O Carrinho da Ciência: oportunidades de ensino e de interações entre os saberes

This work concerns the studies carried out by a group of undergraduate Chemistry students, involving practical classes performed using a mobile laboratory, mounted on a supermarket cart. This was undertaken at the Aurelino Leal state school in Itacare (Bahia), as an extension activity of the Tutorial Education Program for the Degree in Chemistry, at the Federal University of Sao Carlos (Araras campus). Practical activities were held in classrooms, using a methodology based on interactive scientific questions, where the students achieved results from the discussions and debates proposed. The undergraduates, as teachers, were mediators in the teaching-learning process, obtaining significant results, considering the involvement of the high school students in the process. The experience showed that the mobile laboratory was an important resource that facilitated the movement of materials, such as glassware and reagents, to the classrooms, in addition to stimulating class participation in the discussion of experiments. The university students had the opportunity to create a method for experimental classes, develop a plan, and put the proposals into practice, while interacting with the local cultural diversity, strengthening the inseparability among teaching, research, and university extension.Este trabajo se refiere a los estudios que realiza un grupo de estudiantes de profesorado en química al implementar clases prácticas a través de un laboratorio itinerante, estructurado en un carrito de supermercado. La experiencia se desarrolló en la Escuela Estatal Aurelino Leal en Itacaré-BA, a través de una actividad de extensión del Programa de Educación Tutorial – Profesorado en Química de la Universidad Federal de São Carlos (UFSCar), campus Araras-SP. Las actividades prácticas se llevaron a cabo en las aulas, utilizando una metodología basada en preguntas científicas interactivas, en las que los estudiantes lograban los resultados a partir de las reflexiones y debates propuestos. Los estudiantes de profesorado asumieron la función de profesores y fueron mediadores en el proceso de enseñanza-aprendizaje, obteniendo resultados significativos, dada la implicación de los estudiantes de la escuela en el proceso. La experiencia ha demostrado que el laboratorio móvil fue un recurso importante que facilitó la locomoción de materiales, como vidrieros y reactivos, a las aulas, además de movilizar la participación del grupo en la discusión de los experimentos. Los universitarios en cuestión tuvieron la oportunidad de crear un método de clases experimentales, desarrollar un plan y poner en práctica las propuestas, interactuando con una diversidad cultural local, fortaleciendo la inseparabilidad entre docencia, investigación y extension.Este trabalho refere-se aos estudos realizados por um grupo de estudantes de licenciatura em química ao implementar aulas práticas por meio de um laboratório itinerante, montado em um carrinho de supermercado. A experiência foi desenvolvida no Colégio Estadual Aurelino Leal (CEAL) em Itacaré-BA, por meio de atividade de extensão do Programa de Educação Tutorial (PET) – Licenciatura em Química da Universidade Federal de São Carlos (UFSCar), campus Araras-SP. Realizaram-se atividades práticas dentro de salas de aula, empregando metodologia baseada em questões científicas interativas, em que os estudantes alcançavam aos resultados a partir de reflexões e debates propostos. Os licenciandos, na condição de professores, foram mediadores no processo de ensino-aprendizagem, obtendo resultados significativos, haja visto o envolvimento dos discentes do colégio no processo. A experiência demonstrou que o laboratório móvel foi um importante recurso que facilitou a locomoção dos materiais, como vidrarias e reagentes, às salas de aula, além de mobilizar a participação da turma na discussão dos experimentos. Os universitários em questão tiveram a oportunidade de criar um método de aulas experimentais, desenvolver um planejamento e colocar em prática as propostas, ao passo que interagiram com uma diversidade cultural local, fortalecendo a indissociabilidade entre ensino, pesquisa e extensão.

The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents

On March 11, 2020, the World Health Organization (WHO) officially declared the outbreak caused by the new coronavirus (SARS-CoV-2) a pandemic. The rapid spread of the disease surprised the scientific and medical community. Based on the latest reports, news, and scientific articles published, there is no doubt that the coronavirus has overloaded health systems globally. Practical actions against the recent emergence and rapid expansion of the SARS-CoV-2 require the development and use of tools for discovering new molecular anti-SARS-CoV-2 targets. Thus, this review presents bioinformatics and molecular modeling strategies that aim to assist in the discovery of potential anti-SARS-CoV-2 agents. Besides, we reviewed the relationship between SARS-CoV-2 and innate immunity, since understanding the structures involved in this infection can contribute to the development of new therapeutic targets. Bioinformatics is a technology that assists researchers in coping with diseases by investigating genetic sequencing and seeking structural models of potential molecular targets present in SARS-CoV2. The details provided in this review provide future points of consideration in the field of virology and medical sciences that will contribute to clarifying potential therapeutic targets for anti-SARS-CoV-2 and for understanding the molecular mechanisms responsible for the pathogenesis and virulence of SARS-CoV-2

Neotropical freshwater fisheries : A dataset of occurrence and abundance of freshwater fishes in the Neotropics

The Neotropical region hosts 4225 freshwater fish species, ranking first among the world's most diverse regions for freshwater fishes. Our NEOTROPICAL FRESHWATER FISHES data set is the first to produce a large-scale Neotropical freshwater fish inventory, covering the entire Neotropical region from Mexico and the Caribbean in the north to the southern limits in Argentina, Paraguay, Chile, and Uruguay. We compiled 185,787 distribution records, with unique georeferenced coordinates, for the 4225 species, represented by occurrence and abundance data. The number of species for the most numerous orders are as follows: Characiformes (1289), Siluriformes (1384), Cichliformes (354), Cyprinodontiformes (245), and Gymnotiformes (135). The most recorded species was the characid Astyanax fasciatus (4696 records). We registered 116,802 distribution records for native species, compared to 1802 distribution records for nonnative species. The main aim of the NEOTROPICAL FRESHWATER FISHES data set was to make these occurrence and abundance data accessible for international researchers to develop ecological and macroecological studies, from local to regional scales, with focal fish species, families, or orders. We anticipate that the NEOTROPICAL FRESHWATER FISHES data set will be valuable for studies on a wide range of ecological processes, such as trophic cascades, fishery pressure, the effects of habitat loss and fragmentation, and the impacts of species invasion and climate change. There are no copyright restrictions on the data, and please cite this data paper when using the data in publications