ELECTROCHEMICAL STUDIES OF PARACETAMOL ON POLYANILINE-SILVER NANOSTRUCTURAL THIN FILMS MODIFIED GLASSY CARBON ELECTRODE

Analysis of biomolecule of paracetamol through stripping voltammetric determination procedure on polyaniline-silver thin films modified glassy carbon electrode. The effect of pH was studied at different pH media such as 1.0 to pH 13.0. The voltammetric investigation of paracetamol was carried out from −0.2 V to 1.2 V versus Ag/AgCl using modified glassy carbon (GC) as working electrode. The electroanalytical determination parameters are highly dependent on their configuration and on the dimensions of the working carbon electrode. The cyclic voltammogram exhibited one oxidation and one reduction peak. Peak current dependence on the scan rate is studied by varying the scan rate from 25 to 500 mv/s at concentration 300 ppm. The best limit of detection obtained for paracetamol was 10 ppb and the linear range from 100 to 600 ppb on GCE configuration. The biosensors were successfully applied for the detection of paracetamol in several drug formulations

Surfactant-mediated and morphology-controlled nanostructured LiFePO4/carbon composite as a promising cathode material for Li-ion batteries

The synthesis of morphology-controlled carbon-coated nanostructured LiFePO4 (LFP/Carbon) cathode materials by surfactant-assisted hydrothermal method using block copolymers is reported. The resulting nanocrystalline high surface area materials were coated with carbon and designated as LFP/C123 and LFP/C311. All the materials were systematically characterized by various analytical, spectroscopic and imaging techniques. The reverse structure of the surfactant Pluronic® 31R1 (PPO-PEO-PPO) in comparison to Pluronic® P123 (PEO-PPO-PEO) played a vital role in controlling the particle size and morphology which in turn ameliorate the electrochemical performance in terms of reversible specific capacity (163 mAhg 1 and 140 mAhg 1 at 0.1 C for LFP/C311 and LFP/ C123, respectively). In addition, LFP/C311 demonstrated excellent electrochemical performance including lower charge transfer resistance (146.3 Ω) and excellent cycling stability (95% capacity retention at 1 C after 100 cycles) and high rate capability (163.2 mAhg 1 at 0.1 C; 147.1 mAhg 1 at 1 C). The better performance of the former is attributed to LFP nanoparticles (< 50 nm) with a specific spindle-shaped morphology. Further, we have also evaluated the electrode performance with the use of both PVDF and CMC binders employed for the electrode fabrication

Infrared Thermography for the Ante Mortem Detection of Bruising in Horses Following Transport to a Slaughter Plant

Undetected injury of horses sustained during road transport to slaughter is a welfare concern. This study evaluated digital infrared thermography (DT) for the detection of ante-mortem bruising in horses following transport to a slaughter plant. The sensitivity and specificity of DT for the detection of bruises following transport was evaluated. DT images were obtained from 93 horses (2–3 horses per load; 40 loads) at a Canadian federally approved slaughter plant. From an elevated platform 5 m from the horses, left and right lateral DT images, and one caudal pelvic area image were obtained from each horse. After slaughter the carcasses were examined for bruising (a visually discolored area on the carcass caused by damage to the blood vessels) and findings documented. Sensitivity, specificity, and predictive values were calculated for DT assessment of bruising. The prevalence of bruising on post mortem inspection was 54%. The DT approach to bruise detection at the region of interest level of 93 horses (n = 186 sides) resulted in a sensitivity of 42% and specificity of 79%. As the sensitivity was low, a more sensitive DT camera and allowing for a longer equilibration time for horses after transport may improve this approach to post transport assessment of subclinical injury

Synthesis and characterization of <img src='/image/spc_char/micro.gif' border=0>-phenoxo-bridged binuclear copper(II) complexes derived from binucleating ligands

29-34The new pentadentate binucleating symmetrical ligand 2,6-bis [N-(3,5-dichloro-2-hydroxybenzyl)-N-cyclohexylamino-methyl]-4-methylphenol (H3L1) has been prepared and its binuclear copper(II) complexes of the general formula [Cu2L(X)], where X = OH (perchlorato counter ion complexes), OAc, NO3 have been prepared. Their spectral properties and catecholase activities were studied. New unsymmetrical ligands and their complexes have also been synthesized. The phenolate oxygen atom of the binucleating ligands behaves as a bridging group. Conductivity studies showed that all the complexes are neutral. ESR spectra of the complexes show a broad band centred at 3500 G with no hyperfine splittings. The observed room temperature magnetic studies were found to be less than spin only value for d9 system. The rate constants of the complexes for the oxidation of catechol to o-quinone were in the range of 0.7210-3 to 15.010-3 min-1

Layer Router for Grayscale Stego - A Hardware Architecture on FPGA and ASIC Platforms

701-703In the present era of secret communication, steganography has obtained a significant place in information security by means of offering variety of techniques for cleverly hiding the information. In addition to the existing hardware stego algorithms, an adaptive block hardware stego system has been proposed in this paper which follows a shortest path algorithm for performing secret concealment in grayscale images. The proposed image steganographic hardware architecture which adopts traversal procedures predominant in area routing has been implemented both in Stratix III FPGA as well as ASIC Platforms

Quantification of Zonula Occludens-1 mRNA expression in cultu-red bovine retinal endothelial cells, using SYBR green real-time PCR

A simple and rapid real-time reverse transcription-PCR (RT-PCR) technique using SYBR green fluorescence was developed to quantify Zonula Occludens-1 (ZO-1) mRNA expression in histamine-treated cultured bovine retinal microvessel endothelial cells. There was no difference between the quantity of ZO-1 mRNA expression in histamine-treated (10-7M to 10-9 M) and untreated bovine retinal endothelial cells at high magnesium levels. Immunohisto-chemistry staining and western blot assay unequivocally demonstrated the approximately similar levels of ZO-1 protein in both histamine-treated and non-treated endothelial cells at high magnesium concentrations

Metabolic Syndrome—An Emerging Constellation of Risk Factors: Electrochemical Detection Strategies

Metabolic syndrome is a condition that results from dysfunction of different metabolic pathways leading to increased risk of disorders such as hyperglycemia, atherosclerosis, cardiovascular diseases, cancer, neurodegenerative disorders etc. As this condition cannot be diagnosed based on a single marker, multiple markers need to be detected and quantified to assess the risk facing an individual of metabolic syndrome. In this context, chemical- and bio-sensors capable of detecting multiple analytes may provide an appropriate diagnostic strategy. Research in this field has resulted in the evolution of sensors from the first generation to a fourth generation of &lsquo;smart&rsquo; sensors. A shift in the sensing paradigm involving the sensing element and transduction strategy has also resulted in remarkable advancements in biomedical diagnostics particularly in terms of higher sensitivity and selectivity towards analyte molecule and rapid response time. This review encapsulates the significant advancements reported so far in the field of sensors developed for biomarkers of metabolic syndrome