Ectopic pregnancy and unsupervised abortion pills: the hidden truth

Background: Aim of the study was the indiscriminate use of self-consumption of abortion pills and its association with complication like ectopic pregnancy reporting to a tertiary care center.Methods: The study was a prospective observational study conducted in the department of obstetrics and gynecology, Kamla Nehru State hospital for mother and child, Indira Gandhi medical college Shimla w.e.f. 1st July 2018 to 30th June 2019. A total of 27 women reported to the hospital who were diagnosed of having ectopic pregnancy after intake of abortion pills.Results: A total of 27 cases presented to the hospital who were diagnosed to have ectopic pregnancy. Maximum 18 (67%) cases were in 21-30 years of age group. Married women constituted 21 (77%) cases. The 14 (52%) belonged to rural area while 13 (48%) belonged to urban area. The chemist was found to be source of procurement in 19 (70%) cases, private practitioner in 6 (22%) cases and only two consumed pills after consultation with registered doctor.Conclusions: This study shows urgent need for legislation and restriction of drugs used for medical termination of pregnancy. Drugs should be made available via health care facilities under supervision to reduce maternal mortality and morbidity due to indiscriminate use of these pills.

Long PFN in unstable subtrochantric fracture with absent lateral wall support in proximal fragment with delayed augmentation with encircalage wire and bone grafting

In 1949 Boyd and Griffin Subtrochanteric fracture femur as a variant of peritrochanteric fracture with higher incidence of unsatisfactory result both in the elderly and young. Most of this fracture is with higher incidence of unsatisfactory result after operative treatment This single case study shows one of the unpredicted iotrogenic complications. Material and method: Patient is 78yr female patient with multiple co-morbid conditions with subtrochanetric fracture. Surgery was done with long PFN nail  inserted with good purchase in head, reduction check under C-arm with  in antero-posterior & lateral  view shows little malreduction and nail  is out of medulary cavity in proximal fragment. Revision in same sitting not possible due to some medical reasons. Revision surgery done after fitness and reduction held with encieclage wire and bone grafting done. Conclusion: Even without lateral wall support if there is good purchase of screws in head and shaft, there will be good union and good functional outcome

THE STUDY OF NUTRITIONAL REQUIREMENTS IN SECOND TRIMESTER W.S.R. GARBHINI PARICHARYA ACCORDING TO SUSHRUTACHARYA

It is the need of an hour to have healthy pregnancies in Indian population as the normal nutritional requirements in maternal periods of women in India are not getting fulfilled, so as the malnourished and birth defective children are born. Out of three trimesters of pregnancy in second trimester nutrition need are higher than estimated nutrition requirement for non pregnant women which is less in first trimester. As per the modern science there are lot many nutritional deficiencies occurring in second trimester which causes serious health hazards in mother as well in fetus. The main deficiencies in second trimester of pregnancy are protein, folic acid, calcium, iron, vitamin D, thiamine, vitamin A.Ancient Ayurveda prescribes some set of guidelines which can help make this time more easy for the women. Ayurveda has given proper regimens of diet and life style in during different stages of pregnancy. This paper talks about second trimester of pregnancy because in this all organ starts to appear according to Ayurvedic Samhitas and modern aspects also. It is given in Mansanumasik Garbhini Paricharya which is mentioned in Ayurvedic Samhita, the regime for the pregnant women. It is similar to the modern science diet to the pregnant women. Therefore this is a small effort to find out the exact concept of Garbhini Paricharya given by Aacharya sushruta is nutritionally a complete supplement for Garbhini

STUDY OF MARMAS IN LOWER EXTREMITY WITH SPECIAL REFERENCE TO URVI MARMA

Marma (vital point) science is one element of Ayurveda gifted by Acharyas. It is not much developed in modern science. Marma are vital point on body surface having importance regarding traumatic effect. Marma is vital point where injury occur can lead to disability, dysfunctioning or even termination of life. Every aspect of Marma like definition, signs symptoms of Marma injury was thoroughly explained by Acharya Sushrut. Not only the Marma but also the Marma Viddha Lakashana (after effect injury) was documented by Acharya Sushrut. These Lakshanas (symptoms) shows similarity with the sign & symptoms occur due to the trauma at that site. It is an need of an hour to find out the exact structure present at Marma site so as to prevent disability or deformity effect after injury. Here we are studying Urvi Marma, which lies in the middle of the thigh as given in Samhita Granthas. As per modern anatomy in the middle region of thigh, there is structure of adductor canal. Adductor canal contains femoral artery, femoral vein, which are major blood vessels of lower limb. Urvi Marma which has been described as Sira Marma (vascular vital point) & Vaikalyakara Marma (deformity) by Acharyas. The present study is done to trace the exact location of Urvi Marma according to modern anatomy, so that actual structure present at that site can be known which helps to elaborate Vidha lakashana (injury effect) of Urvi Marma.&nbsp

An Efficient Parallel Algorithm for Latin Square Design: A Multi Core CPU Approach

Abstract— The theory of Latin squares is very important tool in design theory. Like much of design theory, Latin squares have various applications in statistics, finite geometries and experimental design, to name a few. In this paper, we proposed an efficient parallel algorithm for Latin square design which have desirable properties for parallel array access. These squares provide conflict free access to various subsets of an n x n array using n memory modules. A transversal of such a square is a set of n entries such that no two entries share the same row, column or symbol. We present a general construction method for building parallel Latin square of order n2 for all n. The proposed algorithm presents a quick parallel method to produce a Latin square design and a parallel conflict access of data in SIMD system. The simulation results of the proposed parallel algorithm for Latin square design were compared with the traditional sequential algorithm Latin square design in terms of speedup and efficiency. The results of parallel Latin Square design were very promising and showed a potential that this design could successfully be applied to the parallel routing problems for conflict free data access. At last, the results show that the parallel versions of former sequential algorithm with simple modifications achieve the super linear speedup up to 200 times for matrix size of 256.   Index Terms: Latin square, multi core processor, parallel processing, simulation, parallel memory system, skewing scheme, multistage interconnection network

Hepatitis E rORF2p stimulated and unstimulated peripheral expression profiling in patients with self-limiting hepatitis E infection

To improve the current knowledge on the involvement of peripheral lymphocytes in hepatitis E virus (HEV) associated pathogenesis, we analyzed alterations in (1) immunophenotypic expressions (by flow cytometry) and (2) gene expression patterns (by TaqMan Low Density Array) of activatory, inhibitory, integrin, homing, ectonucleotidase machinery, costimulatory, inflammatory markers, and T regulatory cells (Treg) associated cytokines on HEV rORF2p stimulated and unstimulated PBMCs of 43 acute HEV patients, 30 recovered individuals, and 43 controls. The phenotypic expressions of key molecules CTLA-4, GITR, CD103, CD25, CD69, IL10 and TGF-1 in the acute patients and TGF-1 in the recovered individuals were significantly elevated on both unstimulated and stimulated PBMCs. Gene expression array data revealed upregulations of CD25, PD1, CD103, CCR4, IL10, and TGF-1 on both unstimulated and HEV rORF2p stimulated PBMCs of acute patients. The observed upregulations of inhibitory, integrin, activatory, and Treg-associated cytokine genes on the PBMCs of acute HEV patients complemented by their frequency data suggest them as the major players in the fine-tuning of immune response in self-limiting hepatitis E infection

STUDY OF IMPORTANCE OF KAKSHADHARA MARMA W. S. R TO ERBS PALSY

Ayurveda is one of the most reliable and complete medical science. The union of Mamsa, Sira, Snayu Asthi and Sandhi are called as Marma. Acharya Sushruta stated every aspect of Marma like definition, signs and symptoms of Marma injury. Total number of Marma as described in Samhitas are 107 in number. Marma science is one of the special aspects deeply elaborated by Ayurveda. Marma are several vital points on the body having importance regarding traumatic effect. These vital points when exposed to trauma generate the symptoms from pain to fatal effect. These points should be protected from injury. Detail knowledge of Marma is important from surgical point of view. Acharya Sushruta explain the Marma viddha lakshana in detail. Human body when expose to trauma shows various signs and symptoms depending on severity and type of trauma. when the trauma to the Kakshadhara Marma causes “Erbs Palsyâ€. Erbs palsy is the paralysis of the arm caused by injury to the upper trunk (c5-c6) of the brachial plexus. There are other ancient Indian sciences also in which the vital points of human body are described. The main aim of this study is to understand the kakshadhra Marma, its location in human body, its applied aspect and to find out any similarity with the vital points explain in Ayurved classics.

Security of Big Data over IoT Environment by Integration of Deep Learning and Optimization

This is especially true given the spread of IoT, which makes it possible for two-way communication between various electronic devices and is therefore essential to contemporary living. However, it has been shown that IoT may be readily exploited. There is a need to develop new technology or combine existing ones to address these security issues. DL, a kind of ML, has been used in earlier studies to discover security breaches with good results. IoT device data is abundant, diverse, and trustworthy. Thus, improved performance and data management are attainable with help of big data technology. The current state of IoT security, big data, and deep learning led to an all-encompassing study of the topic. This study examines the interrelationships of big data, IoT security, and DL technologies, and draws parallels between these three areas. Technical works in all three fields have been compared, allowing for the development of a thematic taxonomy. Finally, we have laid the groundwork for further investigation into IoT security concerns by identifying and assessing the obstacles inherent in using DL for security utilizing big data. The security of large data has been taken into consideration in this article by categorizing various dangers using a deep learning method. The purpose of optimization is to raise both accuracy and performance

Community, facility and individual level impact of integrating mental health screening and treatment into the primary healthcare system in Sehore district, Madhya Pradesh, India.

INTRODUCTION: Programme for Improving Mental Health Care (PRIME) designed a comprehensive mental healthcare plan (MHCP) for Sehore district, Madhya Pradesh, India. The objective of this paper is to describe the findings of the district-level impact evaluation of the MHCP. METHODS: Repeat community-based CS were conducted to measure change in population-level contact coverage for depression and alcohol use disorders (AUD), repeat FDS were conducted to assess change in detection and initiation of treatment for depression and AUD, and the effect of treatment on patient outcomes was assessed using disorder-specific prospective cohort studies. RESULTS: PRIME MHCP did not have any impact on contact coverage/treatment seeking for depression (14.8% at the baseline and 10.5% at the follow-up) and AUD (7.7% at the baseline and 7.3% at the follow-up) and had a small impact on detection and initiation of treatment for depression and AUD (9.7% for depression and 17.8% for AUD compared with 0% for both at the baseline) in the health facilities. Patients with depression who received care as part of the MHCP had higher rates of response (52.2% in the treatment group vs 26.9% in the comparison/usual care group), early remission (70.2% in the treatment group vs 44.8% in the comparison/usual care group) and recovery (56.1% in the treatment group vs 28.5% in the comparison/usual care group), but there was no impact of treatment on their functioning. CONCLUSIONS: While dedicated human resources (eg, Case Managers) and dedicated space for mental health clinics (eg, Mann-Kaksha) strengthen the 'formal' healthcare platform, without substantial additional investments in staff, such as Community Health Workers/Accredited Social Health Activists to improve community level processes and provision of community-based continuing care to patients, we are unlikely to see major changes in coverage or clinical outcomes

Charge transport mechanisms in monovalent doped mixed valent manganites

Abstract In this communication, we report the results of the studies on structural and transport properties of monovalent Na + doped La 1-x Na x MnO 3 (LNMO; x = 0.00, 0.05, 0.10, 0.15, 0.20, 0.25 and 0.30) manganites synthesized by conventional ceramic method. X-ray diffraction (XRD) and Rietveld refinements reveal the single phasic nature of LNMO manganites without any detectable impurity within the measurement range. Temperature dependent resistivity, under different applied magnetic fields, has been performed on LNMO samples. Samples understudy exhibit metal to insulator (semiconductor) transition at temperature T P which is strongly influenced by the substitution of Na + at La 3+ site. -T plots also exhibit resistivity upturn behavior at low temperature well below 40K under all the applied fields. Variation in T P and resistivity has been discussed in the context of the competition between the transport favoring tolerance factor and zener double exchange (ZDE) mechanism and transport degrading Jahn-Teller (JT) and size variance effects. In order to understand the mechanisms responsible for the charge transport in metallic and semiconducting regions and to explore the possible electronic processes responsible for the observed low temperature resistivity minima in all the presently studied LNMO manganites, various models have been employed. It has been found that VRH mechanism gets successfully fitted to the resistivity data in the semiconducting region while ZDE polynomial law is responsible for the charge conduction in metallic region for all the presently studied LNMO samples. A strong dependence of activation energy on the Na + -content as well as applied magnetic field has been discussed in the context of variation and interrelations between the structural parameters. Charge conduction in metallic region has been discussed in the light of electron-phonon interactions which is influenced by the Na + -content and applied magnetic field. Electrostatic blockade model has been employed to understand the low temperature resistivity minima behavior. Blocking energy for the charge carriers shows a dependence on the magnetic energy provided to the charge carriers. Present study can be useful to understand and to control the charge conduction in the manganites and hence to design the manganite based thin film devices for various spintronic applications