PERAN MAHASISWA DALAM PENDIDIKAN DAN PEMBENTUKAN KARAKTER PEDULI LINGKUNGAN PADA ANAK-ANAK

Penyabaran covid-19 telah membawa dampak bagi segala bidang tidak terkecuali bidang pendidikan, dengan adanya penyebaran covid-19 sistem pembelajaran berubah menjadi daring. Setelah sistem ini dijalankan terdapat beberapa permasalahan yang terjadi seperti minat berlajar yang mulai menurun. Awal tahun 2022 dimana kasus Covid 19 mengalami penurunan drastis. Setelah penurunan ini kebijakan pembelajaran berubah menjadi tatap muka, setelah lama menggunakan sistem daring terdapat beberapa kendala yang dialami para murid seperti mereka harus mulai beradaptasi lagi dengan sistem luring. Metode yang menurut kelompok KKN 41 UPN Vetaran Jawa Timur merupakan metode demontrasi. Bentuk kegiatan program taman belajar ini adalah mengajar di balai RT, kelompok KKN 41 menciptakan lingkungan kelas yang nyaman, memberikan hadiah,  mengakrabkan diri , membuat beberapa games dan pembelajaran bertanam vertikultur

A systematic review of optical coherence tomography findings in adults with mild traumatic brain injury

Mild traumatic brain injury (mTBI) is common with many patients suffering disabling long-term sequelae, with visual symptoms frequently reported. There are no objective biomarkers of mTBI that are routinely used in clinical practice. Optical coherence tomography (OCT) has been used in mTBI research, as it enables visualisation of the neuroretina, allowing measurement of the retinal nerve fibre layer and ganglion cell layer. This systematic review aims to appraise the available literature and assess whether there are significant changes within the retinal nerve fibre layer and ganglion cell layer in subjects after mTBI. A systematic review was carried out in accordance with PRISMA guidelines and registered with PROSPERO (Number: CRD42022360498). Four databases were searched for relevant literature published from inception until 1 September 2022. Abstracts and full texts were screened by three independent reviewers. Initial screening of databases yielded 341 publications, of these, three fulfilled all the criteria for inclusion. All three studies showed thinning of the retinal nerve fibre layer, whereas there were no significant changes in the ganglion cell layer. This systematic review demonstrated that thinning of the retinal nerve fibre layer (but not of the ganglion cell layer) is associated with mTBI. It provides preliminary evidence for the use of the retinal nerve fibre layer as a potential biomarker of damage to the visual system in mTBI. Further prospective longitudinal studies ensuring uniform diagnosis and accurate phenotyping of mTBI are needed to understand the effects on the visual system and potential of OCT as a prognostic biomarker

(<i>R</i>)‑DM-SEGPHOS–Ag(I)-Catalyzed Enantioselective Synthesis of Pyrrolidines and Pyrrolizidines via (1,3)- and Double (1,3)-Dipolar Cycloaddition Reactions

An efficient diastereo- and enantioselective route to access a wide range of highly substituted pyrrolidine and pyrrolizidine derivatives has been described via (1,3)- and double (1,3)-dipolar cycloaddition reactions catalyzed by the (<i>R</i>)-DM-SEGPHOS–Ag­(I) complex. The reactions proceed smoothly at ambient temperature, affording a variety of pyrrolidines and pyrrolizidines in high yields (up to 93%) with up to 99:1 dr and excellent enantioselectivities (up to 98% ee) without any additives. The newly synthesized pyrrolidine and pyrrolizidine derivatives contain four and seven contiguous stereogenic centers, respectively. Moreover, the synthetic utility of enantioenriched products has been demonstrated by transforming them into various synthetically useful advanced intermediates