Calculation of AGARD Wing 445.6 Flutter Using Navier-Stokes Aerodynamics

An unsteady, 3D, implicit upwind Euler/Navier-Stokes algorithm is here used to compute the flutter characteristics of Wing 445.6, the AGARD standard aeroelastic configuration for dynamic response, with a view to the discrepancy between Euler characteristics and experimental data. Attention is given to effects of fluid viscosity, structural damping, and number of structural model nodes. The flutter characteristics of the wing are determined using these unsteady generalized aerodynamic forces in a traditional V-g analysis. The V-g analysis indicates that fluid viscosity has a significant effect on the supersonic flutter boundary for this wing

Contextual cueing of visual search is associated with greater subjective experience of the search display configuration

Visual search is facilitated when display configurations are repeated over time, showing that memory of spatio-configural context can cue the location of the target. The present study investigates whether memory of the search target in relation to the configuration of distractors alters subjective experience of the visual search target and/or the subjective experience of the display configuration. Observers performed a masked localization task for targets embedded in repeated vs. non-repeated (baseline) arrays of distractors items. After the localization response, observers reported their subjective experience of either the target or the display configuration. Bayesian analysis revealed that repeated displays resulted in a stronger visual experience of both targets and display configurations. However, subsequent analysis showed that repeated search displays increased the correlation between the experience of the display configuration and localization accuracy, but there was no such effect on experience of the target stimulus. We suggest that memory of visual context enhances the representation of the current visual search display. This representation improves visual search and at the same time increases observers’ subjective experience of the display configuration

Electrocerebral Recovery During the Intracarotid Amobarbital Procedure: Influence of Interval Between Injections

Purpose and Methods : During the intracarotid amobarbital procedure (IAP) at the University of Michigan, continuous scalp EEG monitoring guides the timing for presentation of memory items and postinjection testing. Most of our patients have undergone bilateral injections. The interval between injections varied from 22 to 60 min, depending on the test and recovery time, as well as the time to catheterize the second side. After noting a trend toward prolonged electro-graphic recovery following the second injection, we tested our clinical impression that recovery of the second hemisphere may be influenced by (a) the time between injections and (b) which hemisphere is injected first (epileptogenic or nonepileptogenic). To study these questions, we analyzed EEG recovery data from 48 consecutive IAPs. Approximately half the patients had the epileptogenic side injected first. Results : We found that (a) electrographic recovery after the second injection is prolonged if the interval between bilateral injections is less than 40 minutes and (b) electrographic recovery is more rapid after injection of the epileptogenic hemisphere. Conclusions : We now recommend waiting at least 45 min between injections. The pathophysiology of more prolonged amobarbital effect on the nonepileptogenic hemisphere than on the epileptogenic hemisphere remains unclear.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65275/1/j.1528-1157.1997.tb00067.x.pd

Toxicology Studies of Lewisite and Sulfur Mustard Agents: Genetic Toxicity of Lewisite (L) In Chinese Hamster Ovary Cells

The cytotoxic clastogenic and mutagenic effects of the arsenic containing vesicant, Lewisite (L) [dichloro(2-chlorovinyl) arsine], have been investigated using Chinese hamster ovary cells. One hour exposures to Lewisite were cytotoxic in uM amounts. The cell survival response yields a D37 of 0.6 uM and an extrapolation number of 2.5. The mutagenic response at the hypoxantnine-guanine phosporibosyl transferase (HGPRT) locus was sporadic and not significantly greater than control values when cells were exposed over a range of 0.125 to2.0 uM. Sister chromatid exchange (SCE) induction, a measure of chromosomal rearrangement, was weakly positive over a range of 0.25 to 1.0 uM but the values were not significantly greater than the control response. Chromosomal aberrations were induced at 0.75 and 1.0 UMin one experiment and 0.5 and 0.75 uM in another experiment. The Induced values were significantly greater than the control values. Lewisite appears to be cytotoxic and clastogenic in our investigations but SCE and mutation at the HGPRT locus are not significantly greater than control values. Lewisita toxicity was in some ways similar to radiomimetic chemicals such as bleomycin

Toxicology Studies on Lewisite and Sulfur Mustard Agents: Genetic Toxicity of Sulfur Mustard (HD) in Chinese Hamster Ovary Cells Final Report

The cytotoxic, clastogenic and mutagenic effects of sulfur nustard in Chinese hamster ovary cells are described in this reoort. The cytotoxicity data indicate that micromolar amounts of HC are highly toxic in microrolar amounts. Chromosone aberration frequencies increased in a dose-dependent manner over a dose range of 0. 5 to 1.0 {micro}m and SCE increased in a dose-dependent fashion in the dose range of 0.0625 to 0.25 {micro}M. Mutation induction at the HGPRT locus was sporadic, but the majority of the exoosures resulted in mutation frequencies which were 1.2 to 4.3 fold higher than the spontaneous frequencies

Toxicology Studies on Lewisite and Sulfur Mustard Agents: Genetic Toxicity of Sulfur Mustard (HD) in Chinese Hamster Ovary Cells Final Report

The cytotoxic, clastogenic and mutagenic effects of sulfur nustard in Chinese hamster ovary cells are described in this reoort. The cytotoxicity data indicate that micromolar amounts of HC are highly toxic in microrolar amounts. Chromosone aberration frequencies increased in a dose-dependent manner over a dose range of 0. 5 to 1.0 {micro}m and SCE increased in a dose-dependent fashion in the dose range of 0.0625 to 0.25 {micro}M. Mutation induction at the HGPRT locus was sporadic, but the majority of the exoosures resulted in mutation frequencies which were 1.2 to 4.3 fold higher than the spontaneous frequencies

Archimedean-like colloidal tilings on substrates with decagonal and tetradecagonal symmetry

Two-dimensional colloidal suspensions subject to laser interference patterns with decagonal symmetry can form an Archimedean-like tiling phase where rows of squares and triangles order aperiodically along one direction [J. Mikhael et al., Nature 454, 501 (2008)]. In experiments as well as in Monte-Carlo and Brownian dynamics simulations, we identify a similar phase when the laser field possesses tetradecagonal symmetry. We characterize the structure of both Archimedean-like tilings in detail and point out how the tilings differ from each other. Furthermore, we also estimate specific particle densities where the Archimedean-like tiling phases occur. Finally, using Brownian dynamics simulations we demonstrate how phasonic distortions of the decagonal laser field influence the Archimedean-like tiling. In particular, the domain size of the tiling can be enlarged by phasonic drifts and constant gradients in the phasonic displacement. We demonstrate that the latter occurs when the interfering laser beams are not adjusted properly

High resolution observations of SiO masers: comparing the spatial distribution at 43 and 86 GHz

We present sub-milliarcsecond observations of SiO masers in the late-type stars IRC +10011 and Chi Cyg. We have used the NRAO Very Long Baseline Array (VLBA) to map the 43 GHz (v=1, 2 J=1-0) and the 86 GHz (v=1, 2 J=2-1) SiO masers. All the transitions have been imaged except the v=2 J=2-1 in IRC +10011. We report the first VLBI map of the v=1 J=2-1 28SiO maser in IRC +10011 as well as the first VLBA images of SiO masers in an S-type Mira variable, Chi Cyg. In this paper we have focused on the study of the relative spatial distribution of the different observed lines. We have found that in some cases the observational results are not reproduced by the current theoretical pumping models, either radiative or collisional. In particular, for IRC +10011, the v=1 J=1-0 and J=2-1 28SiO lines have different spatial distributions and emitting region sizes, the J=2-1 emission being located in an outer region of the envelope. For Chi Cyg, the distributions also differ, but the sizes of the masing regions are comparable. We suggest that the line overlaps between ro-vibrational transitions of two abundant molecular species, H2O and 28SiO, is a possible explanation for the discrepancies found between the observations and the theoretical predictions. We have introduced this overlapping process in the calculations of the excitation of the SiO molecule. We conclude that the line overlaps can strongly affect the excitation of SiO and may reproduce the unexpected observational results for the two sources studied.Comment: 16 pages, 12 figure