A Selective Bibliography, 1949 - 1965

Kennedy Space Center development from 1949 through 1965 - selected bibliography of article

The Λ\LambdaCDM growth rate of structure revisited

We re-examine the growth index of the concordance $\Lambda$ cosmology in the light of the latest 6dF and {\em WiggleZ} data. In particular, we investigate five different models for the growth index $\gamma$, by comparing their cosmological evolution using observational data of the growth rate of structure formation at different redshifts. Performing a joint likelihood analysis of the recent supernovae type Ia data, the Cosmic Microwave Background shift parameter, Baryonic Acoustic Oscillations and the growth rate data, we determine the free parameters of the $\gamma(z)$ parametrizations and we statistically quantify their ability to represent the observations. We find that the addition of the 6dF and {\em WiggleZ} growth data in the likelihood analysis improves significantly the statistical results. As an example, considering a constant growth index we find $\Omega_{m0}=0.273\pm 0.011$ and $\gamma=0.586^{+0.079}_{-0.074}$.Comment: 8 pages, 5 figures, Accepted for publication by International J. of Modern Physics D (IJMPD). arXiv admin note: substantial text overlap with arXiv:1203.672

Cosmology with X-ray Cluster Baryons

X-ray cluster measurements interpreted with a universal baryon/gas mass fraction can theoretically serve as a cosmological distance probe. We examine issues of cosmological sensitivity for current (e.g. Chandra X-ray Observatory, XMM-Newton) and next generation (e.g. Con-X, XEUS) observations, along with systematic uncertainties and biases. To give competitive next generation constraints on dark energy, we find that systematics will need to be controlled to better than 1% and any evolution in f_gas (and other cluster gas properties) must be calibrated so the residual uncertainty is weaker than (1+z)^{0.03}.Comment: 6 pages, 5 figures; v2: 13 pages, substantial elaboration and reordering, matches JCAP versio

Observational constraints on low redshift evolution of dark energy: How consistent are different observations?

The dark energy component of the universe is often interpreted either in terms of a cosmological constant or as a scalar field. A generic feature of the scalar field models is that the equation of state parameter w= P/rho for the dark energy need not satisfy w=-1 and, in general, it can be a function of time. Using the Markov chain Monte Carlo method we perform a critical analysis of the cosmological parameter space, allowing for a varying w. We use constraints on w(z) from the observations of high redshift supernovae (SN), the WMAP observations of CMB anisotropies and abundance of rich clusters of galaxies. For models with a constant w, the LCDM model is allowed with a probability of about 6% by the SN observations while it is allowed with a probability of 98.9% by WMAP observations. The LCDM model is allowed even within the context of models with variable w: WMAP observations allow it with a probability of 99.1% whereas SN data allows it with 23% probability. The SN data, on its own, favors phantom like equation of state (w<-1) and high values for Omega_NR. It does not distinguish between constant w (with w<-1) models and those with varying w(z) in a statistically significant manner. The SN data allows a very wide range for variation of dark energy density, e.g., a variation by factor ten in the dark energy density between z=0 and z=1 is allowed at 95% confidence level. WMAP observations provide a better constraint and the corresponding allowed variation is less than a factor of three. Allowing for variation in w has an impact on the values for other cosmological parameters in that the allowed range often becomes larger. (Abridged)Comment: 21 pages, PRD format (Revtex 4), postscript figures. minor corrections to improve clarity; references, acknowledgement adde

Using Energy Conditions to Distinguish Brane Models and Study Brane Matter

Current universe (assumed here to be normal matter on the brane) is pressureless from observations. In this case the energy condition is $\rho_0\geq0$ and $p_0=0$. By using this condition, brane models can be distinguished. Then, assuming arbitrary component of matter in DGP model, we use four known energy conditions to study the matter on the brane. If there is nonnormal matter or energy (for example dark energy with $w<-1/3$) on the brane, the universe is accelerated.Comment: 5pages, no figures; Accepted by Communications in Theoretical Physic

osteonecrosis of jaw onj impact of italian patients and role of italian physicians dentists and researchers in the growing evidence of a new disease

Purpose: Osteonecrosis of jaw (ONJ) is an uncommon but severe complication observed mostly in patients treated with bisphosphonates (BPs) for bone metastases, myeloma, osteoporosis (so called BRONJ, Bisphosphonate-Related Osteonecrosis of Jaw), but also with other drugs (bevacizumab, sunitinib, denosumab). The number of cases observed in Italy appears high in comparison with other countries and we present a review of several aspects of ONJ in Italy and the role of Italian health professionals and researchers on increasing knowledge and adequate reporting of ONJ phenomenon; Methods: Literature review about osteonecrosis of jaw (ONJ) with selection of Italian authors and publications, on year 2003-2011, by research on international electronic journal databases, Italian language journals, congress acta, web sources; Results: at October 2011, among 1272 papers published worldwide on ONJ issue, 128 (10%) were from Italian Authors; Conclusions: relevant articles by Italian groups were published about pathogenesis hypotheses, animal models, biology studies, risk factors, preventive measures, dental extraction protocols in BP-exposed patients, laser therapy, ozone therapy, surgical treatment. Experience of Italian patients suffering from ONJ, together with work of Italian dentists, physicians and researchers, appears of paramount importance in order to study ONJ and minimize a possible severe side-effect of efficacious medical treatments

A four-dimensional {\Lambda}CDM-type cosmological model induced from higher dimensions using a kinematical constraint

A class of cosmological solutions of higher dimensional Einstein field equations with the energy-momentum tensor of a homogeneous, isotropic fluid as the source are considered with an anisotropic metric that includes the direct sum of a 3-dimensional (physical, flat) external space metric and an n-dimensional (compact, flat) internal space metric. A simple kinematical constraint is postulated that correlates the expansion rates of the external and internal spaces in terms of a real parameter {\lambda}. A specific solution for which both the external and internal spaces expand at different rates is given analytically for n=3. Assuming that the internal dimensions were at Planck length scales when the external space starts with a Big Bang (t=0), they expand only 1.49 times and stay at Planck length scales even in the present age of the universe (13.7 Gyr). The effective four dimensional universe would exhibit a behavior consistent with our current understanding of the observed universe. It would start in a stiff fluid dominated phase and evolve through radiation dominated and pressureless matter dominated phases, eventually going into a de Sitter phase at late times.Comment: 12 pages, 8 figures; matches the version published in General Relativity and Gravitatio

Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

Alzheimer's disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-established strategy to avoid cAMP degradation is the inhibition of phosphodiesterase (PDE). In recent years, GEBR-32a has been shown to possess selective inhibitory properties against PDE type 4 family members, resulting in an improvement in spatial memory processes without the typical side effects that are usually correlated with this mechanism of action. In this work, we performed the HPLC chiral resolution and absolute configuration assignment of GEBR-32a. We developed an efficient analytical and semipreparative chromatographic method exploiting an amylose-based stationary phase, we studied the chiroptical properties of both enantiomers and we assigned their absolute configuration by 1H-NMR (nuclear magnetic resonance). Lastly, we measured the IC50 values of both enantiomers against both the PDE4D catalytic domain and the long PDE4D3 isoform. Results strongly support the notion that GEBR-32a inhibits the PDE4D enzyme by interacting with both the catalytic pocket and the regulatory domains

Multiple Λ\LambdaCDM cosmology with string landscape features and future singularities

Multiple $\Lambda$CDM cosmology is studied in a way that is formally a classical analog of the Casimir effect. Such cosmology corresponds to a time-dependent dark fluid model or, alternatively, to its scalar field presentation, and it motivated by the string landscape picture. The future evolution of the several dark energy models constructed within the scheme is carefully investigated. It turns out to be almost always possible to choose the parameters in the models so that they match the most recent and accurate astronomical values. To this end, several universes are presented which mimick (multiple) $\Lambda$CDM cosmology but exhibit Little Rip, asymptotically de Sitter, or Type I, II, III, and IV finite-time singularity behavior in the far future, with disintegration of all bound objects in the cases of Big Rip, Little Rip and Pseudo-Rip cosmologies.Comment: LaTeX 11 pages, 10 figure