Chronicles of Oklahoma

Article explains how pioneer newspapers published within Oklahoma Territory provided glimpses into the customs and culture of early pioneers

Nurses\u27 Alumnae Association Bulletin - Volume 16 Number 1

Alumnae Notes ANA Biennial Convention Cancer of the Cervix, Uterus and Ovaries Committee Reports Digest of Alumnae Association Meetings Greetings from Miss Childs Greetings from the President Graduation Awards - 1950 Isotopes and the Nurse - Dr. T.P. Eberhard Marriages Necrology New Arrivals Nursing Care in Heart Disease with Pulmonary Infarction Nursing Care of a Mitral Commissurotomy Physical Advances at Jefferson - 1950 Policies of the Private Duty Nurses\u27 Registry Staff Activities, 1950-1951 Students\u27 Corner The Department of Surgical Research - Drs. Templeton and Gibbon White Haven and Barton Memorial Division

Prevention of supersensitivity in partially isolated cerebral cortex

1. 1. A portion of the marginal gyrus of the cerebral cortex on each of fifteen cats was undercut 3-4 mm deep. In terminal experiments under chloralose, 2-18 weeks later, local electrical stimulation produced after-discharges (in 12 cats) which had a longer duration on the undercut side than on the intact side.2. 2. Another group of seventeen cats, each with an undercut marginal gyrus, received daily electrical stimulation (subthreshold for after-discharges) of the undercut cortex starting 1 week after undercutting (6 weeks delay in two cats). Total stimulation was about 400 applications at 0.6 mA, 400 at 0.8 mA and 200 at 1.0. mA. In terminal experiments under chloralose 1 week after the end of stimulation (6 weeks for one cat), fourteen of these cats did not show supersensitivity of the undercut cortex.3. 3. These results suggest that chronic electrical stimulation can prevent the development of supersensitivity.Abstract1. 1. Sur quinze chats, une partie du gyrus marginal du cortex cerebral est isolee par section sous-corticale a 3-4 mm de profondeur. Dans des experiences terminales sous chloralose, pratiquees 2-18 semaines plus tard, la stimulation electrique locale determine des post-decharges (chez 12 chats) d'une duree plus longue du cote sectionne que du cote sain.2. 2. Un autre groupe de dix-sept chats, chacun avec un gyrus marginal isole par section sous-corticale, recoit des stimulations quotidiennes (sous-liminaire pour les post-decharges) sur le cortex sectionne a partir d'une semaine apres la section (ce delai a ete de 6 semaine pour deux chats). La stimulation totale est d'environ 400 applications de 0,6 mA, 400 de O,8 mA et 200 de 1,0 mA. Des experiences terminales sous chloralose une semaine apres la fin de la stimulation (6 semaines pour un chat), montrent que quatorze chats ne presentent plus d'hypersensibilite du cortex sectionne.3. 3. Ces resultats suggerent que la stimulation electrique chronique peut prevenir le developpement de l'hypersensibilite.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/33291/1/0000684.pd

Nurses\u27 Alumnae Association Bulletin - Volume 6 Number 9

Remember the Relief Fund Welcome! Miss Childs Financial Report Calendar of Coming Events Lest You Forget! Attention Review of the Alumnae Association Meetings Institutional Staff Nurses\u27 Section Report of Staff Activities - 1947-1948 Private Duty Section The White Haven Division Barton Memorial Division Remember the Relief Fund Student Nurses\u27 Activities Jefferson Scores Again The Clara Melville Scholarship Fund Interesting Activities of the Nurses\u27 Home Committee of the Women\u27s Board Exclusive for Nurses Changes in the Maternity Division Gray Lady Musical Therapy Service Memorial Service Honoring Mrs. Bessie Dobson Altemus The Blood Donor Center The Hospital Pharmacy Medical College News Remember the Relief Fund Administrative Staff and Faculty of the School of Nursing Streptomycin Changes in the Staff at Jefferson Hospital Care of the Thoracic Surgical Patient Miscellaneous Items Marriages New Arrivals Deaths The Bulletin Committee Attention, Alumnae New Addresse

Sequence analysis and characterization of active human alu subfamilies based on the 1000 genomes pilot project

© The Author(s) 2015. The goal of the 1000 Genomes Consortium is to characterize human genome structural variation (SV), including forms of copy number variations such as deletions, duplications, and insertions. Mobile element insertions, particularly Alu elements, are major contributors to genomic SV among humans. During the pilot phase of the project we experimentally validated 645 (611 intergenic and 34 exon targeted) polymorphic young Alu insertion events, absent fromthe human reference genome. Here, we report high resolution sequencing of 343 (322 unique) recent Alu insertion events, along with their respective target site duplications, precise genomic breakpoint coordinates, subfamily assignment, percent divergence, and estimated A-rich tail lengths.All the sequenced Alu lociwerederived from the Alu Y lineagewith no evidence of retrotransposition activity involving older Alu families (e.g., AluJandAluS). AluYa5 is currently themost active Alu subfamily in the human lineage, followed by AluYb8, andmany others including three newly identified subfamilieswe have termed AluYb7a3, AluYb8b1, and AluYa4a1. This report provides the structural details of 322 unique Alu variants from individual human genomes collectively adding about 100 kb of genomic variation. Many Alu subfamilies are currently active in human populations, including a surprising level of AluY retrotransposition. Human Alu subfamilies exhibit continuous evolution with potential drivers sprouting new Alu lineages

Nurses Alumni Association Bulletin, Fall 1991

Annual Meeting Calendar Annual Luncheon - Meeting Notice Meeting Notice Dates Officers and Committee Chairmen President\u27s Message Treasurer\u27s Report Proposed Budget- 1991 News About Our Graduates History of the School of Nursing The Future of Nursing School Health - 20 Years Ago - Today Happy Birthday Resume of Minutes of Alumni Association Meetings Alumni Office News Committee Reports By-Laws Bulletin Nominating Relief Fund Satellite Scholarship Social Finance Nursing Education at Jefferson - A Century of Excellence The Decade Fund Fiftieth Anniversary In Memoriam, Names of Deceased Graduates Luncheon Photos My Dear Son Weather Lore Class News Scholarship Application Non-Graduate Scholarship Fund Application Relief Fund Application Centennial Tile Order Form Membership Application Pins, Transcripts, Class Address Lists, Change of Address Form Ma

Solving Navigational Uncertainty Using Grid Cells on Robots

To successfully navigate their habitats, many mammals use a combination of two mechanisms, path integration and calibration using landmarks, which together enable them to estimate their location and orientation, or pose. In large natural environments, both these mechanisms are characterized by uncertainty: the path integration process is subject to the accumulation of error, while landmark calibration is limited by perceptual ambiguity. It remains unclear how animals form coherent spatial representations in the presence of such uncertainty. Navigation research using robots has determined that uncertainty can be effectively addressed by maintaining multiple probabilistic estimates of a robot's pose. Here we show how conjunctive grid cells in dorsocaudal medial entorhinal cortex (dMEC) may maintain multiple estimates of pose using a brain-based robot navigation system known as RatSLAM. Based both on rodent spatially-responsive cells and functional engineering principles, the cells at the core of the RatSLAM computational model have similar characteristics to rodent grid cells, which we demonstrate by replicating the seminal Moser experiments. We apply the RatSLAM model to a new experimental paradigm designed to examine the responses of a robot or animal in the presence of perceptual ambiguity. Our computational approach enables us to observe short-term population coding of multiple location hypotheses, a phenomenon which would not be easily observable in rodent recordings. We present behavioral and neural evidence demonstrating that the conjunctive grid cells maintain and propagate multiple estimates of pose, enabling the correct pose estimate to be resolved over time even without uniquely identifying cues. While recent research has focused on the grid-like firing characteristics, accuracy and representational capacity of grid cells, our results identify a possible critical and unique role for conjunctive grid cells in filtering sensory uncertainty. We anticipate our study to be a starting point for animal experiments that test navigation in perceptually ambiguous environments