Features of childhood acute myeloid leukemia in Iran: A report from double center study

Acute Myeloblastic Leukemia is one of the important malignancies in children. For better managing the prognosis of this disease, there should be enough information about common features of this malignancy. The aim of this study was to evaluate these common features in children with Acute Myeloblastic Leukemia. A total of 104 eligible children less than 15-year-old have been referred from 2007-2011 to two referral centers for childhood malignancies. Basic epidemiological information recorded in checklists for each individual. Analyzes have been done by SPSS version 22. Out of patients, 57 cases were males (54.8). The male/female ratio was 1.2. The mean age of patients was 6.5 ± 4.3 years. The majority subtypes of patients were M3, M4, non-M3, and M2, respectively. The common molecular abnormalities were t (15;17) and inv (16). Of patients, 19.2 had an early relapse. The mean age of relapse in patients was 6.7 ± 3.9 years. Sixty patients (57.7) were alive, and 44 cases (42.3) died during or after therapy. The three years overall survival rate of patients was 42 in this study. According to our data, AML has the same frequency as compared with data from developing countries. But different epidemiological characteristic was a lower rate of three years overall survival in patients. These data may serve the health authorities for more effective environmental and preventive measurements, purposeful allocation of resources for facilitating upto-date diagnostic and treatment modalities, psychological support programs for respective family members and educational purposes. © 2015 Tehran University of Medical Sciences. All rights reserved

A Case Report of Newborn with Thrombocytosis Born to an Opioid-addict Mother

Abstract: Neonatal thrombocytosis is a very rare phenomenon in infants born to addict mothers. It can be due to opioids withdrawal and occurs a few days after delivery. The etiology is unknown and it is eradicated gradually without any complication. The reported neonate was born to a heroin addict mother who has used methadone during pregnancy. The neonate was admitted in 14th day of life in neonatal intensive care unit (NICU) with the diagnosis of withdrawal syndrome and supportive care was administered for him. Thrombocytosis was detected in routine lab tests. There was not any reason for it except his mother’s addiction. The platelet count was 1,168,000 in the first day and decreased gradually during 28 days to 739,000. There was not any complication and no special treatment was administered. This case indicates that thrombocytosis may happen as a part of neonatal abstinence syndrome and is eradicated without any complication. Keywords: Thrombocytosis, Neonatal abstinence syndrome, Opioids, Methadon

Evaluation of Volunteer Barley Interference on Growth Indices of Some Wheat CultivarsCultivars

Abstract \ud To evaluate interference effects of volunteer barley on growth indices of six wheat cultivars, a study conducted in Sabzevar region during 2007-2008 growing season. The experiment was established as randomized complete block design with factorial arrangement and three replications. The treatments were six wheat cultivars in weedy and weed free situation. The studied cultivars including: 1- Chamran 2- Gascogen 3- Mahdavi 4- Pishtaz 5- Shiraz and 6- Falat with densities of 350, 375, 375, 400, 400, 325 seed m-2. Valfajr cultivar was used as a volunteer barley with density of 50 plant m-2. Base on variance analyze results volunteer barley interference reduced grain yield, leaf aria index, relative growth rate, crop growth rate, height and dry matter accumulation of wheat cultivars. The maximum of grain yield in monoculture and mixedculture was obtained in Shiraz and Mahdavi cultivars, respectively and the minimum values was found in Gascogen and Chamran cultivars, respectively. The maximum of leaf area index in monoculture and mixedculture were in Mahdavi cultivar, which could be caused by higher height and thus increased shading on volunteer barley and limitation on its growth. Comparison of cultivars relative growth rate in monoculture and mixedculture showed that Mahdavi cultivar had minimum reduction of relative growth rate. Moreover crop growth rate of Shiraz cultivar in monoculture and Mahdavi cultivar in mixedculture was greater than other cultivars. Results showed that yield of evaluated cultivars in volunteer barley interference situation were affected by height, leaf area index, relative growth rate, crop growth rate and accumulated dry matter, and Mahdavi cultivar showed better performance in these traits.\ud \ud Keywords: Grain yield, Competition, Leaf area index, Relative growth rate, Crop growth rate, Dry matter accumulatio

A case report of newborn with thrombocytosis born to an opioid-addict mother

Neonatal thrombocytosis is a very rare phenomenon in infants born to addict mothers. It can be due to opioids withdrawal and occurs a few days after delivery. The etiology is unknown and it is eradicated gradually without any complication. The reported neonate was born to a heroin addict mother who has used methadone during pregnancy. The neonate was admitted in 14th day of life in neonatal intensive care unit (NICU) with the diagnosis of withdrawal syndrome and supportive care was administered for him. Thrombocytosis was detected in routine lab tests. There was not any reason for it except his mother's addiction. The platelet count was 1,168,000 in the first day and decreased gradually during 28 days to 739,000. There was not any complication and no special treatment was administered. This case indicates that thrombocytosis may happen as a part of neonatal abstinence syndrome and is eradicated without any complication

Assessing concrete strength by means of small diameter cores

Estimation of concrete strength may be gained from compression tests conducted on cores having a diameter considerably smaller than the recommended one of 100 mm. This paper examines the results of tests applied on the 69 and 46 mm diameter cores. A total number of 2982 cores was tested. The effects of both specimen and aggregate sizes for different length-to-diameter (l/d) ratios on the compressive strength of smaller diameter cores were analysed. The core strengths were compared to those of standard cylinder and cubes. Test results showed that maximum size and type of aggregate significantly affect the strengths of small diameter cores. As the maximum aggregate size increased the strength of core decreased. The strengths of cores removed from crushed aggregate-bearing concrete were somewhat higher than those of ones drilled from natural aggregate-containing concrete. Test results also revealed that the l/d ratio of the specimen is more effective for small diameter cores. The age of concrete was found to be an important factor in the interpretation of the results, the older the concrete the higher the core strength. The coefficient of variation of strength values were noticed to be somewhat higher for 46 mm diameter cores and cores drilled from natural aggregate-containing concrete mixtures. It was indicated that core strength was affected by both specimen and aggregate sizes. Therefore, it was proposed that the size of specimen and aggregate, type of aggregate, age of the specimen should be taken into consideration for the interpretation of the results used to convert the strengths of cores to those of standard cylinders or cubes. © 2006 Elsevier Ltd. All rights reserved.Firat University Scientific Research Projects Management Unit: 04 02 01, 03 02 23The authors would like to acknowledge the financial and technical supports supplied by Scientific Research Projects Commission of Anadolu University, Turkey (Projects 03 02 23 and 04 02 01). -

Performance of carbon, polyvinylalcohol and steel based microfibers on alkali-silica reaction expansion

The performance of carbon, polyvinylalcohol (PVA) and steel microfibers on alkali silica reaction (ASR) were investigated. Two series of mortar specimens containing different amounts of microfibers were cast. One of the series was cured in accordance with ASTM C1260 test method, while other series were additionally cured at 23 degrees C in water for 14 days before standard ASTM C1260 curing period. Extended curing was found to be effective on reduction of ASR expansions in all of the mixtures containing any type of microfibers used in this study. This may be due to enhancement of matrix-microfiber bonding. ASR expansions were reduced by increasing the microfiber content in the specimens subjected to extended curing. (C) 2007 Elsevier Ltd. All rights reserved