2 research outputs found
Allelic variants of DYX1C1 are not associated with dyslexia in India
Dyslexia is a hereditary neurological disorder that manifests as an
unexpected difficulty in learning to read despite adequate
intelligence, education, and normal senses. The prevalence of dyslexia
ranges from 3 to 15% of the school aged children. Many genetic studies
indicated that loci on 6p21.3, 15q15-21, and 18p11.2 have been
identified as promising candidate gene regions for dyslexia. Recently,
it has been suggested that allelic variants of gene, DYX1C1 influence
dyslexia. In the present study, exon 2 and 10 of DYX1C1 has been
analyzed to verify whether these single nucleotide polymorphisms (SNPs)
influence dyslexia, in our population. Our study identified 4 SNPs
however, none of these SNPS were found to be significantly associated
with dyslexia suggesting DYX1C1 allelic variants are not associated
with dyslexia
Allelic variants of DYX1C1 are not associated with dyslexia in India
Dyslexia is a hereditary neurological disorder that manifests as an unexpected difficulty in learning to read despite adequate intelligence, education, and normal senses. The prevalence of dyslexia ranges from 3 to 15% of the school aged children. Many genetic studies indicated that loci on 6p21.3, 15q15-21, and 18p11.2 have been identified as promising candidate gene regions for dyslexia. Recently, it has been suggested that allelic variants of gene, DYX1C1 influence dyslexia. In the present study, exon 2 and 10 of DYX1C1 has been analyzed to verify whether these single nucleotide polymorphisms (SNPs) influence dyslexia, in our population. Our study identified 4 SNPs however, none of these SNPS were found to be significantly associated with dyslexia suggesting DYX1C1 allelic variants are not associated with dyslexia