Effect of Insecticides (Pyrethroids) on Eosinophil Count in School Children

Background: Study was conducted in school children to reveal the toxic effects of pyrethroids which causes allergic reactions with in the body especially altered lung function tests and eosinophil count. Objective: In the present study, the effects of pyrethroids on eosinophil count of school children were analyzed.Methodology: The present study is a cross-sectional analytical study. The study was conducted at Government Girls Primary School, Sita Nagar, Karachi including 50 children with ages between 6 – 10 years. They were divided equally into two groups: group A (exposed to insecticidal spray) and group B (exposed to mosquito coil). The correlations between the insecticides (Pyrethroids), and eosinophil by linear regression analysis confirmed that insecticides (Pyrethroids) had a strong correlation with the eosinophil count under study exemplified by the significant increase in Eosinophil count was observed after exposure to mosquito coil whereas there was no association between insecticidal spray and Eosinophil count. Results: There was significant increase in Eosinophil count after exposure to mosquito coil whereas no association was observed between insecticidal spray and Eosinophil count.Conclusions: The use of spray over the coil is less hazardous to the health

A mild and selective method for the conversion of nitroalkanes to carbonyl compounds

Nef reaction is one of the most commonly used method for the conversion of nitroalkanes to carbnyl coacpunds. It was found that the salt of primary nitroparaffins are transformed in to aldehydes and those of secondary nitro coapounda into ketones, when they are treated with aqueous acid. Ernate procedures for effecting this transformation have been reported. Cedures appeared in the literature after the work of Sehecter and Williams using potassium penaanganate as the axidant. Recently, Kornblum and Steliou reported useful modif icationa of the original permanganate proeedtlre. A number of modifications and alt In fact most of the modified pro- Although the yield of the carbony1 compounds is generally high i n simple nitroalkanes Using the modi-fied permanganate procedures, the yield drops down considerably in the case of substrates containing other oxidizable functional groups like carbon-carbon double bonds and hydroxyl groups. Hence a need still exists for the development of a methodology which is mild and more selective

Diabetic Neuropathy And Its Correlation With Vitamin D3

oai:ojs2.biosight.org:article/1The purpose of this study was to determine neurotransmitter and vitamin D3 levels in both men and women. Fifty healthy middle-aged men and women of 41.17 ± 9.6 and 42 ± 9.59 years respectively were selected. They have no known disease. While 50 male and female diabetic patients with an average age of 55.5 ± 14.92 and 47.87 ± 10.81 years were selected respectively. Anthropological data, including age, weight and length, were recorded in both controls and patients. To test the hypothesis of study relationship between vitamin D and neurotransmitters was analyzed in both groups. The statistical significance was taken at the p-level <0.05. The diabetic patients had neuropathy for 3 to 5 years with high HbA1c. Age and gender do not significantly affect neuropathy in diabetes. The average standard deviation of vitamin D3 is significantly lower in those having diabetic neuropathies, 12,448 ± 3,519 ng / ml (SD), which is not 24,958 ± 5,419 ng / ml, and was compared with vitamin D3 neuropathy in patients who did not have diabetes. (p <0.01). This analysis has shown that the neuropathy of diabetes is strongly linked to vitamin D3 after including confusion such as "Duration of diabetes and HbA1c". In patients with diabetes, the effects of vitamin D3 on neuropathy and the need for further studies ensure that there is a delay in preventing the dose of vitamin D3 or in the onset of neuropathy due to diabete

Effect of Insecticides (Pyrethroids) on Eosinophil Count in School Children

Background: Study was conducted in school children to reveal the toxic effects of pyrethroids which causes allergic reactions with in the body especially altered lung function tests and eosinophil count. Objective: In the present study, the effects of pyrethroids on eosinophil count of school children were analyzed.Methodology: The present study is a cross-sectional analytical study. The study was conducted at Government Girls Primary School, Sita Nagar, Karachi including 50 children with ages between 6 – 10 years. They were divided equally into two groups: group A (exposed to insecticidal spray) and group B (exposed to mosquito coil). The correlations between the insecticides (Pyrethroids), and eosinophil by linear regression analysis confirmed that insecticides (Pyrethroids) had a strong correlation with the eosinophil count under study exemplified by the significant increase in Eosinophil count was observed after exposure to mosquito coil whereas there was no association between insecticidal spray and Eosinophil count. Results: There was significant increase in Eosinophil count after exposure to mosquito coil whereas no association was observed between insecticidal spray and Eosinophil count.Conclusions: The use of spray over the coil is less hazardous to the health

A mild and highly selective method for the regeneration of carbonyl compounds from oximes and (2,4-dinitrophenyl)hydrazones

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Comparison Of Lung Function Tests Between Healthy And Asthmatic Individuals: Comparison of Pulmonary Functions Tests

Background: Comparison of pulmonary function tests (PFTs) were achieved between asthmatic case and Controls. Materials & Methods: Case-control study conducted at Baqai Medical University (50 cases and 50 control). PFTs in both the participants were estimated by spirometry; FEC, FEV1 and their ratios were estimated. Results: According to the findings all spirometric values were lower in asthmatic patients as compared to healthy subjects. Moreover the asthamatic subjects had lower lung values when compared with healthy subjects. Conclusion: The current study evaluated spirometric values in asthmatic patients in Gadap area. This study's findings can be applied to the treatment of asthma in people of all ages