The neutron production rate measurement of an indigenously developed compact D-D neutron generator

One electrostatic accelerator based compact neutron generator was developed. The deuterium ions generated by the ion source were accelerated by one accelerating gap after the extraction from the ion source and bombarded to a target. Two different types of targets, the drive - in titanium target and the deuteriated titanium target were used. The neutron generator was operated at the ion source discharge potential at +Ve 1 kV that generates the deuterium ion current of 200 mA at the target while accelerated through a negative potential of 80 kV in the vacuum at 1.3×10-2 Pa filled with deuterium gas. A comparative study for the neutron yield with both the targets was carried out. The neutron flux measurement was done by the bubble detectors purchased from Bubble Technology Industries. The number of bubbles formed in the detector is the direct measurement of the total energy deposited in the detector. By counting the number of bubbles the total dose was estimated. With the help of the ICRP-74 neutron flux to dose equivalent rate conversion factors and the solid angle covered by the detector, the total neutron flux was calculated. In this presentation the operation of the generator, neutron detection by bubble detector and estimation of neutron flux has been discussed

The Clinical Aspects of Saroglitazar and its Side Effects

The new substance element has been known as novel antidiabetic drug, eg: saroglitazar. saroglitazar is a medication used to treat type-2 diabetes. saroglitazar was known under the exchange name Lipaglyn, created by Zydus cadila. lipaglyn is the first drug approved to treat type-2diabetes mellitus by the drug controller general of India in june 2013. Lipaglyn is demonstrated for the patients experiencing diabetes dyslipidaemia. It is given once daily for treatment. Saroglitazar manages the lipid parameters just as glycemic control. [1] Keywords: Anti-diabetic, dual PPAR agonist, glitazar, hypertriglyceridemia, insulin sensitizer, Lipaglyn, AE’s (adverse effects)

Simulation studies of the ion beam transport system in a compact electrostatic accelerator-based D-D neutron generator

The study of an ion beam transport mechanism contributes to the production of a good quality ion beam with a higher current and better beam emittance. The simulation of an ion beam provides the basis for optimizing the extraction system and the acceleration gap for the ion source. In order to extract an ion beam from an ion source, a carefully designed electrode system for the required beam energy must be used. In our case, a self-extracted penning ion source is used for ion generation, extraction and acceleration with a single accelerating gap for the production of neutrons. The characteristics of the ion beam extracted from this ion source were investigated using computer code SIMION 8.0. The ion trajectories from different locations of the plasma region were investigated. The simulation process provided a good platform for a study on optimizing the extraction and focusing system of the ion beam transported to the required target position without any losses and provided an estimation of beam emittance

Angiolymphoid hyperplasia with eosinophilia during pregnancy: A study of three cases with a brief review of literature

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon and benign vascular disorder characterized by angiomatous, pink-red papulonodular lesions located on the scalp, neck, and peri and post-auricular areas. The exact cause of ALHE being unknown, several etiological factors such as trauma, insect bites, hyperestrogen states, and immunological factors have been implicated in the pathogenesis of the disease. A few cases of pregnancy-related ALHE have been reported in the literature. In this study, we report three cases of ALHE, which were aggravated during the first trimester of pregnancy, along with their management. The relation between ALHE and pregnancy is discussed with a brief review of the literature

Large congenital melanocytic nevus with metastatic melanoma with a probable primary in the lung

Large congenital melanocytic nevi (>20 cm in greatest diameter) are very rare and are seen in approximately 1 in 20,000 newborns. The major risk these patients face is the development of neurocutaneous melanosis or malignant melanoma. We report a rare case of large congenital melanocytic nevus with metastatic melanoma in a 40-year-old woman. In this case, though the primary was not established with certainty, on the basis of clinical course and radiological evaluation of various organs, we presume that the primary could be in the lung

Sinus of Valsalva Aneurysm: A case report

Sinus of Valsalva aneurysm (SVA) is an uncommon cardiac anomaly that can be congenital or acquired. Sinus of Valsalva aneurysm (SVA) is one of the rare congenital anomalies described in the literature, prevalence being 1% of all congenital anomalies of heart and circulation. Risks associated with SVA include rupture, compression of adjacent cardiac structures and development of aortic regurgitation. Rupture is the most dreaded complication of SVA. Ruptures of sinus of valsalva aneurysm are most commonly seen rupturing into cardiac chambers. In our case, the rupture was into inter ventricular septum which is very rare. The rent in the sinus of valsalva should always be closed using patch material and we should never close directly. We should always excise one side of the cavity preferably towards left ventricle. Rupture of sinus of valsalva to inter ventricular septum is very rare. Accurate pre operative diagnosis and proper treatment will help in long term survival

Left Ventricular Pseudo aneurysm: A case report

Rupture of the free wall of the left ventricle (LV) is a catastrophic complication occurring in 4% of patients after myocardial infarction (MI) and in 23% of those who die of MI. It is caused by myocardial rupture contained within the pericardium and is characterized by the absence of true myocardial tissue in its wall unlike, a true aneurysm which involves the full myocardial wall thickness. Early diagnosis is mandatory using noninvasive modalities such as TTE and CMR or less commonly used nowadays invasive modalities such as coronary arteriography and left ventriculography. Due its high liability for fatal rupture urgent surgical intervention is of paramount importance in management of this pathology. We present a rare case of Left Ventricular Pseudo aneurysm in young patient who underwent previous surgery for peri-cardial effusion. The surgical goal is to preserve or to remodel the ventricular chamber anatomy. Left ventricular angiogram is the definitive test to clinch the correct diagnosis. A high index of clinical suspicion is needed to avoid missing the diagnosis. This particular patient might have developed left ventricular pseudo aneurysm as a result of trauma from previous surger

Chorea: Secondary to Non-Ketotic Hyperglycemia: A Case Report

Chorea associated with non-ketotic hyperglycaemia is an uncommon dyskinetic syndrome in uncontrolled or undiagnosed diabetes. Various theories are postulated but the underlying mechanism remains poorly understood. We report a 70-year-old man suffering from sudden choreodystonic movements and undiagnosed hyperglycemia. It always marks the importance of screening for diabetes as a cause of acute onset of hyperkinetic disorders.&nbsp;</p

Assessment of Variability of Rainfall and Canal Water under Telugu Ganga Project Command in Andhra Pradesh

The present study was conducted to make a detailed assessment of the variability and relationships of rainfall (mm) received, canal water (Mcum) supplied and the yield (kg/ha) of major crops viz., paddy, groundnut, sugarcane, sorghum and cotton crops attained under the Telugu Ganga Project (TGP) command area in Andhra Pradesh during 1997 to 2021. The crop productivity would always be influenced by the water resource available to a crop. Accordingly, linear and quadratic regression models of yield were calibrated to predict the yield of crops through canal water supplied in different years. The regression models were assessed based on the significance of coefficient of determination (R2) and magnitude of prediction error (PE) of the yield over years. The canal water released in different years was found to significantly influence the yield of paddy, groundnut, cotton and sugarcane crops under the TGP command area. The quadratic regression models gave higher and significant values of R2 compared to the linear regression models calibrated for different crops. The predictability of yield was found to be 0.725 under quadratic model compared to 0.605 under linear model for paddy, while it was 0.458 under quadratic model compared to 0.406 under linear model for groundnut. In case of sugarcane, the predictability of yield was found to be 0.488 under quadratic model compared to 0.431 under linear model. The models were found to be useful for prediction of yield of crops through varying levels of canal water released in different years. This will greatly help to efficiently utilize the canal water resources with regard to the quantity and frequency of water to be provided for irrigation of crops. Since the canal water released under TGP command area is highly assured,we recommend that the farmers could efficiently utilize the available canal water by growing less water requiring crops and attain maximum yield and profit by adopting the improved agricultural technologies of different crops grown under the TGP command area