Molecular structure of t-butyloxycarbonyl-Leu-Aib-Pro-Val-Aib-methyl ester, a fragment of alamethicin and suzukacillin: A 3<SUB>10</SUB>-helical pentapeptide

The pentapeptide Boc-Leu-Aib-Pro-Val-Aib-OMe, a fragment of alamethicin and suzukacillin, crystallizes in the space group P21, with a = 11.034 (2), b = 10.894 (2), c = 15.483 (2) &#197;, &#946;= 104.80 (2)&#176; and Z = 2. The crystal structure has been solved by direct methods and refined to an R value of 0.069. The peptide backbone folds into a right-handed 310-helical conformation, stabilized by two intramolecular 4&#8594; 1 hydrogen bonds between the Leu(1) CO and Val(4) NH and Aib(2) CO and Aib(5) NH groups. The solid-state conformation is consistent with results of spectroscopic analysis in solution

Image Segmentation Based on Doubly Truncated Generalized Laplace Mixture Model and K Means Clustering

The present paper aims at performance evaluation of Doubly Truncated Generalized Laplace Mixture Model and K-Means clustering (DTGLMM-K) for image analysis concerned to various practical applications like security, surveillance, medical diagnostics and other areas. Among the many algorithms designed and developed for image segmentation the dominance of Gaussian Mixture Model (GMM) has been predominant which has the major drawback of suiting to a particular kind of data. Therefore the present work aims at development of DTGLMM-K algorithm which can be suitable for wide variety of applications and data. Performance evaluation of the developed algorithm has been donethrough various measures like Probabilistic Rand index (PRI), Global Consistency Error (GCE) and Variation of Information (VOI). During the current work case studies forvarious different images having pixel intensities has been carried out and the obtained results indicate the superiority of the developed algorithm for improved image segmentation

Studies on the Performance of Air Cyclone Separator for Removal of Particulate Matter

Emissions from industries and air pollution from these emissions adversely affects the environment and public health. For instance, India depends largely on coal for its power generation. The problem with Indian coal is that it carries a lot of dust with it. Hence, dust carried along with the flue gases has to be separated before sending the gases for further treatment. Cyclone separa-tor, bag filter and electrostatic precipitator have found applications in technological use. ESP demands high voltage (power requirements) whereas general bag filters cannot work beyond 120C. However, cyclone separators have less temperature and pressure limitations and requires low pressure drop. Hence, cyclone separators are usually selected to separate dust from fluid streams

Impact of recent cyclone on the marine fishery sector along the east Godavari and Visakhapatnam districts of Andhra Pradesh

A cyclone which lashed along the coastal Andhra Pradesh on the night of 6-11-'96 resulted in the loss of thousands of human lives and materials. The coast of East Godavari and parts of Visakhapatnam districts were the worst hit areas with high velocity winds bringing in huge tidal waves which inundated the fish landing centres

CONSIDER UNDERSIZED TEXTS BY ASSEMBLE & EVALUATE SEMANTIC KNOWLEDGE

They have rehabilitated some relevant studies, such as online scraping, an email study by unwanted email about the operation of the Aristotelian application and the incorrect interpretation of the roaming programs that are still under study. To avoid overcoming the critical gap announced to develop an agreement, accept a false classification system designed for mobile devices. The subsequent fraud in the payment system is impossible and the undeveloped scams are a violently regenerated system designed for emergency distortion programs. More developed provinces have been developed to adopt extortion classifications. Boldly defines the technology of modified adaptive songs, taking into account the testimonies of people with complete patterns of patterns, evaluation and behavior analysis that show the standard ideas of compliance

A Novel Multi-Functional DSTATCOM with Distribution Generation using FRC Controller

Distribution Generation plays a significant role in remote areas where the utility grid is affected and initializing by renewable energy sources to acquire the sufficient power demand. In distribution system, it is very exigent consumer related concern which is confronted due to mis-operation of massive non-linear load apparatus. A multi-functional distributed static compensator incorporates the best choice for enhancing the power quality features with effective control scheme under rambled non-linear loads. Conventional control schemes are more adversed with greater switching losses due to extreme harmonic frequencies in a refernce current component. This paper proposes, a novel multi-objective fundamental reference current control scheme based multi-functional DSTATCOM furnishes the current harmonic compensation at PCC, reactive power compensation, power factor correction, active power exchanging, minimizing the switching losses, incredible efficiency and power factor correction. The validation of proposed multi-functional DSTATCOM with proposed control strategy under rated capacity of distribution generation is evaluated by using Matlab/Simulink platform and simulation results are presented

An Approach Ahead Product Counterfeiting Identification for BIRTHMARKS in Light of DYKIS

Programming skin pigmentation will be an exceptional trademark of a project. Thus, thinking about the birthmarks between those plaintiff What's more respondent projects gives a compelling methodology for programming counterfeiting identification. However, programming skin pigmentation era appearances two principle challenges: the non attendance of source book What's more different code confusion systems that endeavour should shroud the aspects of a system. We recommend another sort for product skin pigmentation known as progressive magic direction book grouping (DYKIS) that might a chance to be concentrated from an executable without the have for source book. Those counterfeiting identification calculation In view of our new birthmarks will be versatile to both powerless confusion strategies for example, compiler optimizations and solid confusion systems executed clinched alongside instruments for example, such that sand mark, allatori What's more upx. We recommended an instrument known as DYKIS-PD (DYKIS counterfeiting identification tool) Furthermore require on direct examinations ahead vast number about double projects

Development and validation of RP HPLC method for determination of metformin and sitagliptin in bulk and pharmaceutical dosage form

A simple and rapid reversed phase-high performance liquid chromatographic method was developed for simultaneous determination of Metformin and Sitagliptin in Tablet Dosage form. The elution was done with a mobile phase of Water: Methanol (60:40) on Intersil-BDS C18 column (250 × 4.6 mm, 5 μm particle size). The wavelength detector was set at 258 nm. Retention times for Metformin and Sitagliptin were around 2.869 min, 3.942 min respectively. The reliability and analytical performance of the proposed HPLC procedure were statistically validated according to the respect of linearity, ranges, precision, accuracy, repeatability, reproducibility, detection and quantification limits. Linear ranges were established between 20-80 μg/mL for both the drug. The LOD and LOQ for Metformin were found to be 0.663, 1.92 and for Sitagliptin were found to be 0.405, 1.228 respectively. The described High Performance Liquid Chromatography method was successfully employed for the analysis of pharmaceutical formulations containing combined dosage for

A New Technique to find the effect of Active Power Loading on Voltage Stability and Algorithm to improve Voltage Stability of Radial and Meshed Power Systems

This paper will analyze the impact of active power on voltage stability of radial and meshed systems and a new algorithm is proposed which would indicate the amount and location at which the active power is to be reduced to improve the voltage stability of entire power system or set of buses that are prone to voltage instability. A new sensitivity matrix named Active Power L-Index sensitivity matrix is been proposed. The proposed approach is simple and easy to be implemented into large power systems. The proposed approach has been applied to several Indian rural distribution networks and IEEE 14-bus test system which demonstrated applicability of the proposed approach. Index Terms- L-index matrix, Jacobian matrix, sensitivity, Active Power L-Index sensitivity matri