these exoplanets are found on eccentric orbits and are subjected to strong tides affecting their rotation and resulting in significant tidal heating. Within this population, some planets are likely to be depleted in volatiles and have no atmosphere. We model the thermal emission of these "Super Mercuries" to study the signatures of rotation and tidal dissipation on their infrared light curve. We compute the time-dependent temperature map at the surface and in the subsurface of the planet and the resulting disk-integrated emission spectrum received by a distant observer for any observation geometry. We calculate the illumination of the planetary surface for any Keplerian orbit and rotation. We include the internal tidal heat flow, vertical heat diffusion in the subsurface and generate synthetic light curves. We show that the different rotation periods predicted by tidal models (spin-orbit resonances, pseudo-synchronization) produce different photometric signatures, which are observable provided that the thermal inertia of the surface is high, like that of solid or melted rocks (but not regolith). Tidal dissipation can also directly affect the light curves and make the inference of the rotation more difficult or easier depending on the existence of hot spots on the surface. Infrared light curve measurement with the James Webb Space Telescope and EChO can be used to infer exoplanets' rotation periods and dissipation rates and thus to test tidal models. This data will also constrain the nature of the (sub)surface by constraining the thermal inertia.Comment: 15 pages, 13 figures, accepted for publication in Astronomy & Astrophysic

Slippery runs, shifty stops, backward steps and forward hops: -2, -1, +1, +2, +5 and +6 Ribosomal frameshifting

Journal ArticleFrameshift mutations frequently express residual levels of gene activity; that is, they are often leaky. This leakiness can be used as a tool to define the functional components that affect the reading frame during gene expression. Recent technological advances in the capability to efficiently build synthetic DNA sequences have facilitated the construction of small, defined "frameshift windows." These windows are regions where frameshift events can be detected and measured. The cloned synthetic window is fused onto th 5' coding region of an active B-galactosidase gene that provides a sensitive monitor for the frameshift events. Fusions onto the lac Z gene have the advantages of simple colorimetric assays for B-galactosidase activity and little or no effect of the fused sequence on the specific activity or stability of the enzyme. A frameshift event also leaves a clue to its character in the protein sequence translated from the window's m-RNA sequence. Recovery of the frameshift containing B-galactosidase in sufficient yield and purity for determining its amino-terminal sequence provides hard evidence for the occurrence of a frameshift, and this sequence may be used to infer the kind of event generating the loss of reading frame

On composite systems of dilute and dense couplings

Composite systems, where couplings are of two types, a combination of strong dilute and weak dense couplings of Ising spins, are examined through the replica method. The dilute and dense parts are considered to have independent canonical disordered or uniform bond distributions; mixing the models by variation of a parameter $\gamma$ alongside inverse temperature $\beta$ we analyse the respective thermodynamic solutions. We describe the variation in high temperature transitions as mixing occurs; in the vicinity of these transitions we exactly analyse the competing effects of the dense and sparse models. By using the replica symmetric ansatz and population dynamics we described the low temperature behaviour of mixed systems.Comment: 35 pages, 9 figures, submitted to JPhys

Image-based Quantification of 3D Morphology for Bifurcations in the Left Coronary Artery: Application to Stent Design

Background Improved strategies for stent‐based treatment of coronary artery disease at bifurcations require a greater understanding of artery morphology. Objective We developed a workflow to quantify morphology in the left main coronary (LMCA), left anterior descending (LAD), and left circumflex (LCX) artery bifurcations. Methods Computational models of each bifurcation were created for 55 patients using computed tomography images in 3D segmentation software. Metrics including cross‐sectional area, length, eccentricity, taper, curvature, planarity, branching law parameters, and bifurcation angles were assessed using open‐sources software and custom applications. Geometric characterization was performed by comparison of means, correlation, and linear discriminant analysis (LDA). Results Differences between metrics suggest dedicated or multistent approaches should be tailored for each bifurcation. For example, the side branch of the LCX (i.e., obtuse marginal; OM) was longer than that of the LMCA (i.e., LCXprox) and LAD (i.e., first diagonal; D1). Bifurcation metrics for some locations (e.g., LMCA Finet ratio) provide results and confidence intervals agreeing with prior findings, while revised metric values are presented for others (e.g., LAD and LCX). LDA revealed several metrics that differentiate between artery locations (e.g., LMCA vs. D1, LMCA vs. OM, LADprox vs. D1, and LCXprox vs. D1). Conclusions These results provide a foundation for elucidating common parameters from healthy coronary arteries and could be leveraged in the future for treating diseased arteries. Collectively the current results may ultimately be used for design iterations that improve outcomes following implantation of future dedicated bifurcation stents

Effects of Buoyancy on Laminar, Transitional, and Turbulent Gas Jet Diffusion Flames

Gas jet diffusion flames have been a subject of research for many years. However, a better understanding of the physical and chemical phenomena occurring in these flames is still needed, and, while the effects of gravity on the burning process have been observed, the basic mechanisms responsible for these changes have yet to be determined. The fundamental mechanisms that control the combustion process are in general coupled and quite complicated. These include mixing, radiation, kinetics, soot formation and disposition, inertia, diffusion, and viscous effects. In order to understand the mechanisms controlling a fire, laboratory-scale laminar and turbulent gas-jet diffusion flames have been extensively studied, which have provided important information in relation to the physico-chemical processes occurring in flames. However, turbulent flames are not fully understood and their understanding requires more fundamental studies of laminar diffusion flames in which the interplay of transport phenomena and chemical kinetics is more tractable. But even this basic, relatively simple flame is not completely characterized in relation to soot formation, radiation, diffusion, and kinetics. Therefore, gaining an understanding of laminar flames is essential to the understanding of turbulent flames, and particularly fires, in which the same basic phenomena occur. In order to improve and verify the theoretical models essential to the interpretation of data, the complexity and degree of coupling of the controlling mechanisms must be reduced. If gravity is isolated, the complication of buoyancy-induced convection would be removed from the problem. In addition, buoyant convection in normal gravity masks the effects of other controlling parameters on the flame. Therefore, the combination of normal-gravity and microgravity data would provide the information, both theoretical and experimental, to improve our understanding of diffusion flames in general, and the effects of gravity on the burning process in particular

Unification via intermediate symmetry breaking scales with the quartification gauge group

The idea of quark-lepton universality at high energies has been introduced as a natural extension to the standard model. This is achieved by endowing leptons with new degrees of freedom -- leptonic colour, an analogue of the familiar quark colour. Grand and partially unified models which utilise this new gauge symmetry SU(3)_\ell have been proposed in the context of the quartification gauge group SU(3)^4. Phenomenologically successful gauge coupling constant unification without supersymmetry has been demonstrated for cases where the symmetry breaking leaves a residual SU(2)_\ell unbroken. Though attractive, these schemes either incorporate ad hoc discrete symmetries and non-renormalisable mass terms, or achieve only partial unification. We show that grand unified models can be constructed where the quartification group can be broken fully [i.e. no residual SU(2)_\ell] to the standard model gauge group without requiring additional discrete symmetries or higher dimension operators. These models also automatically have suppressed nonzero neutrino masses. We perform a systematic analysis of the renormalisation-group equations for all possible symmetry breaking routes from SU(3)^4 --> SU(3)_q x SU(2)_L x U(1)_Y. This analysis indicates that gauge coupling unification can be achieved for several different symmetry breaking patterns and we outline the requirements that each gives on the unification scale. We also show that the unification scenarios of those models which leave a residual SU(2)_\ell symmetry are not unique. In both symmetry breaking cases, some of the scenarios require new physics at the TeV scale, while others do not allow for new TeV phenomenology in the fermionic sector.Comment: 25 page

Faying Surface Lubrication Effects on Nut Factors

Bolted joint analysis typically is performed using nut factors derived from textbooks and procedures from program requirement documents. Joint specific testing was performed for a critical International Space Station (ISS) joint. Test results indicate that for some configurations the nut factor may be significantly different than accepted textbook values. This paper presents results of joint specific testing to aid in determining if joint specific testing should be performed to insure required preloads are obtained