Ethnobotanical Studies on Some Rare and Endemic Floristic Elements of Eastern Ghats-Hill Ranges of South East Asia, India

The Eastern Ghats, one of the nine Floristic Zones in India. Eastern Ghats are spread over three States of India, namely Orissa, Andhra Pradesh and Tamil Nadu. The hilly areas of Eastern Ghats in Andhra Pradesh are mainly inhabited by 33 aboriginal/tribal communities, who still practice the age old traditional medicines and their application. There are 62 different tribes, inhabited in Orissa. The inhabitants of the aboriginal tribal communities, who still practice the age old traditional medicines and their applications. The author undertook ethno medicobotanical studies in Eastern Ghats along with systematic survey. Many tribal people depending on naturally growing or wild plants for their food and medicine in this region. The study during 1997-2005 brought to light, many unknown uses of plants which are interesting has been collected by the author. The present paper deals with some rare and endemic plant ethnobotanical uses of Eastern Ghats

Ethno-Medico-Botanical Studies From Rayalaseema Region of Southern Eastern Ghats, Andhra Pradesh, India

This paper deals with Ethno- Medico botanical Studies of Rayalaseema Region, Andhra Pradesh, India. An ethno-botanical survey was carried out in Seshachalam hills of Chittoor District, Palakondas and Lankamalais of Kadapa District, Errmalais and Nallamalai hills of Kurnool District and some other isolated hill ranges in Ananthapur District are Kalasamudram-Nigidi forest range, Amagondapalem hills and Kikati forest

Evaluation of genetic diversity among <i style="">Jatropha curcas</i> (L.) by RAPD analysis

283-288 The genetic diversity and pedigree analysis of Jatropha curcas (L.) was evaluated through RAPD markers. A total number of 10 accessions, collected from different ecoclimatic zones of India, were screened with 43 random decamer primers to evaluate polymorphism. Selected 10 primers generated 125 bands, 76 of which were found to be polymorphic. The amplification products ranged from 9-14 bands for different primers. Each primer produced on an average 12.5 bands per primer, of which 7.6 were polymorphic. UPGMA method was used to construct dendrogram and genetic distance matrix was determined using squared Euclidean distances. Cluster analysis of data using UPGMA algorithm placed the ten accessions into two main clusters, the genetic dissimilarity matrix between genotypes ranged from 0-8 and the principal component analysis placed the 10 accessions into three groups. </smarttagtype

3D Structure Development of Chikungunya Virus and its Structural Characterization &#x2013; an In silico approach

The 3 Dimensional structure of a protein is an expedient for structure based drug design and identifying the conformational epitopes that are foremost for designing the vaccines. Chikungunya (CHIKV) is a heat sensitive RNA virus which causes a viral disease which is transmitted in humans by human-mosquito-human transmission. Disease mostly found in the tropic and subtropical countries mainly in South India and in few other Asian countries. The primary transmission agents of Chikungunya Virus are yellow fever mosquito (_Aedes aegypti_) and forest day mosquito (_Aedes albopictus_). The forest day mosquito bites during day time and hence day time mosquito bite is the main reason for transmission. The main distinctive of the disease is a fever along with an arthritic type of pain in the joints. 3D Structure of Chikungunya virus is not encountered in the PDB Databank. A Comparative modeling method was used for the prediction of the 3D structure of Chikungunya virus. Modeled structure prvided substantial parameters under Ramachandran plot and stereochemical aspects of main chain and side chains through PROCHECK analysis. Finally the energy minimization protocols yielded a score of -12063.947 KJ/Mol and RMSD Value of 0.29oA. Structure Validation procedures proffer the use of present modeled structures for structure based drug design and other confirmative applications