Hardware-software co-design of AES on FPGA

This paper presents a compact hardware-software co-design of Advanced Encryption Standard (AES) on the field programmable gate arrays (FPGA) designed for low-cost embedded systems. The design uses MicroBlaze, a soft-core processor from Xilinx. The computationally intensive operations of the AES are implemented in hardware for better speed. The sub-byte calculation is designed with the help of the processor carrying out the calculations using hardware blocks implemented using FPGA. By incorporating the processor in the AES design, the total number of slices required to implement the AES algorithm on FPGA is proved to be reduced. The entire AES system design is validated using 460 slices in Spartan-3E XC3S500E, which is one of the low-cost FPGA

E-connectivity Infrastructure and Usage of Software Applications by Gram Panchayats

The study was conducted to assess the e-connectivity infrastructure available in the Gram Panchayat (Village council) and analyze the software applications adopted by the Gram Panchayats. The study area was three blocks of Coimbatore district, Tamil Nadu viz., Karamadai, Periyanaickenpalayam and Thondamuthur. A total of 36 Gram Panchayat presidents formed the sample. The study revealed that all the Gram Panchayats from three blocks were well equipped with e-connectivity, Because of this the respondents were able to adopt the software applications for reducing paper work in the Gram Panchayat

A Study on the Gorgonid bed off Chennai and its qualitative appraisal

Gorgonian corals or horny corals are corrunon tropical and subtropical octocorallian cnidarians having biomedical importance. This group includes the sea fans, sea feathers and sea whips. The discovery of prostaglandins and other natural products from gorgonids triggered off a worldwide hunt for this chemically rich animals. The present paper describes the status of taxonomy of seven species collected from the Kovalam shore, Chennai. They are referable to three families and five genera. Species such as Echinomuricea indica Thomson and Simpson, Gorgonella umbraculum (Ellis and Solander) and Pseudothesea pallida (Nutting) forms the mainstay of Kovalam waters, off Chennai

Hybrid Time-Series Forecasting Models for Traffic Flow Prediction

Traffic flow forecast is critical in today’s transportation system since it is necessary to construct a traffic plan in order to determine a travel route. The goal of this research is to use time-series forecasting models to estimate future traffic in order to reduce traffic congestion on roadways. Minimising prediction error is the most difficult task in traffic prediction. In order to anticipate future traffic flow, the system also requires real-time data from vehicles and roadways. A hybrid autoregressive integrated moving av-erage with multilayer perceptron (ARIMA-MLP) model and a hybrid autoregressive integrated moving average with recurrent neural network (ARIMA-RNN) model are proposed in this paper to address these difficulties. The transportation data are used from the UK Highways data-set. The time-series data are preprocessed using a random walk model. The forecasting models autoregressive inte-grated moving average (ARIMA), recurrent neural net-work (RNN), and multilayer perceptron (MLP) are trained and tested. In the proposed hybrid ARIMA-MLP and ARI-MA-RNN models, the residuals from the ARIMA model are used to train the MLP and RNN models. Then the ef-ficacy of the hybrid system is assessed using the metrics MAE, MSE, RMSE and R2 (peak hour forecast-0.936763, non-peak hour forecast-0.87638 on ARIMA-MLP model and peak hour forecast-0.9416466, non-peak hour fore-cast-0.931917 on ARIMA-RNN model)

Genetic Divergence Studies in Bixa Orellana L. Accessions, an Important Natural Food Dye Plant Using Mahalanobis D2 Multivariate Analysis

Twenty accessions of Bixa orellana L.,were assessed for the genetic divergence using Mahalanobis D2 statistics. The clustering pattern indicated that there was no association between geographical distribution of the accessions and genetic divergence. The characters namely capsule length and breadth, number of seeds/ capsule and seed bixin content of the accessions were analyzed. All these characters like capsule length and breadth, number of seeds per capsule and seed bixin content were contributing maximum to the divergence. Therefore, selection of divergent parents based on these characters is recommended for producing good hybrids

FORMULATION DEVELOPMENT, EVALUATION AND OPTIMIZATION OF MEDICATED LIP ROUGE CONTAINING NIOSOMAL ACYCLOVIR FOR THE MANAGEMENT OF RECURRENT HERPES LABIALIS

Objective: Aim of the study was to formulate, evaluate and optimize medicated Lip rouge containing acyclovir encapsulated inside a novel vesicular carrier, niosome so that the formulation can improve its membrane penetration. Formulating as a cosmetic Lip rouge formulation will also improve patient compliance in the treatment of herpes labialis.Methods: Acyclovir niosomes were prepared by thin film hydration method. Niosomes were evaluated and were optimized by considering the entrapment efficiency and in vitro release profile. The optimized niosomes were incorporated into lipstick, lip balm and lip rouge for selecting the best lip formulation. Based on the in vitro release profile, ease of application and properties of prepared formulations lip rouge was selected and further evaluations were carried out.Results: Among the six formulations of niosomes NF2 has showed 88.49 % entrapment efficiency and 86.97% cumulative drug release in 8 h. The formulation was optimized considering both entrapment efficiency and in vitro release. The optimized formulation of niosomes was incorporated into Lipstick, lip balm and lip rouge. The evaluation results of lipstick, lip balm and lip rouge for in vitro release suggested lip rouge as the best formulation. The percentage cumulative release of drug from optimized lip rouge at the end of 8 h was 84.77%. The percentage cumulative drug release in ex vivo studies for 8 h was 60.88 %.Conclusion: The results suggested that prepared lip rouge containing acyclovir niosomes can effectively deliver the drug than the marketed acyclovir cream and successful therapy of Recurrent Herpes labialis can be achieved

EVALUATION OF ANTIPROLIFERATIVE ACTIVITY OF SIDDHA ANTI-PSORIATIC FORMULATION PANCHAMUGA CHENDHURAM USING CULTURED HUMAN KERATINOCYTE CELL LINES

Objectives: This study was aimed at scientifically evaluating the in vitro antipsoriatic activity of Siddha drug Panchamuga Chendhuram (PMC) in human keratinocyte (HacaT) cell lines. Methods: The Siddha drug PMC tested for antipsoriatic activity on HacaT cell lines was morphologically examined by phase contrast microscopy, and the cell viability was determined by 3- (4, 5 dimethyl thiazole-2 yl) -2.5-diphenyl tetrazolium bromide assay. About 100 μl of different concentrations (2, 6, 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100 μg/ml) of the test samples were prepared in the cell culture medium and incubated for 24 h and 48 h to determine the viable cells. Results: The results revealed that Siddha drug PMC showed hopeful antiproliferative activity. In vitro studies showed that after 24 h and 48 h incubation, the inhibitory concentration 50 (IC50) values of PMC (IC50 20 μg/ml) were 72.08±27.56 μg/ml and 43.91±17.71 μg/ml, respectively, as compared with Asiaticoside as a positive control with an IC50 value of 20.13 μg/ml. Conclusion: Thus, this study provides scientific evidence about the efficacy of the Siddha drug PMC against the HacaT cell lines confirming its traditional use in psoriasis treatment and also emphasizes the need for antipsoriatic evaluation in animal models

Evaluation of anti- inflammatory activity of aqueous extract of Mangifera indica leaves in albino rats

Background: Mangifera indica (MI) commonly known as mango belongs to the family anacardiaceae, distributed in rural and semi urban parts of India. According to Ayurveda, various medical properties are attributed to different parts of the mango tree. The purpose of the study was to evaluate anti-inflammatory activity of aqueous extract of Mangifera indica leaves.Methods: Aqueous extract of Mangifera indica leaves was prepared and tested for anti-inflammatory activity in albino rats weighing 200-250 gm. The in vivo anti-inflammatory activity was evaluated by using Acute (carrageenan induced paw edema) and chronic (Formalin induced paw edema) animal models. Rats were divided into 4 groups, 6 rats in each group. Group I (control) received 0.1 ml 4% gum acacia suspension. Group II and Group III received Mangifera indica extract at doses of 200 mg/kg and 400 mg/kg body weight. Group IV (standard) received diclofenac 10 mg/kg body weight. All the drugs were administered orally. Anti-inflammatory activity was expressed as percentage inhibition of paw edema.Results: The percentage inhibition in carrageenan induced paw edema with 200 mg/kg and 400 mg/kg Mangifera indica extract was 44.8% and 53% and in formalin induced paw edema was 47.5% and 64.4% respectively. The two doses of Mangifera indica extract showed significant anti-inflammatory action (p<0.001) in both models.Conclusions: Aqueous extract of Mangifera indica leaves showed significant dose dependent anti-inflammatory activity